Table of Contents

 

 

 

PART I

BASIC SCIENCE

 

1

Fertilization and Embryogenesis

1

 

Meiosis, Fertilization, Implantation, Embryonic Development, Sexual Differentiation   Edith Cheng and Vern L. Katz

 

2

Reproductive Genetics

21

 

Gene Structure, Mutation, Molecular Tools, Types of Inheritance, Counseling Issues, Oncogenes   Edith Cheng and Vern L. Katz

 

3

Reproductive Anatomy

43

 

Gross and Microscopic, Clinical Correlations   Vern L. Katz

 

4

Reproductive Endocrinology

73

 

Neuroendocrinology, Gonadotropins, Sex Steroids, Prostaglandins, Ovulation, Menstruation, Hormone Assay   Rogerio A. Lobo

 

5

Evidence-Based Medicine and Clinical Epidemiology   Vern L. Katz

121

6

Medical, Legal, and Ethical Issues   Fillmore Buckner and Gretchen M. Lentz

129

PART II

COMPREHENSIVE EVALUATION OF THE FEMALE

 

7

History, Physical Examination, and Preventive Health Care

137

 

General, Gynecologic, and Psychosocial History and Examination, Health Care Maintenance, Disease Prevention   Gretchen M. Lentz

 

8

Differential Diagnosis of Major Gynecologic Problems by Age Group

153

 

Vaginal Bleeding, Pelvic Pain, Pelvic Mass   Gretchen M. Lentz

 

9

Emotional Aspects of Gynecology

177

 

Sexual Dysfunction, Eating Disorders, Substance Abuse, Depression, Grief, Loss   Gretchen M. Lentz

 

10

Rape, Incest, and Domestic Violence

203

 

Discovery, Management, Counseling   Gretchen M. Lentz

 

11

Diagnostic Procedures

215

 

Imaging, Endometrial Sampling, Endoscopy: Indications and Contraindications, Complications   Vern L. Katz

 

PART III

GENERAL GYNECOLOGY

 

12

Congenital Abnormalities of the Female Reproductive Tract

241

 

Anomalies of the Vagina, Cervix, Uterus, and Adnexa   Vern L. Katz and Gretchen M. Lentz

 

13

Pediatric and Adolescent Gynecology

257

 

Gynecologic Examination, Infections, Trauma, Pelvic Mass, Precocious Puberty   Ann Jeannette Davis and Vern L. Katz

 

14

Family Planning

275

 

Contraception, Sterilization, and Pregnancy Termination   Daniel R. Mishell, Jr.

 

15

Breast Diseases

327

 

Diagnosis and Treatment of Benign and Malignant Disease   Fidel A. Valea and Vern L. Katz

 

16

Spontaneous and Recurrent Abortion

359

 

Etiology, Diagnosis, Treatment   Vern L. Katz

 

17

Ectopic Pregnancy

389

 

Etiology, Pathology, Diagnosis, Management, Fertility Prognosis   Rogerio A. Lobo

 

18

Benign Gynecologic Lesions

419

 

Vulva, Vagina, Cervix, Uterus, Oviduct, Ovary   Vern L. Katz

 

19

Endometriosis

473

 

Etiology, Pathology, Diagnosis, Management   Rogerio A. Lobo

 

20

Anatomic Defects of the Abdominal Wall and Pelvic Floor

501

 

Abdominal and Inguinal Hernias, Cystocele, Urethrocele, Enterocele, Rectocele, Uterine and Vaginal Prolapse, and Rectal Incontinence: Diagnosis and Management   Gretchen M. Lentz

 

21

Urogynecology

537

 

Physiology of Micturition, Diagnosis of Voiding Dysfunction and Incontinence: Surgical and Nonsurgical Treatment   Gretchen M. Lentz

 

22

Infections of the Lower Genital Tract

569

 

Vulva, Vagina, Cervix, Toxic Shock Syndrome, HIV Infections   Linda O. Eckert and Gretchen M. Lentz

 

23

Infections of the Upper Genital Tract

607

 

