Table of Contents

 

 

 

Introduction

A View of the Past: Exercise Physiology—Roots and Historical Perspectives   Dr. Charles Tipton

xvii

PART ONE

EXERCISE PHYSIOLOGY

1

Section 1

Nutrition: The Base for Human Performance   Interview with Dr. David L. Costill

3

Chapter 1

Carbohydrates, Lipids, and Proteins

7

Part 1

Carbohydrates

8

 

Kinds and Sources of Carbohydrates

8

 

Recommended Intake of Carbohydrates

13

 

Role of Carbohydrates in the Body

13

 

Carbohydrate Dynamics in Exercise

16

Part 2

Lipids

20

 

The Nature of Lipids

20

 

Kinds and Sources of Lipids

20

 

Recommended Lipid Intake

26

 

Role of Lipid in the Body

27

 

Fat Dynamics during Exercise

28

Part 3

Proteins

31

 

The Nature of Proteins

31

 

Kinds of Protein

31

 

Recommended Protein Intake

33

 

Role of Protein in the Body

35

 

Dynamics of Protein Metabolism

37

 

Nitrogen Balance

37

 

Protein Dynamics in Exercise and Training

39

Chapter 2

Vitamins, Minerals, and Water

42

Part 1

Vitamins

43

 

The Nature of Vitamins

43

 

Kinds of Vitamins

43

 

Role of Vitamins

43

 

Defining Nutrient Needs

45

 

Exercise, Free Radicals, and Antioxidants

51

 

Vitamin Supplements: The Competitive Exercise Edge?

53

Part 2

Minerals

56

 

The Nature of Minerals

56

 

Role of Minerals in the Body

56

 

Calcium

56

 

The Female Athlete Triad: Unexpected Problem for Women Who Train Intensely

63

 

Phosphorus

65

 

Magnesium

65

 

Iron

67

 

Sodium, Potassium, and Chlorine

71

 

Minerals and Exercise Performance

72

Part 3

Water

75

 

The Body’s Water Content

75

 

Water Balance: Intake versus Output

77

 

Water Requirement in Exercise

78

Chapter 3

Optimal Nutrition for Exercise

81

 

Nutrient Intake Among the Physically Active

82

 

Mypyramid: The Essentials of Good Nutrition

87

 

Exercise and Food Intake

90

 

Precompetition Meal

94

 

Carbohydrate Feedings Prior To, During, and in Recovery from Exercise

97

 

Glucose Feedings, Electrolytes, and Water Uptake

101

Section 2

Energy for Physical Activity   Dr. John O. Holloszy

107

Chapter 4

Energy Value of Food

111

 

Measurement of Food Energy

112

Chapter 5

Introduction to Energy Transfer

118

 

Energy—The Capacity for Work

119

 

Interconversions of Energy

121

 

Biologic Work in Humans

123

 

Factors that Affect the Rate of Bioenergetics

124

 

Hydrolysis and Condensation: The Basis for Digestion and Synthesis

128

Chapter 6

Energy Transfer in the Body

134

Part 1

Phosphate Bond Energy

135

 

Adenosine Triphosphate: The Energy Currency

135

 

Phosphocreatine: The Energy Reservoir

138

 

Cellular Oxidation

138

 

Oxygen’s Role in Energy Metabolism

142

Part 2

Energy Release from Macronutrients

142

 

Energy Release from Carbohydrate

145

 

Energy Release from Fat

153

 

Energy Release from Protein

157

 

The Metabolic Mill: Interrelationships Among Carbohydrate, Fat, and Protein Metabolism

159

Chapter 7

Energy Transfer during Exercise

162

 

Immediate Energy: The ATP-PCR System

163

 

Short-Term Energy: The Lactic Acid System

163

 

Long-Term Energy: The Aerobic System

164

 

Energy Spectrum of Exercise

168

 

Oxygen Consumption during Recovery

169

Chapter 8

Measurement of Human Energy Expenditure

178

 

Measuring the Body’s Heat Production

179

 

Doubly Labeled Water Technique

185

 

Respiratory Quotient

186

 

Respiratory Exchange Ratio

190

Chapter 9

Human Energy Expenditure during Rest and Physical Activity

192

Part 1

Energy Expenditure at Rest

193

 

