Table of Contents

 

 

 

 

Preface

vii

 

Acknowledgments

xiii

Chapter One

The Disease Process

1

 

Introduction

3

 

Predisposing Factors

3

 

Heredity

3

 

Age

3

 

Gender

3

 

Environment

3

 

Lifestyle

4

 

Hereditary Diseases

4

 

Classification of Hereditary Diseases

4

 

Chromosomal Disorders

7

 

Multifactorial Disorders

7

 

Inflammation and Infection

7

 

Fungi

8

 

Rickettsiae

9

 

Protozoa

9

 

Viruses

9

 

Bacteria

9

 

Parasites

10

 

Trauma

11

 

Head Trauma

11

 

Chest Trauma

12

 

Abdominopelvic Trauma

12

 

Neck and Spine Trauma

12

 

Extremities Trauma

12

 

Effects of Physical and Chemical Agents

12

 

Extreme Heat and Cold

12

 

Ionizing Radiation

13

 

Extremes of Atmospheric Pressure

13

 

Electric Shock

13

 

Poisoning

13

 

Near-Drowning

14

 

Bites of Insects, Spiders, and Snakes

14

 

Asphyxiation

14

 

Burns

14

 

Neoplasia and Cancer

15

 

Immune-Related Factors in Disease

15

 

The Immune Response

15

 

Nutritional Imbalance

18

 

Malnourishment

18

 

Vitamin Deficiencies and Excesses

18

 

Mineral Deficiencies and Excesses

18

 

Obesity

19

 

Starvation

19

 

Other Causes of Disease

20

 

Summary

20

 

Online Resources

20

 

Case Studies

20

 

Review Questions

23

Chapter Two

Integrative Medicine and Complementary Therapies

25

 

The Changing Climate for Complementary and Alternative Therapies

26

 

Definition of Terms

26

 

History of Conventional Medicine

27

 

History of Integrative Medicine

27

 

Integration of Both Worlds

27

 

Separating Fact from Fallacy

28

 

Alternative Systems of Medical Practice

28

 

Additional Therapies Referred to as Alternative

29

 

The Mind’s Connection with Health and Disease

30

 

Personal Responsibility

30

 

Influence of Lifestyle

30

 

Environmental Influences—Internal and External

31

 

Value of Good Nutrition

31

 

Stress and Distress

32

 

Managing Negative Emotions

32

 

Laughter and Play

33

 

Love, Friendship, and Faith

34

 

Summary

34

 

Online Resources

35

 

Case Studies

35

 

Review Questions

37

Chapter Three

Pain and its Management

41

 

Pain and its Treatment Models

42

 

Effective Pain Management

43

 

What is Pain?

43

 

Definition of Pain

43

 

the Experience of Pain

45

 

Gate Control Theory of Pain

45

 

Assessment of Pain

46

 

Treatment of Pain

47

 

Medications

47

 

Complementary Therapies

49

 

Physical Therapy

49

 

Biofeedback

50

 

Relaxation

50

 

Imagery

50

 

Hypnosis

50

 

Transcutaneous Electrical Nerve Stimulation

50

 

Massage

50

 

Humor, Laughter, and Play

50

 

Music

51

 

Acupuncture

51

 

Aromatherapy

51

 

Therapeutic Touch and Reiki

51

 

Yoga

52

 

Summary

52

 

Online Resources

52

 

Case Studies

53

 

Review Questions

55

Chapter four

Infectious and Communicable Diseases

57

 

Etiology of Infectious and Communicable Diseases

58

 

Emerging and Reemerging Infectious Diseases

60

 

Pandemics

60

 

H1N1 Flu (Swine Flu)

60

 

Escherichia Colt O157: H7

61

 

Lyme Disease

62

 

West Nile Virus

63

 

Malaria

64

 

Severe Acute Respiratory Syndrome (SARS)

65

 

Infectious Disease as Potential Weapons

66

 

Anthrax

67

 

Botulism

68

 

Plague (Pneumonic)

69

 

Smallpox (Variola)

