Table of Contents

 

 

 

 

Preface

xiii

PART I

CANCER RISK FACTORS AND CANCER PREVENTION

 

Chapter 1

Questions and Answers About Cancer

3

Chapter 2

Cancer Statistics

9

Section 2.1

Understanding Statistics on Incidence, Prevalence, and Mortality

10

Section 2.2

The Role Statistics Play in Predicting a Patient’s Prognosis

14

Section 2.3

Incidence, Mortality, and Survival Rates for Common Cancers

17

Chapter 3

Cancer Health Disparities

37

Chapter 4

Lifestyle Issues and Cancer Risk

51

Section 4.1

Tobacco Use and Cancer Risk

52

Section 4.2

Facts About Alcohol Use and Cancer Risk

60

Section 4.3

Questions and Answers About Obesity and Cancer Risk

63

Section 4.4

The Roles of Exercise and Stress Management in Reducing Cancer Risk

70

Section 4.5

Sun Exposure and Cancer Risk

76

Section 4.6

Indoor Tanning and Cancer Risk

82

Chapter 5

Hereditary Cancer Risks

85

Chapter 6

Infectious Diseases and Cancer Risk

91

Section 6.1

Human Papillomaviruses and Cancer: Questions and Answers

92

Section 6.2

HIV Infection and Cancer Risk

96

Section 6.3

Kaposi Sarcoma-Associated Herpesvirus

99

Section 6.4

Hepatitis Viruses and Cancer Risk

101

Section 6.5

Human T-Lymphotropic Virus Type 1 (HTLV1) and Cancer Risk

103

Section 6.6

Epstein-Barr Virus and Cancer Risk

104

Section 6.7

Helicobacter Pylori and Cancer Risk

106

Chapter 7

Hormonal Therapies and Cancer Risk

115

Section 7.1

Oral Contraceptives and Cancer Risk

116

Section 7.2

Menopausal Hormone Replacement Therapy Use and Cancer

121

Section 7.3

Risk of Ovarian Cancer from Hormone Therapy Confirmed

130

Section 7.4

Diethylstilbestrol (DES) and Cancer Risk

131

Chapter 8

Radiation and Cancer Risk

137

Section 8.1

The Difference Between Ionizing and Non-Ionizing Radiation

138

Section 8.2

How Radiation Affects Cancer Risk

141

Section 8.3

Radon and Cancer

145

Section 8.4

Medical X-Rays: Benefits and Risks

149

Section 8.5

Iodine-131 and Cancer Risk

151

Section 8.6

Magnetic Field Exposure and Cancer

158

Chapter 9

Environmental Carcinogens

163

PART II

COMMON TYPES OF CANCER

 

 

Cancers Affecting the Brain and Central Nervous System

 

Chapter 10

Brain Tumors

173

Chapter 11

Childhood Brain and Spinal Cord Tumors

185

Chapter 12

Neuroblastoma

197

Chapter 13

Primary Central Nervous System Lymphoma

209

 

Cancers Affecting the Endocrine System

 

Chapter 14

Pituitary Tumors

217

Chapter 15

Thyroid Cancer

229

Chapter 16

Parathyroid Cancer

245

Chapter 17

Adrenocortical Carcinoma

253

Chapter 18

Islet Cell Tumors

261

 

Cancers Affecting the Eyes, Mouth, and Neck

 

Chapter 19

Retinoblastoma

275

Chapter 20

Oral Cancer

283

Chapter 21

Laryngeal Cancer

293

 

Cancers that Affect the Lungs

 

Chapter 22

Lung Cancer: An Overview

309

Chapter 23

Small Cell Lung Cancer

319

Chapter 24

Non-Small Cell Lung Cancer

325

Chapter 25

Malignant Mesothelioma

337

 

Cancers Affecting the Digestive Tract

 

Chapter 26

Esophageal Cancer

345

Chapter 27

Stomach Cancer

359

Chapter 28

Gallbladder Cancer

371

Chapter 29

Pancreatic Cancer

379

Chapter 30

Liver Cancer

389

Chapter 31

Extrahepatic Bile Duct Cancer

401

Chapter 32

Gastrointestinal Carcinoid Tumors

409

Chapter 33

Small Intestine Cancer

417

Chapter 34

Colon Cancer

423

Chapter 35

Rectal Cancer

435

Chapter 36

Anal Cancer

445

 

Cancers Affecting the Urinary Tract

 

Chapter 37

Kidney Cancers

451

Section 37.1

Renal Cell Cancer

452

Section 37.2

Wilms Tumor and Other Childhood Kidney Tumors

458

Chapter 38

Transitional Cell Cancer of the Renal Pelvis and Ureter

469

Chapter 39

Urethral Cancer

475

Chapter 40

Bladder Cancer

483

 