Basal and Resting Metabolic Rate

193

 

Metabolic Size Concept

193

 

Comparing Metabolic Rates in Humans

194

 

Factors that Affect Energy Expenditure

197

Part 2

Energy Expenditure During Physical Activity

200

 

Classification of Physical Activities by Energy Expenditure

200

 

The Met

200

 

Daily Rates of Average Energy Expenditure

201

 

Energy Cost of Household, Industrial, and Recreational Activities

201

 

Heart Rate to Estimate Energy Expenditure

203

Chapter 10

Energy Expenditure during Walking, Jogging, Running, and Swimming

206

 

Gross versus Net Energy Expenditure

207

 

Economy of Human Movement and Mechanical Efficiency

207

 

Energy Expenditure during Walking

209

 

Energy Expenditure during Running

212

 

Swimming

220

Chapter 11

Individual Differences and Measurement of Energy Capacities

225

 

Specificity versus Generality of Metabolic Capacity and Exercise Performance

226

 

Overview of Energy-Transfer Capacity during Exercise

226

 

Anaerobic Energy Transfer: The Immediate and Short-Term Energy Systems

227

 

Aerobic Energy: The Long-Term Energy System

234

Section 3

Aerobic Systems of Energy Delivery and Utilization   Dr. Loring B. Rowell

249

Chapter 12

Pulmonary Structure and Function

253

 

Surface Area and Gas Exchange

254

 

Anatomy of Ventilation

254

 

Mechanics of Ventilation

255

 

Lung Volumes and Capacities

258

 

Lung Function, Aerobic Fitness, and Exercise Performance

261

 

Pulmonary Ventilation

263

 

Variations from Normal Breathing Patterns

265

 

The Respiratory Tract during Cold-Weather Exercise

266

Chapter 13

Gas Exchange and Transport

270

Part 1

Gaseous Exchange in the Lungs and Tissues

271

 

Concentrations and Partial Pressures of Respired Gases

271

 

Movement of Gas in Air and Fluids

272

 

Gas Exchange in the Lungs and Tissues

273

Part 2

Oxygen Transport

275

 

Transport of Oxygen in the Blood

275

Part 3

Carbon Dioxide Transport

282

 

Carbon Dioxide Transport in the Blood

282

Chapter 14

Dynamics of Pulmonary Ventilation

286

Part 1

Regulation of Pulmonary Ventilation

287

 

Ventilatory Control

287

 

Regulation of Ventilation during Exercise

289

Part 2

Pulmonary Ventilation During Exercise

291

 

Ventilation and Energy Demands in Exercise

291

 

Energy Cost of Breathing

296

 

Does Ventilation Limit Aerobic Power and Endurance?

298

Part 3

Acid-Base Regulation

300

 

Buffering

300

 

Physiologic Buffers

301

 

Effects of Intense Exercise

302

Chapter 15

The Cardiovascular System

303

 

Cardiovascular System Components

304

 

Hypertension

315

 

Blood Pressure Response to Exercise

317

 

The Heart’s Blood Supply

319

 

Myocardial Metabolism

322

Chapter 16

Cardiovascular Regulation and Integration

324

 

Intrinsic Regulation of Heart Rate

325

 

Extrinsic Regulation of Heart Rate and Circulation

328

 

Distribution of Blood

333

 

Integrative Exercise Response

335

 

Exercising After Cardiac Transplantation

335

Chapter 17

Functional Capacity of the Cardiovascular System

340

 

Cardiac Output

341

 

Cardiac Output at Rest

342

 

Cardiac Output during Exercise

343

 

Cardiac Output Distribution

346

 

Cardiac Output and Oxygen Transport

347

 

Cardiovascular Adjustments to Upper-Body Exercise

351

Chapter 18

Skeletal Muscle: Structure and Function

353

 

Gross Structure of Skeletal Muscle

354

 

Skeletal Muscle Ultrastructure

357

 

Muscle Fiber Alignment

360

 

Actin-Myosin Orientation

363

 

Chemical and Mechanical Events during Muscle Action and Relaxation

364

 

Muscle Fiber Type

371

 

Genes that Define Skeletal Muscle Phenotype

374

 