70

 

Tularemia (Typhoidal or Pneumonic)

71

 

Viral Hemorrhagic Fevers

72

 

Viral Infections

73

 

Common Cold

73

 

Influenza

74

 

Multidrug-Resistant Organisms

75

 

Methicillin- Resistant Staphylococcus Aureus

75

 

Immunosuppressant Diseases

76

 

Chronic Fatigue Syndrome

76

 

HIV Infection/AIDS

77

 

Infectious and Communicable Diseases of Childhood and Adolescence

80

 

Infectious Diarrheal Diseases

80

 

Rubeola (Measles)

81

 

Rubella (German Measles)

82

 

Mumps

83

 

Varicella (Chickenpox)

83

 

Erythema Infectiosum (Fifth Disease)

84

 

Pertussis (Whooping Cough)

85

 

Diphtheria

86

 

Tetanus (Lockjaw)

87

 

Immunization

88

 

Summary

92

 

Online Resources

92

 

Case Studies

92

 

Review Questions

93

Chapter Five

Cancer

95

 

Description of Cancer

96

 

Definitions

96

 

Statistics

97

 

Etiology of Cancer

97

 

Carcinogens

98

 

Other Factors that Influence Cancer Development

98

 

Classification of Cancers

99

 

Carcinomas

99

 

Sarcomas

99

 

Cancers of the Blood and Lymph

99

 

Diagnostic Procedures for Cancer

100

 

Grading and Staging Cancer

100

 

Treatment of Cancer

101

 

Cancer Treatment

101

 

Preventing Cancer

105

 

Summary

105

 

Online Resources

106

 

Case Studies

106

 

Review Questions

107

Chapter Six

Congenital Diseases and Disorders

109

 

Description

111

 

Cardiovascular System Diseases and Disorders

111

 

Congenital Heart Defects

111

 

Sickle Cell Anemia

116

 

Nervous System Diseases and Disorders

117

 

Neural Tube Defects: Spina Bifida, Meningocele, and Myelomeningocele

117

 

Hydrocephalus

118

 

Cerebral Palsy

119

 

Digestive System Diseases and Disorders

120

 

Cleft Lip and Palate (Orofacial Clefts)

120

 

Tracheoesophageal Fistula and Esophageal Atresia

121

 

Pyloric Stenosis

122

 

Malrotation with Volvulus

123

 

Hirschsprung Disease (Congenital Aganghonic Megacolon)

123

 

Omphalocele

124

 

Genitourinary System Diseases and Disorders

125

 

Undescended Testes (Cryptorchidism)

125

 

Congenital Defects of the Ureter, Bladder, and Urethra

126

 

Musculoskeletal System Diseases and Disorders

127

 

Clubfoot (Talipes)

127

 

Congenital Hip Dysplasia

127

 

Duchenne Muscular Dystrophy

128

 

Metabolic Errors

129

 

Cystic Fibrosis

129

 

Phenylketonuria

130

 

Syndromes

131

 

Down Syndrome (Trisomy 21)

131

 

Fetal Alcohol Syndrome

132

 

Tourette Syndrome

133

 

Summary

134

 

Online Resources

134

 

Case Studies

135

 

Review Questions

137

Chapter Seven

Mental Health Diseases and Disorders

141

 

Integration of Health Care and Mental Health Care

142

 

Cost of Mental Health Care

143

 

Mental Health Insurance Coverage

143

 

Diagnostic Procedures

144

 

Mental Status Examination

144

 

Nature versus Nurture

145

 

Culture, Age, and Gender

145

 

Mood Disorders

145

 

Depression

145

 

Bipolar Disorder

149

 

Schizophrenia

150

 

Anxiety Disorders

152

 

Personality Disorders

154

 

Substance Abuse and Dependence

156

 

Disorders Generally Diagnosed during Childhood or Adolescence

159

 

Intellectual Disability

159

 

Autism Spectrum Disorders

161

 

Attention-Deficit-Hyperactivity Disorder (ADHD)

162

 

Eating Disorders

164

 

