Table of Contents

 

 

 

 

Preface

xvi

1

An Introduction to Anatomy and Physiology

2

 

The Sciences of Anatomy and Physiology

4

 

Anatomy

4

 

Physiology

5

 

Levels of Organization

5

 

An Introduction to Organ Systems

7

 

Homeostasis and System Integration

7

 

Homeostatic Regulation

7

 

Homeostasis and Disease

15

 

The Language of Anatomy

16

 

Surface Anatomy

17

 

Clinical Note Surface Anatomy

18

 

Sectional Anatomy

18

 

Clinical Note Sectional Anatomy and Clinical Technology

22

 

Chapter Review

24

2

The Chemical Level of Organization

28

 

Matter: Atoms and Molecules

29

 

The Structure of an Atom

29

 

Chemical Bonds and Chemical Compounds

31

 

Chemical Notation

34

 

Chemical Reactions

34

 

Basic Energy Concepts

34

 

Clinical Note Kinetic Energy and Injury

35

 

Types of Reactions

36

 

Enzymes and Chemical Reactions

36

 

Inorganic Compounds

37

 

Carbon Dioxide and Oxygen

38

 

Water and its Properties

38

 

Inorganic Acids and Bases

38

 

Clinical Note Understanding pH

40

 

Salts

41

 

Organic Compounds

41

 

Carbohydrates

42

 

Lipids

43

 

Proteins

45

 

Nucleic Acids

49

 

High-Energy Compounds

50

 

Clinical Note Physical Properties of Emergency Medications

52

 

Chemicals and Cells

54

 

Chapter Review

54

3

Cell Structure and Function

58

 

Studying Cells

59

 

An Overview of Cell Anatomy

60

 

The Cell Membrane

61

 

Membrane Structure

63

 

Membrane Transport

64

 

Clinical Note Fluid Movement

68

 

Clinical Note IV Fluid Therapy

70

 

The Cytoplasm

76

 

The Cytosol

76

 

Organelles

76

 

The Nucleus

81

 

Chromosome Structure

81

 

The Genetic Code

82

 

Clinical Note DNA Fingerprinting

82

 

Protein Synthesis

83

 

Clinical Note Recombinant DNA Technology

85

 

The Cell Life Cycle

86

 

Interphase

86

 

Mitosis

87

 

Cytokinesis

87

 

Cell Division and Cancer

88

 

Cell Diversity and Differentiation

88

 

Chapter Review

89

4

The Tissue Level of Organization

94

 

Epithelial Tissue

96

 

Functions of Epithelia

96

 

Intercellular Connections

97

 

The Epithelial Surface

98

 

The Basement Membrane

99

 

Epithelial Renewal and Repair

99

 

Classifying Epithelia

99

 

Clinical Note Cellular Adaptation

100

 

Glandular Epithelia

103

 

Clinical Note Exfoliative Cytology

104

 

Connective Tissues

105

 

Classifying Connective Tissues

103

 

Connective Tissue Proper

105

 

Clinical Note Marfan’s Syndrome

107

 

Clinical Note Blunt Chest Trauma

107

 

Clinical Note EMS and Obesity

107

 

Fluid Connective Tissues

109

 

Supporting Connective Tissues

109

 

Clinical Note Meniscal Knee Injuries

109

 

Membranes

112

 

Mucous Membranes

112

 

Serous Membranes

113

 

The Cutaneous Membrane

113

 

Synovial Membranes

113

 

Muscle Tissue

113

 

Skeletal Muscle Tissue

113

 

Cardiac Muscle Tissue

113

 

Smooth Muscle Tissue

115

 

Neural Tissue

115

 

Tissue Injuries and Repair

116

 

Tissues and Aging

116

 

Aging and Cancer Incidence

117

 

Chapter Review

117

5

The Integumentary System

122

 

Integumentary Structure and Function

123

 

The Epidermis

124

 

Clinical Note Dermatology

124

 

Clinical Note Drug Administration through the Skin

126

 

Clinical Note Skin Color

127

 

Clinical Note Skin Lesions

129

 

The Dermis

132

 

