Table
of Contents
|
|
|
|
Preface |
7 |
|
Abbreviations |
8 |
|
GENERAL PATHOLOGY |
|
|
Introduction |
|
1 |
The Normal
Human Cell |
12 |
2 |
Fluid
Dynamics |
14 |
|
Tissue Damage |
|
3 |
Tissue
Types and the Effects of Tissue Damage |
16 |
4 |
Cell Death |
18 |
5 |
Harmful
Agents in the Environment |
20 |
6 |
The Effects
of Tobacco Alcohol and Other Drugs |
22 |
7 |
Nutritional
Disorders |
24 |
|
Inflammation and Immunity |
|
8 |
The Body’s
Natural Defences |
26 |
9 |
B Cells and
Immunoglobulins |
28 |
10 |
T Cells |
30 |
11 |
The Major
Histocompatibility Complex |
32 |
12 |
The
Reticuloendothelial System |
34 |
13 |
Acute
Inflammation |
36 |
14 |
Chronic
Inflammation |
38 |
15 |
Wound
Healing and Repair |
40 |
16 |
Infection
and Immunodeficiency |
42 |
17 |
Shock |
44 |
18 |
Tolerance
and Autoimmune Disease |
46 |
19 |
Hypersensitivity
Reactions |
48 |
20 |
Overview of
Inflammation and Immunity |
50 |
|
Genetics |
|
21 |
Cell Division |
52 |
22 |
Genetic
Disease |
54 |
|
Neoplasia |
|
23 |
Disordered
Cell Growth |
56 |
24 |
Basic
Concepts in Neoplasia |
58 |
25 |
Tumorigenesis
and Oncogenesis |
60 |
26 |
Oncogenes
and Tumour Suppressor Genes |
62 |
27 |
Common
Carcinoma Histological Subtypes |
64 |
28 |
Tumour
Prognosis and Treatment |
66 |
|
SYSTEMS PATHOLOGY |
|
|
Multisystems Disease |
|
29 |
Sarcoidosis
and Syphilis |
70 |
30 |
Wilson’s
Disease and Haemochromatosis |
72 |
31 |
Systemic Vasculitis |
74 |
|
Cardiovascular Disease |
|
32 |
Normal
Blood Vessels and Types of Aneurysm |
76 |
33 |
Congenital
Heart Disease |
78 |
34 |
Systemic
Hypertension |
80 |
35 |
Atherosclerosis |
82 |
36 |
Ischaemic
Heart Disease |
85 |
37 |
Thrombosis |
88 |
38 |
Embolism
and Disseminated Intravascular Coagulation |
91 |
39 |
Cardiac
Valvular Disease |
94 |
40 |
Myocardial
and Pericardial Disease |
96 |
|
Respiratory Disease |
|
41 |
Pulmonary
Vascular Disorders |
98 |
42 |
Pneumonia |
100 |
43 |
Bronchiectasis |
102 |
44 |
Tuberculosis |
104 |
45 |
Chronic
Obstructive Pulmonary Disease |
106 |
46 |
Fibrosing
Alveolitis |
108 |
47 |
Primary
Lung Carcinoma |
110 |
48 |
Other
Tumours of the Lung and Pleura |
112 |
|
Gastrointestinal Tract Disease |
|
49 |
Malabsorption |
114 |
50 |
Peptic
Ulceration and Helicobacter Pylori |
116 |
51 |
Oesophageal
Disease |
|
52 |
Tumours of
the Stomach and Small Intestine |
120 |
53 |
Mechanical
Disease of the Gastrointestinal Tract |
122 |
54 |
Ulcerative
Colitis and Crohn’s Disease |
124 |
55 |
Adenomatous
Polyps Colorectal Cancer and Anal Carcinoma |
126 |
|
Hepatic and Pancreaticobiliary Disease |
|
56 |
Normal
Liver and the Effects of Liver Damage |
128 |
57 |
Jaundice
Gallstones and Carcinoma of the Gallbladder |
130 |
58 |
Alcoholic
and Non-Alcoholic Liver Disease |
132 |
59 |
Autoimmune
Hepatitis and Cholangiopathies |
134 |
60 |
Viral
Hepatitis |
136 |
61 |
Cirrhosis |
139 |
62 |
Acute and
Chronic Pancreatitis |
142 |
63 |
Tumours of
the Liver Biliary Tree and Pancreas |
144 |
|
Genitourinary Tract Disease |
|
64 |
Congenital
and Inherited Abnormalities of the Kidney and Urinary Tract |
146 |
65 |
The Nephron
and Renal Aspects of Hypertension |
148 |
66 |
Glomerulonephritis |
150 |
67 |
Important
Types of Glomerulonephritis |
152 |
68 |
Tubulointerstitial
Diseases |
154 |
69 |
Renal
Neoplasms |
156 |
70 |
Bladder
Tumours |
158 |
71 |
Testicular
Cancer |
160 |
72 |
Prostatic
Disease |
162 |
|
Gynaecological and Obstetric Disease |
|
73 |
Ovarian
Tumours |
164 |
74 |
Benign
Uterine Conditions |
166 |
75 |
Uterine
Cancer |
168 |
76 |
Cervical
Cancer |
170 |
77 |
Obstetric
Pathology |
172 |
78 |
Paediatric
Tumours |
174 |
|
Nervous System Disease |
|
79 |
Cerebrovascular
Accidents |
176 |
80 |
Cerebrovascular
Accident Syndromes |
178 |
81 |
Raised
Intracranial Pressure |
179 |
82 |
Traumatic
Injury and Intracranial Haemorrhage |
180 |
83 |
Central
Nervous System Tumours |
182 |
84 |
Infections
of the Nervous System |
184 |
85 |
Movement
Disorders |
186 |
86 |
Acquired
Disorders of Myelination |
188 |
87 |
Dementia |
190 |
|
Endocrine Disease |
|
88 |
Pituitary
Pathology |
192 |
89 |
Non-Neoplastic
Pathology of the Thyroid |
194 |
90 |
Thyroid
Neoplasms |
196 |
91 |
Parathyroid
Gland Pathology |
198 |
92 |
Adrenal
Pathology |
200 |
93 |
Diabetes
Mellitus |
202 |
|
Head and Neck Pathology |
|
94 |
Head and
Neck Pathology |
204 |
|
Lymphoreticular Disease |
|
95 |
Lymphoma |
206 |
96 |
Myeloma |
208 |
97 |
Assorted
Haematological Conditions |
210 |
|
Musculoskeletal
Disease |
|
98 |
Muscle
Disorders |
212 |
99 |
Arthritis |
214 |
100 |
Miscellaneous
Non-Neoplastic Osteoarticular Pathology |
216 |
101 |
Bone Tumours |
218 |
|
Skin Disease |
|
102 |
Inflammatory
Dermatoses |
220 |
103 |
Benign Skin
Tumours |
222 |
104 |
Malignant
Skin Tumours |
224 |
|
Breast Disease |
|
105 |
Benign
Breast Disease |
226 |
106 |
Breast
Carcinoma |
228 |
|
Self-Assessment |
|
|
Case
Studies and Questions |
|
|
Answers |
|
|
Glossary |
|
|
Reference
Ranges |
242 |
|
Index |
243 |
|
|