Table of Contents

 

 

 

 

Contributors

xi

 

Preface

xv

PART ONE

NEUROMODULATION: ANALYSIS TECHNIQUES

1

1

Use of Quantitative EEG to Predict Therapeutic Outcome in Neuropsychiatric Disorders   Jack Johnstone and Joy Lunt

3

 

Introduction

3

 

Foundations of Clinical EEG: Reliability

4

 

Quantitative EEG

5

 

Quantitative EEG/Erp and Medication Management

7

 

Prediction of Neurofeedback Protocol Efficacy

12

 

Using EEG to Guide Transcranial Magnetic Stimulation

17

 

Conclusion

19

 

References

20

2

EEG Source Analysis: Methods and Clinical Implications   Marco Congedo and Leslie Sherlin

25

 

Introduction

25

 

Method

27

 

Clinical Examples

39

 

Discussion

43

 

References

44

3

ERP-Based Endophenotypes: Application in Diagnosis and Neurotherapy   Juri D. Kropotov, Andreas Mueller, and Valery A. Ponomarev

47

 

Introduction

47

 

Event-Related Potentials (ERPs)

48

 

Theoretical Considerations

49

 

New Methods in ERP Analysis

52

 

HBI Reference Database

s3.

 

Go/No-Go Task

s3

 

Methodology of Decomposition of Collection of ERPs into Independent Components

56

 

Methodology of Decomposition of Individual ERPs into Independent Components

57

 

Independent Components in Go/No-Go Task

58

 

Application of ERP/ICA Methodology for ADHD - Response Inhibition

65

 

ERPs as Indexes of Neurofeedback Efficacy

66

 

ERPs as Index of tDCs Effect

70

 

References

73

4

EEG Vigilance and Phenotypes in Neuropsychiatry: Implications for Intervention   Martijn Arns, Jay Gunkelman, Sebastian Olbrich, Christian Sander, and Ulrich Hegerl

79

 

Introduction

79

 

History of EEG Research in ADHD and Depression

83

 

EEG and qEEG: Models and Theory

94

 

EEG Vigilance Model

95

 

EEG Phenotype Model

105

 

EEG Phenotype vs. EEG Vigilance: Towards a Coherent Model?

112

 

Acknowledgments

115

 

References

115

PART TWO

ENDOGENOUS NEUROMODULATION STRATEGIES

125

5

Neurofeedback with Children with Attention Deficit Hyperactivity Disorder: A Randomized Double-Blind Placebo-Controlled Study   Roger J. deBeus and David A. Kaiser

127

 

Introduction

128

 

Method

132

 

Results

139

 

Discussion

141

 

Conclusions

148

 

Acknowledgments

148

 

References

148

6

Emerging Empirical Evidence Supporting Connectivity-Guided Neurofeedback for Autistic Disorders   Robert Coben and Lori A. Wagner

153

 

Introduction

153

 

Major Treatments for ASD: An Overview

155

 

Neurofeedback for ASD

168

 

qEEG Evaluation and ASD

170

 

Discussion

175

 

References

176

7

Neurofeedback and Epilepsy   Gabriel Tan, D. Corydon Hammond, Jonathan Walker, Ellen Broelz, and Ute Strehl

183

 

Introduction

183

 

Research Synopsis

184

 

Clinical Protocols

186

 

Individualizing Neurofeedback Based on qEEG Findings

187

 

Low Energy Neurofeedback System (LENS)

198

 

Observations and Implications for Future Direction

200

 

References

201

8

Feedback of Slow Cortical Potentials: Basics, Application, and Evidence   Sarah Wyckoff and Ute Strehl

205

 

Basics

206

 

Technical and Training Requirements

209

 

Diagnosis and Evaluation

215

 

Evidence Base and Indications

217

 

Conclusion

222

 

References

222

9

Real-Time Regulation and Detection of Brain States from fMRI Signals   Ranganatha Sitaram, Sangkyun Lee, Sergio Ruiz, and Niels Birbaumer

227

 

Introduction

227

 

Historical Development of Real-Time fMRI

228

 

Overview of the fMRIBCI System

232

 

fMRA-BCI in Research and Clinical Treatment

238

 

Conclusions

248

 

References

249

PART THREE

EXOGENOUS NEUROMODULATION STRATEGIES

255

10

Repetitive Transcranial Magnetic Stimulation in Depression: Protocols, Mechanisms, and New Developments   Desiree Spronk, Martijn Arns, and Paul B. Fitzgerald

257

 

Introduction

257

 

Protocols

261

 

Mechanisms of rTMS Treatment in Depression

270

 

New Developments

277

 

Acknowledgments

282

 

References

283

11

Transcranial Magnetic Stimulation for Tinnitus   Berthold Langguth and Dirk de Ridder

293

 

Tinnitus: Introduction

293

 

Transcranial Magnetic Stimulation

296

 

Conclusion

311

 

References

312

12

Neurophysiological Effects of Transcranial Direct Current Stimulation   Jay S. Reidler, Soroush Zaghi, and Felipe Fregni

319

 

Introduction

319

 

The Growing Field of Brain Stimulation

320

 

Electrophysiology of tDCS

323

 

Neurochemistry of tDCS

337

 

Safety Considerations for tDCS

340

 

Conclusions and Future Directions

341

 

Acknowledgment

344

 

References

344

PART FOUR

MECHANISM OF CHANGE AND LONG-TERM CONSOLIDATION: BEGINNING EVIDENCE

351

13

Functional Neuroimaging Evidence Supporting Neurofeedback in ADHD   Johanne Lévesque and Mario Beauregard

353

 

Introduction

353

 

Biological Basis of ADHD

354

 

Impact of Neurofeedback Training on the Neural Substrates of Selective Attention and Response Inhibition in Children with ADHD

361

 

Putative Neural Mechanisms Underlying the Effects of Neurofeedback in ADHD

366

 

Conclusion

368

 

References

369

14

The Immediate Effects of EEG Neurofeedback on Cortical Excitability and Synchronization   Tomas Ros and John H. Gruzelier

381

 

Introduction

381

 

Methods

383

 

Results

387

 

Discussion

395

 

References

399

15

Enduring Effects of Neurofeedback in Children   Robert Coben, Martijn Arns, and Mirjam E.J. Kouijzer

403

 

Introduction

403

 

Neurofeedback as a Treatment for Children with ADHD

405

 

Long-Term Effects of Neurofeedback

406

 

Neurofeedback as a Treatment for Children with ASD

408

 

Enduring Behavioral and Neuropsychological Benefits of Neurofeedback in ASD

413

 

Discussion

417

 

Acknowledgment

419

 

References

419

 

Index

423