The Subcutaneous Layer

133

 

Clinical Note Medical Conditions of the Skin

133

 

Accessory Structures

134

 

Clinical Note The Hair in Disease

136

 

Clinical Note Hair Loss

136

 

Local Control of Homeostasis in the Integumentary System

138

 

Injury and Repair of the Skin

138

 

Clinical Note Chronic Skin Conditions

140

 

Clinical Note Traumatic Conditions of the Skin

141

 

Aging and the Integumentary System

145

 

Integration with Other Systems

145

 

Chapter Review

147

6

The Skeletal System

150

 

The Structure of Bone

152

 

Macroscopic Features of Bone

152

 

Microscopic Features of Bone

153

 

Clinical Note Intraosseous Needle Placement

154

 

Bone Formation and Growth

156

 

Intramembranous Ossification

156

 

Endochondral Ossification

157

 

Bone Growth and Body Proportions

158

 

Requirements for Normal Bone Growth

158

 

Bone Remodeling and Homeostatic Mechanisms

159

 

The Role of Remodeling in Support

159

 

Homeostasis and Mineral Storage

159

 

Injury and Repair

160

 

Clinical Note Skeletal Injuries

161

 

Aging and the Skeletal System

166

 

Clinical Note Osteoporosis

166

 

An Overview of the Skeleton

166

 

Bone Markings (Surface Features)

166

 

Skeletal Divisions

166

 

The Axial Division

166

 

The Skull

166

 

The Vertebral Column and Thoracic Cage

175

 

Clinical Note Compression Fractures

177

 

The Appendicular Division

179

 

The Pectoral Girdle

179

 

The Upper Limb

182

 

The Pelvic Girdle

183

 

The Lower Limb

185

 

Clinical Note Hip Fractures

186

 

Articulations

187

 

The Classification of Joints

187

 

Clinical Note Rheumatism and Arthritis

189

 

Synovial Joints: Movement and Structure

189

 

Representative Articulations

194

 

Clinical Note Dislocations

195

 

Integration with Other Systems

197

 

Chapter Review

199

7

The Muscular System

200

 

Functions of Skeletal Muscle

208

 

The Anatomy of Skeletal Muscles

208

 

Gross Anatomy

208

 

Microanatomy

209

 

Clinical Note Rigor Mortis

211

 

Clinical Note The Muscular Dystrophies

211

 

Clinical Note Rhabdomyolysis

212

 

The Control of Muscle Fiber Contraction

212

 

The Neuromuscular Junction

212

 

Clinical Note Myasthenia Gravis

214

 

The Contraction Cycle

215

 

Clinical Note Neuromuscular Blockade

216

 

Clinical Note Interference with Neural Control Mechanisms

216

 

Muscle Mechanics

218

 

The Frequency of Muscle Fiber Stimulation

218

 

Clinical Note The Disease Called Tetanus

219

 

The Number of Muscle Fibers Involved

219

 

Isotonic and Isometric Contractions

220

 

Muscle Elongation

221

 

The Energetics of Muscular Activity

221

 

ATP and CP Reserves

221

 

ATP Generation

221

 

Muscle Fatigue

223

 

The Recovery Period

223

 

Muscle Performance

224

 

Types of Skeletal Muscle Fibers

224

 

Physical Conditioning

224

 

Cardiac and Smooth Muscle Tissues

225

 

Cardiac Muscle Tissue

225

 

Clinical Note Laboratory Testing in Heart Attack

226

 

Smooth Muscle Tissue

226

 

Anatomy of the Muscular System

227

 

Origins, Insertions, and Actions

230

 

Mimes of Skeletal Muscles

230

 

The Axial Muscles

231

 

Clinical Note Spasmodic Torticollis

234

 

Clinical Note Musculoskeletal Back Disorders

236

 

Clinical Note Hernias

238

 

The Appendicular Muscles

239

 

Clinical Note Intramuscular Drug Injection

243

 

Clinical Note Fibromyalgia

251

 

Aging and the Muscular System

251

 

Integration with Other Systems

253

 

Chapter Review

253

8

The Nervous System

258

 

