Table of Contents

 

 

 

PART A

FUNDAMENTALS

 

Chapter 1

Structure of Matter   Jean Chavaudra

5

Chapter 2

Radioactivity   Jean Chavaudra

19

Chapter 3

Interactions of Charged Particles with Matter   Alan Nahum

35

Chapter 4

Interactions of Photons with Matter   David Dance and Gudrun Alm Carlsson

57

Chapter 5

The Monte Carlo Simulation of Radiation Transport   Alex Bielajew

75

Chapter 6

Principles and Basic Concepts in Radiation Dosimetry   Alan Nahum

89

 

References

117

PART B

RADIOBIOLOGY

 

Chapter 7

Radiobiology of Tumours   Gordon Steel (with Don Chapman and Alan Nahum)

127

Chapter 8

Radiobiology of Normal Tissues   Gordon Steel

149

Chapter 9

Dose Fractionation in Radiotherapy   Gordon Steel (with Alan Nahum)

163

 

References

179

PART C

EQUIPMENT

 

Chapter 10

Kilovoltage X-Ray Units   Tony Greener

187

Chapter 11

Linear Accelerators   Les Loverock (with Philip Mcyles, Alan McKenzie, David Thwaites and Peter Williams)

197

Chapter 12

Cobalt Machines   John Sounders

241

Chapter 13

Simulators   Jean-Claude Rosenwald

251

Chapter 14

Portal Imaging Devices   Cephas Mubata

261

 

References

271

PART D

DOSE MEASUREMENT

 

Chapter 15

Ionisation Chambers   Pedro Andrea, Alan Nahum, and David Thwaites

279

Chapter 16

Radiothermoluminescent Dosimeters and Diodes   Ginette Marinello

303

Chapter 17

Radiation Sensitive Films and Gels   Mark Oldham

321

Chapter 18

Absolute Dose Determination Under Reference Conditions   Pedro Andrea and Alan Nahum (with David Thwaites)

333

Chapter 19

Relative Dose Measurements and Commissioning   Ivan Rosenberg

367

Appendix D

Supplementary Details on Codes of Practice for Absolute Dose Determination   Pedro Andreo and Alan Nahum

385

 

References

415

PART E

CLINICAL BEAMS

 

Chapter 20

From Measurements to Calculations   Philip Mayles

433

Chapter 21

Kilovoltage X-Rays   Philip Mayles

439

Chapter 22

Megavoltage Photon Beams   Philip Mayles and Peter Williams

451

Chapter 23

Manual Dose Calculations in Photon Beams   Ivan Rosenberg

483

Chapter 24

Electron Beams   David Thwaites and Alan McKenzie

519

 

References

539

PART F

PATIENT DOSE COMPUTATION METHODS

 

Chapter 25

Principles of Patient Dose Computation   Jean-Claude Rosenwald

549

Chapter 26

Patient Dose Computation for Photon Beams   Jean-Claude Rosenwald, Ivan Rosenberg, and Glyn Shentall (with David McKay)

559

Chapter 27

Patient Dose Computation for Electron Beams   Alan Nahum

587

Chapter 28

Monte-Carlo Based Patient Dose Computation   Alan Nahum

603

 

References

621

PART G

TREATMENT PLANNING

 

Chapter 29

Target Definition   Anthony Neal

637

Chapter 30

Patient Data Acquisition   Anthony Neal

647

Chapter 31

Magnetic Resonance Imaging in Treatment Planning   Vincent Khoo

657

Chapter 32

Beam Definition—Virtual Simulation   Vibeke Nordmark Hansen

669

Chapter 33

Photon-Beam Treatment Planning Techniques   Peter Childs and Christine Lord

681

Chapter 34

Electron-Beam Treatment Planning Techniques   Alan McKenzie and David Thwaites

701

Chapter 35

Dose Evaluation of Treatment Plans   Margaret Bidmead and Jean-Claude Rosenwald

719

Chapter 36

Biological Evaluation of Treatment Plans   Alan Nahum and Gerald Kutcher

731

 