Endometritis, Acute and Chronic Salpingitis   Linda O. Eckert and Gretchen M. Lentz

 

24

Preoperative Counseling and Management

633

 

Patient Evaluation, Informed Consent, Infection Prophylaxis, Avoidance of Complications   Vern L. Katz

 

25

Postoperative Counseling and Management

661

 

Fever, Respiratory, Cardiovascular, Thromboembolic, Urinary Tract, Gastrointestinal, Wound, Operative Site, Neurologic Injury, Psychological Sequelae   Vern L. Katz

 

PART IV

GYNECOLOGIC ONCOLOGY

 

26

Principles of Radiation Therapy and Chemotherapy in Gynecologic Cancer

711

 

Basic Principles, Uses, and Complications   Charles Kunos and Steven E. Waggoner

 

27

Immunology and Molecular Oncology in Gynecologic Cancer

731

 

Immunologic Response, Cytokines, Tumor Cell Killing, and Immunotherapy   S. Diane Yamada and Steven E. Waggoner

 

28

Intraepithelial Neoplasia of the Lower Genital Tract (Cervix, Vulva)

743

 

Etiology, Screening, Diagnostic Techniques, Management   Kenneth L. Noller

 

29

Malignant Diseases of the Cervix

759

 

Microinvasive and Invasive Carcinoma: Diagnosis and Management   Anuja Jhingran and Charles Levenback

 

30

Neoplastic Diseases of the Vulva

781

 

Lichen Sclerosus, Intraepithelial Neoplasia, Pagets Disease, Carcinoma   Michael Frumovitz and Diane C. Bodurka

 

31

Malignant Diseases of the Vagina

801

 

Intraepithelial Neoplasia, Carcinoma, Sarcoma   Deborah Jean Dotters and Vern L. Katz

 

32

Neoplastic Diseases of the Uterus

813

 

Endometrial Hyperplasia, Endometrial Carcinoma, Sarcoma: Diagnosis and Management   Karen Lu and Brian M. Slomovitz

 

33

Neoplastic Diseases of the Ovary

839

 

Screening, Benign and Malignant Epithelial and Germ Cell Neoplasms, Sex-Cord Stromal Tumors   Robert L. Coleman and David M. Gershenson

 

34

Neoplastic Diseases of the Fallopian Tubes

883

 

Screening, Benign and Malignant Epithelial and Germ Cell Neoplasms, Sex-Cord Stromal Tumors   Deborah Jean Dotters and Vern L. Katz

 

35

Gestational Trophoblastic Disease

889

 

Hydatidiform Mole, Nonmetastatic and Metastatic Gestational Trophoblastic Tumor: Diagnosis and Management   John J. Kavanagh and David M. Gershenson

 

PART V

REPRODUCTIVE ENDOCRINOLOGY AND INFERTILITY

 

36

Primary and Secondary Dysmenorrhea, Premenstrual Syndrome, and Premenstrual Dysphoric Disorder

901

 

Etiology, Diagnosis, Management   Gretchen M. Lentz

 

37

Abnormal Uterine Bleeding

915

 

Ovulatory and Anovulatory Dysfunctional Uterine Bleeding, Management of Acute and Chronic Excessive Bleeding   Rogerio A. Lobo

 

38

Primary and Secondary Amenorrhea and Precocious Puberty

933

 

Etiology, Diagnostic Evaluation, Management   Rogerio A. Lobo

 

39

Hyperprolactinemia, Galactorrhea, and Pituitary Adenomas

963

 

Etiology, Differential Diagnosis, Natural History, Management   Rogerio A. Lobo

 

40

Hyperandrogenism

979

 

Physiology, Etiology, Differential Diagnosis, Management   Rogerio A. Lobo

 

41

Infertility

1001

 

Etiology, Diagnostic Evaluation, Management, Prognosis   Rogerio A. Lobo

 

42

Menopause

1039

 

Endocrinology, Consequences of Estrogen Deficiency, Effects of Hormone Replacement Therapy, Treatment Regimens   Rogerio A. Lobo

 

 

Index

1073