The Nervous System

260

 

Cellular Organization in Neural Tissue

261

 

Neurons

261

 

Neuroglia

263

 

Clinical Note Demyelination Disorders

265

 

Anatomical Organization of Neurons

265

 

Neuron Function

266

 

The Membrane Potential

266

 

Clinical Note Neurotoxins in Seafood

268

 

Propagation of an Action Potential

268

 

Neural Communication

270

 

Structure of a Synapse

271

 

Synaptic Function and Neurotransmitters

271

 

Clinical Note Organophosphate Poisoning

273

 

Clinical Note Neurotransmitters

273

 

Neuronal Pools

273

 

The Central Nervous System

274

 

The Meninges

274

 

Clinical Note Burr Holes

275

 

Clinical Note Epidural and Subdural Damage

276

 

Clinical Note Nervous System Infections

276

 

The Spinal Cord

278

 

Clinical Note Spinal-Cord Injuries

280

 

The Brain

282

 

The Ventricles of the Brain

284

 

Clinical Note Hydrocephalus

286

 

Clinical Note Aphasia and Dyslexia

289

 

Clinical Note Seizures

291

 

The Peripheral Nervous System

294

 

The Cranial Nerves

294

 

The Spinal Nerves

297

 

Nerve Plexuses

298

 

Reflexes

298

 

Clinical Note Reflexes

302

 

Sensory and Motor Pathways

303

 

Clinical Note Extrapyramidal Motor Syndromes

305

 

Clinical Note Cerebral Palsy

305

 

Clinical Note Headache

306

 

The Autonomic Nervous System

306

 

The Sympathetic Division

308

 

Clinical Note Sympathetic Nervous System

309

 

The Parasympathetic Division

310

 

Clinical Note Parasympathetic Nervous System

312

 

Relationships Between the Sympathetic and Parasympathetic Divisions

313

 

Aging and the Nervous System

314

 

Clinical Note Alzheimer’s Disease

314

 

Clinical Note Cerebrovascular Accident (Stroke)

314

 

Clinical Note Neurologic Trauma

316

 

Integration with Other Systems

319

 

Chapter Review

319

9

The General and Special Senses

326

 

The General Senses

328

 

Pain

328

 

Temperature

329

 

Touch, Pressure, and Position

329

 

Clinical Note Pain

330

 

Chemical Detection

332

 

The Special Senses

333

 

Smell

333

 

The Olfactory Pathways

334

 

Taste

334

 

The Taste Pathways

335

 

Vision

336

 

The Accessory Structures of the Eye

336

 

The Eye

337

 

Clinical Note Anisocoria

340

 

Clinical Note Hyphema

343

 

Clinical Note Cataracts

344

 

Visual Physiology

345

 

Clinical Note Visual Acuity

345

 

Clinical Note Accommodation Problems

346

 

The Visual Pathway

347

 

Clinical Note Night Blindness

348

 

Clinical Note Eye Emergencies

350

 

Equilibrium and Hearing

351

 

The Anatomy of the Ear

351

 

Equilibrium

353

 

Hearing

356

 

Clinical Note Hearing Loss

359

 

Aging and the Senses

360

 

Smell

360

 

Taste

361

 

Vision

361

 

Hearing

361

 

Chapter Review

361

10

The Endocrine System

366

 

An Overview of the Endocrine System

368

 

The Structure of Hormones

368

 

The Mechanisms of Hormonal Action

369

 

The Secretion and Distribution of Hormones

371

 

Clinical Note Endocrine Emergencies

372

 

The Control of Endocrine Activity

372

 

The Pituitary Gland

373

 

The Anterior Pituitary Gland

374

 

The Posterior Pituitary Gland

377

 

Clinical Note Vasopressin

378

 

Clinical Note Diabetes Insipidus

379

 

The Thyroid Gland

379

 

Thyroid Follicles and Thyroid Hormones

379

 

The C Cells of the Thyroid Gland: Calcitonin

380

 

Clinical Note Disorders of the Thyroid Gland

381

 

The Parathyroid Glands

384

 

The Adrenal Glands

385

 