Fiber Type Differences Among Athletic Groups

374

Chapter 19

Neural Control of Human Movement

376

 

Neuromotor System Organization

377

 

Nerve Supply to Muscle

385

 

Motor Unit Functional Characteristics

390

 

Receptors in Muscles, Joints, and Tendons: The Proprioceptors

393

Chapter 20

The Endocrine System: Organization and Acute and Chronic Responses to Exercise

400

 

Endocrine System Overview

401

 

Endocrine System Organization

401

 

Resting and Exercise-Induced Endocrine Secretions

407

 

Gonadal Hormones

417

 

Exercise Training and Endocrine Function

430

 

Resistance Training and Endocrine Function

437

 

Opioid Peptides and Physical Activity

439

 

Physical Activity, Infectious Illness, Cancer, and Immune Response

439

PART TWO

APPLIED EXERCISE PHYSIOLOGY

445

Section 4

Enhancement of Energy Transfer Capacity   Dr. Bengt Saltin

447

Chapter 21

Training for Anaerobic and Aerobic Power

451

 

Exercise Training Principles

452

 

Physiologic Consequences of Exercise Training

457

 

Anaerobic System Changes with Training

458

 

Aerobic System Changes with Training

458

 

Factors that Affect Aerobic Training Responses

470

 

American College of Sports Medicine and American Heart Association Updated Fitness Guidelines and Recommendations

475

 

How Long Before Improvements Occur?

476

 

Maintenance of Aerobic Fitness Gains

478

 

Training Methods

479

 

Overtraining: Too Much of a Good Thing

483

 

Exercising during Pregnancy

485

Chapter 22

Muscular Strength: Training Muscles to Become Stronger

490

Part 1

Strength Measurement and Resistance Training

491

 

Measurement of Muscle Strength

492

 

Gender Differences in Muscle Strength

495

 

Training Muscles to Become Stronger

498

Part 2

Structural and Functional Adaptations to Resistance Traininc

519

 

Factors that Modify the Expression of Human Strength

519

 

Comparative Training Responses in Men and Women

526

 

Detraining

527

 

Metabolic Stress of Resistance Training

527

 

Circuit Resistance Training

528

 

Muscle Soreness and Stiffness

528

Chapter 23

Special Aids to Exercise Training and Performances

533

 

An Increasing Challenge to Fair Competition

534

 

A Need to Critically Evaluate the Scientific Evidence

538

 

On the Horizon

540

 

Pharmacologic Agents

541

 

Nonpharmacologic Approaches

566

Section 5

Exercise Performance and Environmental Stress   Dr. Barbara Drinkwater

587

Chapter 24

Exercise at Medium and High Altitude

591

 

The Stress of Altitude

592

 

Acclimatization

596

 

Metabolic, Physiologic, and Exercise Capacities at Altitude

604

 

Altitude Training and Sea-Level Performance

606

 

Combine Altitude Stay with Low-Altitude Training

608

Chapter 25

Exercise and Thermal Stress

611

Part 1

Mechanisms of Thermoregulation

612

 

Thermal Balance

612

 

Hypothalamic Temperature Regulation

613

 

Thermoregulation in Cold Stress: Heat Conservation and Heat Production

613

 

Thermoregulation in Heat Stress: Heat Loss

614

 

Effects of Clothing on Thermoregulation

618

Part 2

Thermoregulation and Environmental Heat Stress during Exercise

624

 

Exercise in the Heat

624

 

Maintaining Fluid Balance: Rehydration and Hyperhydration

627

 

Factors that Modify Heat Tolerance

630

 

Complications from Excessive Heat Stress

633

Part 3

Thermoregulation and Environmental Cold Stress during Exercise

635

 

Exercise in the Cold

635

 

Acclimatization to Cold

637

 

How Cold is Too Cold?

