Table of Contents
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Contributing Authors |
xi |
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Preface to the Third Edition |
xv |
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Preface to the First Edition |
xvii |
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SECTION I |
PATHOPHYSIOLOGY OF PEDIATRIC LIVER DISEASE |
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1 |
Liver Development: From Endoderm to Hepatocytc Torsten
Wuestefeld
and Kenneth S. Zaret |
3 |
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2 |
Functional Development of the
Liver Frederick J. Suchy |
14 |
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3 |
Mechanisms of Bile Formation and Cholestasis Saul
J. Karpen |
28 |
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4 |
The Cholangiopathies Valeer
J. Desmet
and Tania A.D. Roskams |
35 |
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5 |
Acute Liver Failure in Children Estella
M. Alonso, Robert H. Squires, and Peter F. Whitington |
71 |
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6 |
Cirrhosis and Chronic Liver
Failure Stephen Hardy and Ronald E. Kleinman |
97 |
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7 |
Portal Hypertension Benjamin
L. Shneider |
138 |
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8 |
Laboratory Assessment of Liver Function and
Injury in Children Vicky Lee Ng |
163 |
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SECTION II |
CHOLESTATIC LIVER DISEASES |
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9 |
Approach to the Infant with Cholestasis Frederick
J. Suchy |
179 |
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10 |
Medical and Nutritional Management of Cholestasis
in Infants and Children Andrew P. Feranchak
and Ronald J. Sokol |
190 |
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11 |
Neonatal Hepatitis and Congenital
Infections Philip Rosenthal |
232 |
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12 |
Biliary Atresia
and Other Disorders of the Extrahepatic Bile
Ducts William F. Balistreri, Jorge A. Bezerra,
and Frederick C. Ryckman |
247 |
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13 |
Neonatal Jaundice and Disorders of Bilirubin
Metabolism Glenn R. Gourley |
270 |
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14 |
Familial Hepatocellular Cholestasis Frederick
J. Suchy
and Benjamin L. Shneider |
310 |
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15 |
Alagille Syndrome Binita
M. Kamath,
Nancy B. Spinner, and David A. Piccoli |
326 |
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16 |
Diseases of the Gallbladder in Infancy,
Childhood, and Adolescence James E. Heubi |
346 |
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SECTION III |
HEPATITIS AND IMMUNE DISORDERS |
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17 |
Acute and Chronic Viral
Hepatitis Jay A. Hochman and William F. Balistreri |
369 |
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18 |
Autoimmune Hepatitis Giorgina
Mieli-Vergani
and Diego Vergani |
447 |
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19 |
Sclerosing Cholangitis |
459 |
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20 |
Drug-Induced Liver Disease Eve
A. Roberts |
478 |
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21 |
Liver Disease in Immunodeficiencies Nedim
Hadžić |
513 |
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SECTION IV |
METABOLIC LIVER DISEASE |
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22 |
Laboratory Diagnosis of Inborn Errors of
Metabolism Devin Oglesbee and Piero
Rinaldo |
531 |
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23 |
α1-Antitrypsin
Deficiency David H. Perlmutter |
545 |
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24 |
Cystic Fibrosis Liver Disease Andrew
P. Feranchak |
572 |
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25 |
Inborn Errors of Carbohydrate
Metabolism Fayez K. Ghishan
and Mona Zawaideh |
595 |
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26 |
Copper Metabolism and Copper Storage Disorders Judith
A. O'Connor and Ronald J. Sokol |
626 |
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27 |
Iron Storage Disorders Alex
S. Knisely
and Michael R. Narkewicz |
661 |
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28 |
Heme Biosynthesis and the Porphyrias Robert
J. Desnick,
Kenneth H. Astrin, and Karl E. Anderson |
677 |
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29 |
Tyrosinemia Grant
Mitchell, Pierre A. Russo, Josée Dubois, and Fernando
Alvarez |
694 |
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30 |
The Liver in Lysosomal
Storage Diseases T. Andrew Burrow, Kevin E. Bove,
and Gregory A. Grabowski |
714 |
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31 |
Disorders of Bile Acid Synthesis and Metabolism:
A Metabolic Basis for Liver Disease Kenneth D.R. Setchell
and Nancy C. O'Connell |
736 |
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32 |
Inborn Errors of Mitochondrial Fatty Acid
Oxidation Jerry Angdisen, Majed
Dasouki,
and Jamal A. Ibdah |
767 |
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33 |
Mitochondrial Hepatopathies Ronald
J. Sokol |
803 |
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34 |
Nonalcoholic Fatty Liver
Disease Jeffrey B. Schwimmer |
830 |
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35 |
Peroxisomal Diseases Paul
A. Watkins and Kathleen B. Schwarz |
840 |
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36 |
Urea Cycle Disorders Marshall
L. Summar |
858 |
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SECTION V |
OTHER CONDITIONS AND ISSUES IN PEDIATRIC HEPATOLOGY |
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37 |
Bacterial, Parasitic, and Fungal Infections of
the Liver Donald A. Novak, Gregory Y. Lauwers,
and Richard L. Kradin |
871 |
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38 |
Systemic Disease and the Liver Michael
K. Farrell and John C. Bucuvalas |
897 |
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39 |
Fibrocystic Liver Disease Maureen
M. Jonas and Antonio R. Perez-Atayde |
928 |
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40 |
Tumors of the Liver Dolores López-Terrada
and Milton J. Finegold |
943 |
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41 |
Liver Transplantation in
Children Greg Tiao, Maria H. Alonso, and
Frederick C. Ryckman |
975 |
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Index |
995 |
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Color Plates Appear After page 366 |
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