The Adrenal Cortex

385

 

The Adrenal Medulla

386

 

Clinical Note Disorders of the Adrenal Glands

387

 

The Pineal Gland

388

 

The Pancreas

389

 

Regulation of Blood Glucose Concentrations

389

 

Clinical Note Diabetes Mellitus

391

 

The Endocrine Tissues of Other Organ Systems

393

 

The Intestines

393

 

The Kidneys

394

 

The Heart

394

 

Clinical Note Natriuretic Peptides

394

 

The Thymus

394

 

The Gonads

395

 

Clinical Note Estrogen Replacement Therapy

395

 

Adipose Tissue

395

 

Patterns of Hormonal Interaction

396

 

Hormones and Growth

396

 

Hormones and Stress

397

 

Clinical Note The Physiologic Response to Stress

398

 

Hormones and Behavior

398

 

Hormones and Aging

398

 

Clinical Note Endocrine Disorders

399

 

Integration with Other Systems

401

 

Chapter Review

401

11

The Cardiovascular System: Blood

406

 

The Functions of Blood

407

 

The Composition of Blood

408

 

Blood Collection and Analysis

408

 

Plasma

408

 

Plasma Proteins

410

 

Formed Elements

410

 

The Production of Formed Elements

410

 

Red Blood Cells

411

 

Clinical Note Sickle Cell Disease

412

 

Clinical Note Rapid Blood Tests

416

 

Clinical Note Emergency Transfusions

419

 

White Blood Cells

419

 

Clinical Note Hemolytic Disease of the Newborn

419

 

Clinical Note Testing for Blood Compatibility

420

 

Clinical Note Blood Transfusion Reactions

420

 

Platelets

424

 

Clinical Note Blood Banking and Transfusion

424

 

Homostasis

425

 

The Clotting Process

426

 

Clinical Note Aspirin

426

 

Clot Retraction and Removal

427

 

Clinical Note Heparin and Fibrinolytic Therapy

428

 

Clinical Note Abnormal Hemostasis

429

 

Clinical Note Fibrinolytic Therapy: The Era of Reperfusion

429

 

Chapter Review

431

12

The Cardiovascular System: The Heart

436

 

The Heart’s Place in the Circulatory System

437

 

The Anatomy and Organization of the Heart

438

 

The Surface Anatomy of the Heart

438

 

The Heart Wall

439

 

Clinical Note Chagas’ Disease

442

 

Internal Anatomy and Organization

442

 

Clinical Note Mitral Valve Prolapse

445

 

Clinical Note Valvular Heart Disease

445

 

The Blood Supply to the Heart

445

 

Clinical Note Coronary Artery Disease

447

 

The Heartbeat

450

 

Contractile Cells

450

 

The Conducting System

452

 

Clinical Note Defibrillation

453

 

The Electrocardiogram

455

 

Clinical Note Emergency Cardiac Care

457

 

The Cardiac Cycle

457

 

Heart Dynamics

458

 

Factors that Control Cardiac Output

459

 

Clinical Note Blunt Myocardial Injury

459

 

Clinical Note the Denervated Heart

461

 

Clinical Note Extracellular Ions, Temperature, and Cardiac Output

461

 

Chapter Review

462

13

The Cardiovascular System: Blood Vessels and Circulation

466

 

The Structure of Blood Vessels

468

 

Arteries

468

 

Capillaries

470

 

Clinical Note Arteriosclerosis

470

 

Veins

472

 

Circulatory Physiology

472

 

Factors that Affect Blood Flow

472

 

Cardiovascular Pressures within the Systemic Circuit

473

 

Clinical Note Hypertension

474

 

Clinical Note Capillary Physiology

476

 

Cardiovascular Regulation

476

 

Clinical Note Vital Signs

477

 

Autoregulation of Blood Flow

478

 

Neural Control of Blood Pressure and Blood Flow

479

 

Hormones and Cardiovascular Regulation

481

 

Patterns of Cardiovascular Response

482

 

Exercise and the Cardiovascular System

482

 

The Cardiovascular Response to Hemorrhage

483

 

Clinical Note Shock

483

 