Anorexia Nervosa

164

 

Bulimia Nervosa

165

 

Sexual Disorders

166

 

Dyspareunia

166

 

Male Erectile Disorder

167

 

Female Sexual Arousal Disorder

168

 

Premature Ejaculation

169

 

Summary

169

 

Online Resources

170

 

Case Studies

170

 

Review Questions

173

Chapter Eight

Skin Diseases and Disorders

175

 

Integumentary System Anatomy and Physiology Review

176

 

Reconstructive Skin Procedures

178

 

Skin Lesions

178

 

Psoriasis

179

 

Urticaria (Hives)

181

 

Acne Vulgaris

182

 

Rosacea

184

 

Keratosis Pilaris

185

 

Alopecia Areata

185

 

Furuncles and Carbuncles

187

 

Pediculosis

188

 

Decubitus Ulcers

189

 

Corns and Calluses

191

 

Dermatophytoses

191

 

Scabies

193

 

Impetigo

194

 

Warts

194

 

Vituigo

195

 

Scleroderma

197

 

Dermatitis

198

 

Seborrheic Dermatitis

198

 

Contact Dermatitis

199

 

Latex Allergy

199

 

Atopic Dermatitis (Eczema)

200

 

Neurodermatitis

201

 

Herpes-Related Skin Lesions

202

 

Cold Sores and Fever Blisters

202

 

Herpes Zoster (Shingles)

204

 

Cancer

205

 

Skin Carcinomas

205

 

Malignant Melanoma

206

 

Common Symptoms of Skin Diseases and Disorders

207

 

Summary

207

 

Online Resources

207

 

Case Studies

208

 

Review Questions

209

Chapter Nine

Musculoskeletal Diseases and Disorders

211

 

Musculoskeletal System Anatomy and Physiology Review

212

 

Diseases and Disorders of Bones

215

 

Deformities of the Spine: Lordosis, Kyphosis, and Scoliosis

215

 

Herniated Intervertebral Disk

217

 

Osteoporosis

218

 

Osteomyelitis

220

 

Paget Disease (Osteitis Deformans)

221

 

Fractures

222

 

Dislocations

224

 

Joints

225

 

Osteoarthritis

225

 

Rheumatoid Arthritis

227

 

Gout

228

 

Muscles and Connective Tissue

229

 

Sprains and Strains

229

 

Bursitis and Tendonitis

230

 

Carpal Tunnel Syndrome

231

 

Plantar Fasciitis

232

 

Myasthenia Gravis

233

 

Polymyositis

234

 

Systemic Lupus Erythematosus

236

 

Fibromyalgia

237

 

Cancer

238

 

Common Symptoms of Musculoskeletal Diseases and Disorders

238

 

Summary

238

 

Online Resources

238

 

Case Studies

239

 

Review Questions

241

Chapter Ten

Nervous System Diseases and Disorders

243

 

Nervous System Anatomy and Physiology Review

245

 

Neurons

245

 

Central Nervous System

245

 

Peripheral Nervous System

247

 

Autonomic Nervous System

247

 

Meninges and Cerebrospinal Fluid

249

 

Headache

251

 

Acute and Chronic Headache

251

 

Migraine Headache

252

 

Head Trauma

253

 

Cerebral Concussion

253

 

Subdural Hematoma (Acute)

254

 

Traumatic Brain Injury

255

 

Cerebral Contusion

256

 

Abusive Head Trauma (Shaken Baby Syndrome)

257

 

Paralysis

258

 

Hemiplegia

258

 

Paraplegia and Quadriplegia

260

 

Infections of the Central Nervous System

261

 

Acute Bacterial Meningitis

261

 

Peripheral Nervous System Diseases and Disorders

262

 

Peripheral Neuropathy

262

 

Bell Palsy

263

 

Cerebral Diseases and Disorders

264

 

Cerebrovascular Accident (Stroke or Brain Attack)

264

 

Transient Ischemic Attacks

266

 

Cerebral Aneurysm

266

 

Epilepsy

267

 

