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Table of Contents


	Preface	xi
PART I	UNDERSTANDING BLOOD AND THE CIRCULATORY SYSTEM
Chapter 1	Blood Function and Composition	3
Chapter 2	Blood Types	15
Section 2.1	Introduction to Blood Types	16
Section 2.2	Blood Types in the United States	19
Chapter 3	Donating and Preserving Blood	21
Section 3.1	Frequently Asked Questions About Blood Donation	22
Section 3.2	Tips for a Good Donation Experience	24
Section 3.3	Apheresis	26
Section 3.4	Cord Blood Banking	28
Chapter 4	Maintaining a Healthy Circulatory System	31
Chapter 5	How Aging Affects the Heart and Blood Vessels	37
PART II	DIAGNOSING AND TREATING BLOOD AND CIRCULATORY DISORDERS
Chapter 6	Blood Tests	45
Section 6.1	Blood Typing	46
Section 6.2	Complete Blood Count	50
Section 6.3	Fibrinogen Test	54
Section 6.4	Reticulocyte Count	57
Chapter 7	Bone Marrow Tests	61
Chapter 8	Bleeding and Clotting Tests	65
Section 8.1	Bleeding Time	66
Section 8.2	Partial Thromboplastin Time	68
Chapter 9	Tests Used in the Assessment of Vascular Disease	71
Chapter 10	Commonly Used Medications for Cardiovascular Health	77
Section 10.1	Facts About Using Aspirin	78
Section 10.2	Anticoagulants and Antiplatelet Agents	81
Section 10.3	Using Coumadin Safely	84
Chapter 11	Commonly Used Medications for Anemia	91
Section 11.1	Iron Supplements	92
Section 11.2	Erythropoiesis-Stimulating Agents	95
Chapter 12	Blood Transfusion	99
Chapter 13	Bone Marrow and Stem Cell Transplants	107
Chapter 14	Chelation Therapy: A Controversial Treatment Approach	117
PART III	BLOOD DISORDERS
Chapter 15	Anemia	127
Section 15.1	Anemia: An Overview	128
Section 15.2	Anemia of Chronic Disease	135
Section 15.3	Aplastic Anemia	138
Section 15.4	Fanconi Anemia	145
Section 15.5	Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency	154
Section 15.6	Hemoglobin C Disease	157
Section 15.7	Hemoglobin E Disease	159
Section 15.8	Iron-Deficiency Anemia	162
Section 15.9	Pernicious (Megaloblastic) Anemia	165
Section 15.10	Sickle Cell Disease	167
Section 15.11	Spherocytosis	173
Section 15.12	Thalassemia	176
Chapter 16	Hemochromatosis	181
Chapter 17	Leukemia	187
Section 17.1	Acute Lymphocytic Leukemia	188
Section 17.2	Chronic Lymphocytic Leukemia	196
Section 17.3	Acute Myelogenous Leukemia	203
Section 17.4	Chronic Myelogenous Leukemia	212
Section 17.5	Hairy Cell Leukemia	218
Chapter 18	Lymphoma	225
Section 18.1	Hodgkin Lymphoma	226
Section 18.2	Non-Hodgkin Lymphoma	233
Section 18.3	Waldenstr�m Macroglobulinemia	244
Chapter 19	Myeloproliferative Disorders	249
Section 19.1	Idiopathic Myelofibrosis	250
Section 19.2	Myelodysplastic Syndrome	256
Section 19.3	Polycythemia Vera	260
Section 19.4	Thrombocythemia and Thrombocytosis	267
Chapter 20	Plasma Cell Disorders	277
Section 20.1	Amyloidosis	278
Section 20.2	Cryoglobulinemia	282
Section 20.3	Monoclonal Gammopathy of Undetermined Significance	286
Section 20.4	Multiple Myeloma	287
Chapter 21	Rh Disease	291
Chapter 22	White Blood Cell Disorders	295
Section 22.1	Hypereosinophilic Syndrome	296
Section 22.2	Histiocytosis	300
Section 22.3	Lymphocytopenia	305
Section 22.4	Neutropenia	309
PART IV	BLEEDING AND CLOTTING DISORDERS
Chapter 23	What are Hereditary Bleeding and Clotting Disorders?	317
Chapter 24	Hemophilia	323
Chapter 25	Von Willebrand Disease	335
Chapter 26	Factor V Leiden	341
Chapter 27	Factor Deficiencies	345
Chapter 28	Hereditary Hemorrhagic Telangiectasia	353
Chapter 29	Bruises: When to See a Doctor	355
Chapter 30	Antiphospholipid Antibody Syndrome	359
Chapter 31	Disseminated Intravascular Coagulation	365
Chapter 32	Hypercoagulation	371
Section 32.1	Excessive Blood Clotting	372
Section 32.2	Deep Vein Thrombosis	375
Section 32.3	Pulmonary Embolism	380
Section 32.4	Preventing and Treating Blood Clots	385
Chapter 33	Thrombocytopenia	389
Chapter 34	Idiopathic Thrombocytopenic Purpura	397
Chapter 35	Thrombotic Thrombocytopenic Purpura	403
Chapter 36	Thrombophilia	407
PART V	CIRCULATORY DISORDERS
Chapter 37	Aneurysm	413
Chapter 38	Aortic Dissection	421
Chapter 39	Arteritis	427
Section 39.1	Takayasu Arteritis	428
Section 39.2	Temporal Arteritis	430
Chapter 40	Atherosclerosis	433
Chapter 41	Blood Pressure Disorders	441
Section 41.1	Hypertension (High Blood Pressure)	442
Section 41.2	Portal Hypertension	446
Section 41.3	Preeclampsia	449
Section 41.4	Renovascular Hypertension	452
Section 41.5	Hypotension (Low Blood Pressure)	454
Section 41.6	Shock	465
Section 41.7	Syncope (Fainting)	468
Chapter 42	Carotid Artery Disease	471
Chapter 43	Coronary Artery and Heart Disease	475
Section 43.1	Coronary Artery Disease	476
Section 43.2	Angina	485
Section 43.3	Heart Attack	488
Chapter 44	Fibromuscular Dysplasia	493
Chapter 45	Klippel-Tr�naunay Syndrome	499
Chapter 46	Peripheral Vascular Disease	503
Section 46.1	Buerger Disease (Thromboangiitis Obliterans)	504
Section 46.2	Claudication	506
Section 46.3	Critical Limb Ischemia	509
Section 46.4	Erythromelalgia	512
Section 46.5	Peripheral Artery Disease	516
Section 46.6	Raynaud Phenomenon	521
Chapter 47	Renovascular Artery Stenosis and Thrombosis	525
Chapter 48	Sepsis	531
Chapter 49	Stroke	535
Chapter 50	Vascular Birthmarks: Hemangiomas and Vascular Malformations	541
Chapter 51	Vasculitis	543
Chapter 52	Venous Disorders	555
Section 52.1	Arteriovenous Fistula	556
Section 52.2	Chronic Venous Insufficiency	558
Section 52.3	Thrombophlebitis	560
Section 52.4	Varicose Veins and Spider Veins	563
PART VI	ADDITIONAL HELP AND INFORMATION
Chapter 53	Glossary of Terms Related to Blood and Circulatory Disorders	573
Chapter 54	Directory of Resources Related to Blood and Circulatory Disorders	579
	Index	589