The Blood Vessels

484

 

The Pulmonary Circulation

484

 

Clinical Note Acute Pulmonary Embolism

484

 

The Systemic Circulation

487

 

Clinical Note Aneurysm

488

 

Clinical Note Vasculitis

493

 

Clinical Note Acute Arterial Occlusion

495

 

Clinical Note Peripheral Vascular Conditions

498

 

Fetal Circulation

500

 

Aging and the Cardiovascular System

501

 

Clinical Note Vascular Trauma

502

 

Integration with Other Systems

503

 

Chapter Review

505

14

The Lymphatic System and Immunity

510

 

Organization of the Lymphatic System

512

 

Functions of the Lymphatic System

512

 

Lymphatic Vessels

513

 

Lymphocytes

513

 

Lymphoid Nodules

515

 

Lymphoid Organs

515

 

Clinical Note “Swollen Glands”

516

 

Clinical Note Injury to the Spleen

517

 

The Roles of the Lymphatic System in Body Defense

518

 

Nonspecific Defenses

519

 

Physical Barriers

519

 

Phagocytes

519

 

Immunological Surveillance

520

 

Interferons

520

 

Complement

521

 

Inflammation

521

 

Fever

522

 

Clinical Note Fever

522

 

Specific Defenses: The Immune Response

522

 

Types of Immunity

522

 

Properties of Immunity

523

 

Clinical Note Immunology

524

 

An Overview of the Immune Response

527

 

T Cells and Cell-Mediated Immunity

527

 

B Cells and Antibody-Mediated Immunity

529

 

Clinical Note AIDS

531

 

Hormones of the Immune System

532

 

Patterns of Immune Response

534

 

Immune Disorders

534

 

Clinical Note Allergies

536

 

Aging and the Immune Response

537

 

Integration with Other Systems

537

 

Clinical Note Anaphylaxis

539

 

Chapter Review

540

15

The Respiratory System

546

 

The Functions of the Respiratory System

547

 

The Organization of the Respiratory System

548

 

The Respiratory Tract

548

 

The Nose

548

 

The Pharynx

549

 

The Larynx

550

 

Clinical Note Cystic Fibrosis

550

 

The Trachea

552

 

The Bronchi

553

 

Clinical Note Bronchial Angles

553

 

The Bronchioles

553

 

The Alveolar Ducts and Alveoli

553

 

Clinical Note Bronchiolitis and Respiratory Synctial Vir Infections

556

 

The Respiratory Membrane

556

 

Clinical Note Pulmonary Embolism

556

 

The Lungs

556

 

Clinical Note Pneumonia

557

 

The Pleural Cavities

558

 

Clinical Note Tension Pneumothorax and Chest Decompression

559

 

Clinical Note Tuberculosis

560

 

Clinical Note Tobacco Abuse

560

 

Respiratory Physiology

560

 

Pulmonary Ventilation

560

 

Clinical Note Respiratory System Interventions

562

 

Clinical Note Pulmonary Function Tests

565

 

Gas Exchange

565

 

Clinical Note Chronic Respiratory System Diseases

566

 

Gas Transport

568

 

Clinical Note Upper Respiratory Infection

569

 

Clinical Note Pulse Oximetry

570

 

Clinical Note Carbon Monoxide Poisoning

571

 

Clinical Note Arterial Blood Gas Measurements

572

 

The Control of Respiration

573

 

The Local Control of Respiration

573

 

Control by the Respiratory Centers of the Brain

573

 

The Reflex Control of Respiration

574

 

Clinical Note Hypoxic Drive

575

 

Clinical Note Lung Cancer

575

 

Clinical Note Capnography

576

 

Clinical Note SIDS

577

 

Control by Higher Centers

577

 

Respiratory Changes at Birth

578

 

Aging and the Respiratory System

578

 

Integration with Other Systems

578

 

Chapter Review

580

16

The Digestive System

584

 

An Overview of the Digestive Tract

586

 

Histological Organization

587

 

Clinical Note Ascites

588

 

The Movement of Digestive Materials

588

 

The Oral Cavity

589

 

