Table of Contents

 

 

 

 

Preface

ix

 

Acknowledgments

x

 

About the Authors

xi

Chapter 1

General Physiology

1

 

Homeostasis

1

 

Membrane Transport Mechanisms

5

 

Membrane Potentials

11

 

Synaptic Transmission

16

 

Skeletal Muscle

16

 

Smooth Muscle

24

 

Study Questions

26

 

Answers

28

Chapter 2

Neurophysiology

29

 

The Nervous System

29

 

Brain Extracellular Fluids

37

 

Cellular Neuroscience

42

 

Sensory Neurophysiology

49

 

The Visual System

57

 

The Auditory and Vestibular Systems

71

 

Gustation and Olfaction

80

 

Motor Neurophysiology

83

 

The Autonomic Nervous System

92

 

Integrative and Behavioral Functions

97

 

Study Questions

110

 

Answers

112

Chapter 3

Blood

113

 

The Composition of Blood

113

 

Hematopoiesis

114

 

Red Blood Cells

118

 

Blood Clotting

121

 

Study Questions

128

 

Answers

130

Chapter 4

Cardiovascular Physiology

131

 

The Cardiovascular System

131

 

Hemodynamics

132

 

Structure and Function of Cardiac Muscle

134

 

Cardiac Electrophysiology

137

 

The Cardiac Cycle

145

 

Cardiac Output

152

 

Vascular Function

157

 

Neurohumoral Regulation of the Cardiovascular System

162

 

Regional Blood Flow

164

 

The Capillary Microcirculation

168

 

Study Questions

171

 

Answers

173

Chapter 5

Pulmonary Physiology

175

 

The Respiratory System

175

 

Mechanics of Breathing

178

 

Ventilation and Carbon Dioxide Elimination

190

 

Pulmonary Blood Flow

196

 

Oxygenation

199

 

Control of Breathing

207

 

Study Questions

211

 

Answers

213

Chapter 6

Renal Physiology and Acid-Base Balance

215

 

The Renal System

215

 

Glomerular Filtration

220

 

Clearance

224

 

Renal Sodium Handling and Diuretics

228

 

Urine Concentration and Dilution

232

 

Regulation of Extracellular Fluid Volume

236

 

Magnesium Homeostasis

241

 

Renal Urea Handling

241

 

Renal Calcium Handling

242

 

Renal Phosphate Handling

243

 

Potassium Balance

243

 

Acid-Base Physiology

245

 

Study Questions

255

 

Answers

257

Chapter 7

Gastrointestinal Physiology

259

 

The Gastrointestinal System

259

 

Control Mechanisms in Gastrointestinal Physiology

262

 

The Mouth and Esophagus

266

 

The Stomach

270

 

The Pancreas

276

 

The Liver

279

 

The Small Intestine

286

 

The Large Intestine

297

 

Enteric Motility

299

 

Study Questions

304

 

Answers

306

Chapter 8

Endocrine Physiology

307

 

The Endocrine System

307

 

The Hypothalamus and the Pituitary Gland

316

 

The Thyroid Gland

321

 

The Adrenal Glands

325

 

The Endocrine Pancreas

335

 

Parathyroid Hormone, Vitamin D, and Calcitonin

341

 

The Hypothalamic-Pituitary-Gonadal

 

 

Endocrine Axis

347

 

Study Questions

350

 

Answers

352

Chapter 9

Reproductive Physiology

353

 

The Reproductive System

353

 

Sexual Differentiation

354

 

Male Reproductive Physiology

359

 

Female Reproductive Physiology

363

 

Human Sexual Responses

369

 

Fertilization and the Establishment of Pregnancy

370

 

The Endocrinology of Pregnancy

375

 

Maternal Adaptation to Pregnancy

378

 

Parturition

379

 

Lactation

380

 

Contraception

382

 

Study Questions

383

 

Answers

385

Chapter 10

Final Examination

387

 

Study Questions

387

 

Answers

405

 

Index

411