Degenerative Neural Diseases and Disorders

268

 

Alzheimer Disease

268

 

Parkinson Disease

270

 

Multiple Sclerosis

272

 

Amyotrophic Lateral Sclerosis

273

 

Chronic Neurological Diseases and Disorders

273

 

Narcolepsy

273

 

Restless Leg Syndrome

274

 

Cancer

275

 

Tumors of the Brain

275

 

Common Symptoms of Nervous System Diseases and Disorders

276

 

Summary

276

 

Online Resources

276

 

Case Studies

277

 

Review Questions

279

Chapter Eleven

Endocrine System Diseases and Disorders

281

 

Endocrine System Anatomy and Physiology Review

283

 

Pituitary Gland Diseases and Disorders

283

 

Hyperpituitarism (Gigantism, Acromegaly)

286

 

Hypopituitarism

287

 

Diabetes Insipidus

288

 

Thyroid Gland Diseases and Disorders: Hyperthyroidism

289

 

Simple Goiter

290

 

Graves Disease

291

 

Thyroid Gland Diseases and Disorders: Hypothyroidism

292

 

Hashimoto Thyroiditis

292

 

Hypothyroidism (Cretinism, Myxedema)

293

 

Thyroid Cancer

294

 

Parathyroid Gland Diseases and Disorders

295

 

Hyperparathyroidism (Hypercalcemia)

295

 

Hypoparathyroidism (Hypocalcemia)

297

 

Adrenal Gland Diseases and Disorders

298

 

Cushing Syndrome

298

 

Addison Disease

299

 

Pancreas and the Islets of Langerhans Diseases and Disorders

300

 

Diabetes Mellitus

300

 

Gonadal Diseases and Disorders

303

 

Polycystic Ovary Syndrome (PCOS)

303

 

Common Symptoms of Endocrine System Diseases and Disorders

304

 

Summary

304

 

Online Resources

305

 

Case Studies

305

 

Review Questions

307

Chapter Twelve

Cardiovascular and Lymphatic Systems Diseases and Disorders

309

 

Cardiovascular and Lymphatic Systems Anatomy and Physiology Review

311

 

Heart

311

 

Blood and Blood Vessels

311

 

Lymph and Lymph Vessels

313

 

Carditis

316

 

Pericarditis

316

 

Myocarditis

317

 

Endocarditis

318

 

Valvular Heart Diseases and Disorders

320

 

Mitral Insufficiency/Stenosis

320

 

Aortic Insufficiency/Stenosis

321

 

Hypertensive Heart Disease

322

 

Essential Hypertension

322

 

Coronary Diseases and Disorders

323

 

Coronary Artery Disease

323

 

Angina Pectoris

325

 

Atrial Fibrillation

326

 

Myocardial Infarction (Heart Attack)

327

 

Congestive Heart Failure

329

 

Cardiac Arrest

330

 

Blood Vessel Diseases and Disorders

331

 

Aneurysms: Abdominal, Thoracic, and Peripheral Arteries

331

 

Arteriosclerosis/Atherosclerosis

332

 

Thrombophlebitis

334

 

Varicose Veins

335

 

Anemias

336

 

Iron-Deficiency Anemia

336

 

Folic Acid Deficiency Anemia

337

 

Pernicious Anemia

338

 

Aplastic Anemia

338

 

Leukemias

339

 

Acute Myeloid Leukemia

339

 

Acute Lymphoblastic Leukemia (ALL)

339

 

Chronic Myeloid Leukemia (CML)

339

 

Chronic Lymphocytic Leukemia (CLL)

339

 

Lymphatic Diseases and Disorders

342

 

Lymphedema

342

 

Lymphomas

343

 

Hodgkin Lymphoma

343

 

Non-Hodgkin Lymphoma (Lymphosarcoma)

344

 

Common Symptoms of Cardiovascular and Lymphatic Systems Diseases and Disorders

345

 

Summary

345

 

Online Resources

346

 

Case Studies

346

 

Review Questions

347

Chapter Thirteen

Respiratory System Diseases and Disorders

349

 