The Tongue

589

 

Salivary Glands

590

 

Clinical Note Salivary Gland Disorders

590

 

Teeth

590

 

The Pharynx

592

 

The Esophagus

592

 

Swallowing

592

 

Clinical Note Swallowed Foreign Bodies

593

 

Clinical Note Esophagitis and Diaphragmatic (Hiatal) Hernias

593

 

The Stomach

593

 

The Gastric Wall

595

 

Clinical Note Peptic Ulcers

595

 

The Regulation of Gastric Activity

596

 

Clinical Note Stomach Cancer

598

 

The Small Intestine

598

 

Clinical Note Upper GI Bleeding

599

 

The Intestinal Wall

600

 

Intestinal Secretions

601

 

Clinical Note Vomiting

601

 

Digestion in the Small Intestine

602

 

The Pancreas

603

 

Histological Organization

603

 

The Control of Pancreatic Secretion

603

 

Clinical Note Pancreatitis

604

 

The Liver

605

 

Anatomy of the Liver

605

 

Clinical Note Portal Hypertension

607

 

Clinical Note Hepatic Abscesses

608

 

Liver Functions

609

 

Clinical Note Liver Transplant

609

 

Clinical Note Hepatitis

610

 

The Gallbladder

611

 

Clinical Note Biliary Colic and Cholecystitis

612

 

The Large Intestine

613

 

The Cecum

614

 

Clinical Note Appendicitis

614

 

The Colon

614

 

The Rectum

615

 

Clinical Note Hemorrhoids

615

 

The Functions of the Large Intestine

615

 

Clinical Note Colon and Rectum Cancers

615

 

Clinical Note Diverticulosis

616

 

Clinical Note Diarrhea and Constipation

616

 

Clinical Note Diverticulitis

617

 

Negation and Absorption

617

 

The Processing and Absorption of Nutrients

618

 

Clinical Note Lactose Intolerance

620

 

Liver and Electrolyte Absorption

620

 

The Absorption of Vitamins

620

 

Clinical Note Emergency Vitamins?

620

 

Clinical Note Malabsorption Syndromes

621

 

Aging and the Digestive System

621

 

Integration with Other Systems

621

 

Clinical Note Abdominal Pain

623

 

Chapter Review

623

17

Nutrition and Metabolism

628

 

Cellular Metabolism

630

 

Carbohydrate Metabolism

631

 

Clinical Note Cellular Hypoxia

635

 

Alternate Catabolic Pathways

635

 

Lipid Metabolism

636

 

Protein Metabolism

638

 

Clinical Note Complications of Diabetes Mellitus

639

 

Clinical Note Dietary Fats and Cholesterol

639

 

Nucleic Acid Metabolism

640

 

A Summary of Cellular Metabolism

641

 

Diet and Nutrition

642

 

Food Groups and the Food Pyramid

642

 

Minerals, Vitamins, and Water

644

 

Clinical Note Vitamins

645

 

Clinical Note Beriberi

647

 

Diet and Disease

648

 

Bioenergetics

648

 

The Energy Content of Food

648

 

Metabolic Rate

648

 

Thermoregulation

649

 

Clinical Note Fire-Ground Rehabilitation

650

 

Aging and Nutritional Requirements

651

 

Clinical Note Nutrition and Emergency Medical Services

651

 

Clinical Note Nutrition

652

 

Chapter Review

653

18

The Urinary System

658

 

The Organization of the Urinary System

660

 

The Kidneys

660

 

Superficial and Sectional Anatomy

661

 

The Blood Supply to the Kidneys

662

 

The Nephron

663

 

Basic Principles of Urine Production

666

 

Filtration at the Glomerulus

667

 

Reabsorption and Secretion Along the Renal Tubule

668

 

Clinical Note Acute Renal Failure

672

 

The Control of Kidney Function

672

 

Clinical Note Hemodialysis

672

 

Clinical Note The Treatment of Kidney Failure

673

 

Urine Transport, Storage, and Elimination

675

 

The Ureters and Urinary Bladder

675

 

Clinical Note Kidney Stones

675

 

The Urethra

677

 