Cancers Affecting the Breasts and Reproductive Organs

 

Chapter 41

Breast Cancer

491

Chapter 42

Gynecological Cancers

513

Section 42.1

Cervical Cancer

514

Section 42.2

Endometrial Cancer

519

Section 42.3

Gestational Trophoblastic Tumors

522

Section 42.4

Ovarian Epithelial Cancer

525

Section 42.5

Uterine Sarcoma

529

Section 42.6

Vaginal Arid Vulvar Cancers

532

Section 42.7

Common Procedures for Cancers of the Female Reproductive Organs

539

Chapter 43

Andrological Cancers

555

Section 43.1

Penile Cancer

556

Section 43.2

Prostate Cancer

563

Section 43.3

Testicular Cancer

576

 

Cancers Affecting the Blood Cells and Immune System

 

Chapter 44

Leukemia

585

Chapter 45

Lymphoma

601

Section 45.1

Hodgkin Lymphoma

602

Section 45.2

Non-Hodgkin Lymphoma

613

Chapter 46

Multiple Myeloma

623

Chapter 47

Myelodysplastic and Myeloproliferative Diseases

633

Chapter 48

Thymoma and Thymic Carcinoma

641

 

Cancers Affecting the Skin and Bones

 

Chapter 49

Melanoma

649

Chapter 50

Non-Melanoma Skin Cancer

659

Chapter 51

Merkel Cell Carcinoma

671

Chapter 52

Bone Cancers

679

Section 52.1

Questions and Answers About Bone Cancers

680

Section 52.2

Osteosarcoma and Bone Fibrous Histiocytoma

685

Section 52.3

Ewing Sarcoma Family of Tumors

694

 

Cancers Affecting Other or Multiple Body Systems

 

Chapter 53

Soft Tissue Sarcomas

703

Section 53.1

Childhood Soft Tissue Sarcoma

704

Section 53.2

Adult Soft Tissue Sarcoma

717

Section 53.3

Synovial Sarcoma

722

Chapter 54

Germ Cell Tumors

725

Section 54.1

Ovarian Germ Cell Tumors

726

Section 54.2

Extragonadal Germ Cell Tumors

733

Section 54.3

Childhood Extracranial Germ Cell Tumors

739

Chapter 55

Carcinoma of Unknown Primary Origin

749

PART III

CANCER-RELATED TESTS AND TREATMENTS

 

Chapter 56

Cancer Screening and Early Detection

755

Chapter 57

Common Medical Procedures and Tests

765

Section 57.1

Medical Tests and Procedures for Cancer Patients

766

Section 57.2

Cancer Imaging

770

Section 57.3

Questions and Answers About Computed Tomography (CT)

777

Section 57.4

Tumor Markers

780

Chapter 58

Surgical Procedures and Cancer

785

Section 58.1

What You Need to Know About Surgery

786

Section 58.2

Lasers in Cancer Treatment

792

Section 58.3

Cryosurgery in Cancer Treatment

794

Chapter 59

Chemotherapy

799

Chapter 60

Radiation Therapy

809

Chapter 61

Bone Marrow Transplantation and Peripheral Blood Stem Cell Transplantation

823

Chapter 62

Biological Therapies

831

Chapter 63

Molecularly Targeted Therapies

839

Chapter 64

Photodynamic Therapy for Cancer

849

Chapter 65

Cancer and Complementary and Alternative Medicine (CAM)

853

Section 65.1

Thinking About CAM

854

Section 65.2

Dietary Supplements and Cancer Treatment

862

PART IV

RECURRENT AND ADVANCED CANCER

 

Chapter 66

Metastatic Cancer

867

Chapter 67

Recurrent Cancer

871

Chapter 68

End-of-Life Care

883

PART V

CANCER RESEARCH

 

Chapter 69

How to Find a Cancer Treatment Trial

897

Chapter 70

Access to Investigational Drugs

911

Chapter 71

Cancer Vaccines

917

Chapter 72

Gene Therapy for Cancer

931

Chapter 73

Proton Therapy

939

Chapter 74

The Potential of Nanotechnology in Cancer Care

943

PART VI

ADDITIONAL HELP AND INFORMATION

 

Chapter 75

A Glossary of Cancer-Related Terms

951

Chapter 76

National Organizations Offering Cancer-Related Services

1013

Chapter 77

How to Find Resources in Your Own Community if you have Cancer

1029

Chapter 78

Beware of Online Cancer Fraud

1035

 

Index

1041