Respiratory System Anatomy and Physiology Review

351

 

Upper Respiratory Diseases and Disorders

354

 

Allergic Rhinitis

354

 

Sinusitis

355

 

Pharyngitis

356

 

Laryngitis

357

 

Epiglottitis

358

 

Infectious Mononucleosis

359

 

Lower Respiratory Diseases Id Disorders

360

 

Pneumonia

360

 

Legionella Pneumonia (Legionnaires Disease)

361

 

Chronic Obstructive Pulmonary Disease: Pulmonary Emphysema and Chronic Bronchitis

362

 

Bronchiectasis (Acquired)

365

 

Asthma

365

 

Lung Abscess

367

 

Pulmonary Tuberculosis

367

 

Pneumoconiosis

369

 

Silicosis

369

 

Asbestosis

370

 

Berylliosis

370

 

Anthracosis

371

 

Respiratory Mycoses

372

 

Pneumothorax (Collapsed Lung)

373

 

Atelectasis

374

 

Pleurisy (Pleuritis)

375

 

Pleural Effusion

376

 

Pulmonary Hypertension

376

 

Pulmonary Edema

377

 

Cor Pulmonale

378

 

Pulmonary Embolism

379

 

Respiratory Acidosis (Hypercapnia)

380

 

Respiratory Alkalosis (Hypocapnia)

381

 

Sleep Apnea

382

 

Lung Cancer

383

 

Childhood Respiratory Diseases Id Disorders

384

 

Sudden Infant Death Syndrome

384

 

Acute Tonsillitis

385

 

Adenoid Hyperplasia

386

 

Thrush

386

 

Croup

387

 

Common Symptoms of Respiratory Iseases and Disorders

388

 

Summary

388

 

Online Resources

388

 

Case Studies

389

 

Review Questions

391

Chapter Fourteen

Digestive System Diseases and Disorders

393

 

Digestive System Anatomy and Physiology Review

395

 

Upper Gastrointestinal Tract

399

 

Stomatitis (Herpetic and Aphthous)

399

 

Gastroesophageal Reflux Disease (Barrett Esophagus)

399

 

Gastritis

401

 

Peptic Ulcers

402

 

Gastroenteritis

404

 

Infantile Colic

404

 

Lower Gastrointestinal Tract

405

 

Celiac Disease (Gluten-Induced Enteropathy)

405

 

Irritable Bowel Syndrome

407

 

Diverticular Disease (Diverticulosis and Diverticulitis)

408

 

Acute Appendicitis

410

 

Hemorrhoids

411

 

Inflammatory Bowel Disease

412

 

Crohn Disease (Regional Enteritis, Granulomatous Colitis)

412

 

Ulcerative Colitis

413

 

Problematic Digestive System Symptoms

414

 

Constipation

415

 

Diarrhea

415

 

Hernias

416

 

Hiatal Hernia

416

 

Abdominal and Inguinal Hernias

418

 

Diseases of Accessory Organs of Digestion: Pancreas, Gallbladder, and Liver

419

 

Pancreatitis

419

 

Cholelithiasis and Cholecystitis

420

 

Cirrhosis

422

 

Viral Hepatitis (A, B, C, D, E)

423

 

Cancers of the Digestive System and Accessory Organs

425

 

Colorectal Cancer

425

 

Pancreatic Cancer

426

 

Common Symptoms of Digestive System Diseases and Disorders

427

 

Summary

427

 

Online Resources

427

 

Case Studies

428

 

Review Questions

429

Chapter Fifteen

Urinary System Diseases and Disorders

431

 

Urinary System Anatomy and Physiology Review

432

 

Infections of the Urinary System

434

 

Cystitis and Urethritis

434

 

Pyelonephritis (Acute)

437

 

Glomerulonephritis (Acute)

438

 

Kidney Diseases and Disorders

439

 

Renal Calculi (Uroliths or Kidney Stones)

439

 

Hydronephrosis

441

 

Acute Tubular Necrosis

441

 