Clinical Note Urinary Tract Infections

678

 

The Micturition Reflex and Urination

679

 

Clinical Note Incontinence

680

 

Fluid, Electrolyte, and Acid-Base Balance

680

 

Fluid and Electrolyte Balance

681

 

Acid-Base Balance

684

 

Clinical Note Disturbances of Acid-Base Balance

687

 

Aging and the Urinary System

688

 

Clinical Note Renal Trauma

688

 

Integration with Other Systems

690

 

Chapter Review

690

19

The Reproductive System

696

 

The Reproductive System of the Male

697

 

The Testes

698

 

Clinical Note Cryptorchidism

698

 

Clinical Note Testicular Cancer

700

 

Clinical Note Testicular Torsion

700

 

The Male Reproductive Tract

702

 

The Accessory Glands

704

 

Clinical Note Prostatitis

704

 

Semen

704

 

The Penis

704

 

Clinical Note Priapism

706

 

Hormones and Male Reproductive Function

706

 

Clinical Note Male Genital Trauma

707

 

The Reproductive System of the Female

707

 

The Ovaries

709

 

Clinical Note Mittelschmerz

711

 

Clinical Note Ruptured Ovarian Cysts

711

 

The Uterine Tubes

712

 

The Uterus

712

 

Clinical Note Endometritis

713

 

Clinical Note Endometriosis

713

 

Clinical Note Pelvic Inflammatory Disease (PID)

714

 

The Vagina

714

 

Clinical Note Menstrual Irregularities

715

 

Clinical Note Amenorrhea

715

 

The External Genitalia

715

 

The Mammary Glands

716

 

Clinical Note Endocrine Effects on the Breast

716

 

Clinical Note Breast Cancer

717

 

Hormones and the Female Reproductive Cycle

717

 

Clinical Note Dermoid Cysts

717

 

Clinical Note Infertility

720

 

The Physiology of Sexual Intercourse

720

 

Male Sexual Function

720

 

Clinical Note Date Rape

721

 

Female Sexual Function

721

 

Clinical Note Sexually Transmitted Diseases

721

 

Aging and the Reproductive System

721

 

Menopause

722

 

The Male Climacteric

722

 

Integration with Other Systems

722

 

Clinical Note Birth Control Strategies

724

 

Chapter Review

726

20

Development and Inheritance

732

 

An Overview of Topics in Development

733

 

Fertilization

734

 

Activation of the Oocyte

734

 

An Overview of Prenatal Development

735

 

The First Trimester

736

 

Cleavage and Blastocyst Formation

736

 

Clinical Note Ectopic Pregnancy

737

 

Implantation

737

 

Placentation

741

 

Embryogenesis

742

 

Clinical Note Teratogenicity

743

 

The Second and Third Trimesters

746

 

The Effects of Pregnancy on Maternal Systems

746

 

Clinical Note Physiologic Changes of Pregnancy

744

 

Structural and Functional Changes in the Uterus

751

 

Clinical Note Fetal Development

750

 

Labor and Delivery

751

 

The Stages of Labor

751

 

Premature Labor

752

 

Multiple Births

752

 

Clinical Note Obstetrical Terminology

753

 

Postnatal Development

753

 

The Neonatal Period, Infancy, and Childhood

754

 

Clinical Note Postnatal Development

754

 

Adolescence and Maturity

756

 

Clinical Note Abortion

756

 

Genetics, Development, and Inheritance

757

 

Genes and Chromosomes

757

 

Clinical Note Inherited Disorders: Emergency Implications

760

 

The Human Genome Project

761

 

Clinical Note Chromosomal Abnormalities and Genetic Analysis

763

 

Clinical Note Trauma During Pregnancy

764

 

Chapter Review

765

Appendix I

Roles and Responsibilities of Emergency Medical Personnel

771

Appendix II

A Periodic Chart of the Elements

780

Appendix III

Weights and Measures

781

Appendix IV

Normal Physiological Values

784

Appendix V

Key Notes

786

Appendix VI

Answers to Concept Check and Chapter Review Questions

792

 

Glossary/Index

827