References

773

PART H

QUALITY ASSURANCE

 

Chapter 37

Rationale and Management of the Quality System   Philip Mayles and David Thwaites (with Jean-Claude Rosenwald)

793

Chapter 38

Quality Control of Megavoltage Equipment   Edwin Aird, Philip Mayles, and Cephas Mubata

809

Chapter 39

Quality Assurance of the Treatment Planning Process   Jean-Claude Rosenwald

841

Chapter 40

Quality Control of Treatment Delivery   Philip Evans and Ginette Marinello

867

Chapter 41

Recording and Verification—Networking   Margaret Bidmead

897

Chapter 42

Data Communication with DICOM   John Soge, John Brunt, and Philip Mayles

909

 

References

921

PART I

SPECIAL TECHNIQUES

 

Chapter 43

Conformal and Intensity-Modulated Radiotherapy   Steve Webb

943

Chapter 44

Intensity-Modulated Radiotherapy: Practical Aspects   C.-M. Charlie Ma (with Helen Mayles and Philip Mayles)

975

Chapter 45

Stereotactic Techniques   Jim Warrington

987

Chapter 46

Proton Beams in Radiotherapy   Alejandro Mazal

1005

Chapter 47

Total Body Irradiation   Philip Mayles (with Ginette Marinello)

1033

Chapter 48

Total Skin Electron Irradiation   David Thwaites and Alan McKenzie (with Ginette Marinello)

1043

Chapter 49

High-LET Modalities   Roland Sabattier, Oliver Jäkel, and Alejandro Mazal

1053

 

References

1069

PART J

BRACHYTHERAPY

 

Chapter 50

Clinical Introduction to Brachytherapy   Peter Blake

1093

Chapter 51

Calibration and Quality Assurance of Brachytherapy Sources   Colin Jones

1101

Chapter 52

Afterloading Equipment for Brachytherapy   Margaret Bidmead and Colin Jones

1117

Chapter 53

Dose Calculation for Brachytherapy Sources   Philip Mayles

1131

Chapter 54

Brachytherapy Treatment Planning   Margaret Bidmead and Dorothy Ingham (with Jean-Claude Rosenwald)

1141

Chapter 55

Radiobiology of Brachytherapy   Roger Dale

1181

 

References

1193

PART K

THERAPY WITH UNSEALED SOURCES

 

Chapter 56

Dosimetry of Unsealed Sources   Maggie Flower and Jamal Zweit

1205

Chapter 57

Radionuclide Selection for Unsealed Source Therapy   Maggie Flower, Jamal Zweit, and Mark Atthey

1211

Chapter 58

Radiopharmaceutical Targeting for Unsealed Source Therapy   Maggie Flower and Jamid Zweit

1219

 

References

1225

PART L

RADIATION PROTECTION IN RADIOTHERAPY

 

Chapter 59

Theoretical Background to Radiation Protection   Mike Rosenbloom

1233

Chapter 60

Radiation Protection Regulation   Mike Rosenbloom and Philip Mayles

1245

Chapter 61

Practical Radiation Protection in Radiotherapy   Mike Rosenbloom (with Philip Mayles)

1257

Appendix L

Radiation Protection Regulation in the United Kingdom   Philip Mayles (with Mike Rosenbloom)

1285

 

References

1297

PART M

REFERENCE DATA

 

Tables M.1

Physical Constants and Useful Data   Jean-Claude Rosenwald

1305

Tables M.2

Electron Stopping Powers, Ranges, and Radiation Yields   Alan Nahum

1308

Tables M.3

Photon Interaction Coefficients   Alan Nahum

1335

Tables M.4

Radioactive Nuclides Used in Radiotherapy   Philip Mayles

1388

 

References

1395

 

Index

1397