Nephrotic Syndrome

442

 

Polycystic Kidney Disease

443

 

End-Stage Renal Disease

444

 

Other Urinary Diseases and Disorders

446

 

Neurogenic or Overactive Bladder

446

 

Cancers of the Urinary System

447

 

Bladder Cancer

447

 

Renal Cell Carcinoma or Kidney Cancer

448

 

Common Symptoms of Urinary System Diseases and Disorders

449

 

Summary

449

 

Online Resources

450

 

Case Studies

450

 

Review Questions

451

Chapter Sixteen

Reproductive System Diseases and Disorders

453

 

Reproductive System Anatomy and Physiology Review

455

 

Male Reproductive System

455

 

Female Reproductive System

456

 

Sexual Health

458

 

Infertility

459

 

Male Infertility

459

 

Female Infertility

459

 

Sexually Transmitted Diseases

460

 

Gonorrhea

460

 

Genital Herpes

461

 

Genital Human Papillomavirus (HPV) Infection

462

 

Syphilis

463

 

Trichomoniasis

465

 

Chlamydial Infections

466

 

Common Symptoms of Sexually Transmitted Diseases (STDs)

466

 

Male Reproductive Diseases and Disorders

467

 

Benign Pro Static Hyperplasia

467

 

Prostatitis

468

 

Epididymitis

469

 

Prostatic Cancer

470

 

Testicular Cancer

471

 

Common Symptoms of Male Reproductive Diseases and Disorders

471

 

Female Reproductive Diseases and Disorders

471

 

Premenstrual Syndrome

471

 

Amenorrhea

473

 

Dysmenorrhea

474

 

Ovarian Cysts and Tumors

475

 

Endometriosis

476

 

Uterine Leiomyomas

477

 

Pelvic Inflammatory Disease

478

 

Menopause

479

 

Ovarian Cancer

480

 

Diseases and Disorders of the Breasts

482

 

Fibrocystic Breasts

482

 

Benign Fibroadenoma

483

 

Carcinoma of the Breast

483

 

Common Symptoms of Female Reproductive System Diseases and Disorders

486

 

Diseases and Disorders of Pregnancy and Delivery

486

 

Spontaneous Abortion

487

 

Ectopic Pregnancy

487

 

Pregnancy-Induced Hypertension (Preeclampsia and Eclampsia)

488

 

Placenta Previa

489

 

Abruptio Placentae

490

 

Premature Labor/Premature Rupture of Membranes

490

 

Common Symptoms of Diseases and Disorders of Pregnancy and Delivery

491

 

Summary

492

 

Online Resources

492

 

Case Studies

493

 

Review Questions

495

Chapter Seventeen

Eye and Ear Diseases and Disorders

497

 

Eye and Ear Anatomy and Physiology Review

498

 

Eyes

498

 

Ears

499

 

Eye Diseases and Disorders

501

 

Refractive Errors

501

 

Nystagmus

503

 

Stye (Hordeolum)

503

 

Corneal Abrasion

504

 

Cataract

505

 

Glaucoma

506

 

Retinal Detachment

507

 

Age-Related Macular Degeneration

508

 

Strabismus

510

 

Eye Inflammations

511

 

Conjunctivitis

511

 

Uveitis

512

 

Blepharitis

513

 

Keratitis

513

 

Common Symptoms of Eye Diseases and Disorders

514

 

Ear Diseases and Disorders

514

 

Impacted Cerumen

514

 

External Otitis (Swimmer’s Ear)

515

 

Otitis Media

515

 

Otosclerosis

517

 

Motion Sickness

517

 

Meniere Disease

518

 

Hearing Loss and Deafness

519

 

Common Symptoms of Ear Diseases and Disorders

520

 

Summary

520

 

Online Resources

521

 

Case Studies

521

 

Review Questions

523

 

Glossary

525

Appendix 1

Diagnostic Procedures

539

Appendix 2

References

551

Appendix 3

Abbreviations

559

 

Subject Index

565

 

Index of Diseases and Disorders

585