638

Chapter 26

Sport Diving

640

 

Diving History—Antiquity to the Present

641

 

Pressure-Volume Relationships and Diving Depth

645

 

Snorkeling and Breath-Hold Diving

646

 

Scuba Diving

650

 

Special Problems with Breathing Gases at High Pressures

653

 

Dives to Exceptional Depths: Mixed-Gas Diving

659

 

Energy Cost of Underwater Swimming

663

Chapter 27

Microgravity: The Last Frontier

665

 

The Weightless Environment

666

 

Historical Overview of Aerospace Physiology and Medicine

671

 

Modem Era

673

 

Medical Evaluation for Astronaut Selection

673

 

Physiologic Adaptations to Microgravity

676

 

Countermeasure Strategies

693

 

Overview of Physiologic Responses to Spaceflight

709

 

Vision for the Future of Space Exploration

710

 

Practical Benefits from Space Biology Research

714

Section 6

Body Composition, Energy Balance, and Weight Control   Dr. Claude Bouchard

721

Chapter 28

Body Composition Assessment

725

 

Overweight, Overfatness, and Obesity: No Unanimity for Terminology

728

 

The Body Mass Index: A Popular Clinical Standard

728

 

Composition of the Human Body

733

 

Common Techniques to Assess Body Composition

738

 

Average Percentage Body Fat

756

 

Determining Goal Body Weight

757

Chapter 29

Physique, Performance, and Physical Activity

759

 

Physiques of Champion Athletes

760

 

Upper Limit for Fat-Free Body Mass

778

Chapter 30

Overweight, Obesity, and Weight Control

780

Part 1

Obesity

781

 

Historical Perspective

781

 

Obesity Remains a Worldwide Epidemic

781

 

A Progressive Long-Term Process

784

 

Genetics Influences Body Fat Accumulation

787

 

Physical Inactivity: A Crucial Component in Excessive Fat Accumulation

789

 

Health Risks of Excessive Body Fat

790

 

Criteria for Excessive Body Fat: How Fat is Too Fat?

793

Part 2

Principles of Weight Control: Diet and Exercise

801

 

Energy Balance: Input versus Output

801

 

Dieting for Weight Control

802

 

Factors that Affect Weight Loss

810

 

Exercise for Weight Control

812

 

Effectiveness of Regular Physical Activity

814

 

Weight Loss Recommendations for Wrestlers and Other Power Athletes

822

 

Gaining Weight: The Competitive Athlete’s Dilemma

823

Section 7

Exercise Successful Aging, and Disease Prevention   Dr. Steven N. Blair

827

Chapter 31

Physical Activity, Health, and Aging

831

 

The Graying of America

832

Part 1

Physical Activity in the Population

835

 

Physical Activity Epidemiology

835

Part 2

Aging and Physiologic Function

842

 

Age Trends

842

 

Trainability and Age

852

Part 3

Physical Activity, Health, and Longevity

853

 

Causes of Death in the United States

854

 

Exercise, Health, and Longevity

854

 

Regular Moderate Exercise Provides Significant Benefits

856

 

Can Increasing Physical Activity Level Improve Health and Extend Life?

859

Part 4

Coronary Heart Disease

860

 

Changes on the Cellular Level

860

 

Coronary Heart Disease Risk Factors

864

Chapter 32

Clinical Exercise Physiology for Cancer, Cardiovascular, and Pulmonary Rehabilitation

876

 

The Exercise Physiologist in the Clinical Setting

877

 

Training and Certification Programs for Professional Exercise Physiologists

877

 

Clinical Applications of Exercise Physiology to Diverse Diseases and Disorders

879

 

Oncology

879

 

Cardiovascular Disease

885

 

Assessing Cardiac Disease

892

 

Stress Test Protocols

902

 

Prescribing Physical Activity and Exercise

904

 

Cardiac Rehabilitation

906

 

Pulmonary Diseases

909

 

Exercise and Asthma

917

 

Neuromuscular Diseases, Disabilities, and Disorders

919

 

Renal Disease

921

 

Cognitive/Emotional Diseases and Disorders

922

 

On the Horizon   Dr. Frank W. Booth

929

 

Molecular Biology—A New Vista for Exercise Physiology

933

 

Brief History Tour of Molecular Biology

936

 

Revolution in the Biologic Sciences

938

 

Human Genome

940

 

Nucleic Acids

942

 

How DNA Replicates

951

 

Protein Synthesis: Transcription and Translation

954

 

Mutations

971

 

New Horizons in Molecular Biology

979

 

Human Performance Research

1001

 

Index

1008