Contributors

vii

Preface

ix

PART I

PREDIABETES AND THE FHAGNOSIS OF DIABETES

1

IS Prediabetes a Risk Factor or is it a Disease?   Kalpana Muthusamy and Adrian Vella

3

2

Early Diagnosis of Type 1 Diabetes: Useful or a Phyrrhic Victory?   Chiara Guglielmiand Paolo Pozzilli

11

3

How should Secondary Causes of Diabetes be Excluded?   Aonghus O’Loughlin and Sean F. Dinneen

22

4

Screening Patients with Prediabetes and Diabetes for Cardiovascular Disease   Deepika S. Reddy and Vivian Fonseca

34

PART II

INITIAL EVALUATION AND MANAGEMENT OF DIABETES

5

What is the Role of Self-Monitoring in Diabetes? is there a I Role for Postprandial Glucose Monitoring? How does Continuous Glucose Monitoring Integrate into Clinical Practice?   Rami Almokayyad and Ruben Cuddihy

43

6

The Optimal Diet for Diabetes Is?   Maria L. Collazo-Clavell

56

7

How to Determine When to Pursue Lifestyle Change Alone versus Pharmacotherapy at Diagnosis?   Galina Smushkin and E John Service

64

8

Insulin Sensitizers versus Secretagogues as First-Line Therapy for Diabetes: Rationale for Clinical Choice   Robert J. Richards, L Yvonne Melendez-Ramirez, and William T. Cefalu

71

9

Are Insulin Sensilizers Useful Additions to Insulin Therapy?   John W. Richard III and Philip Raskin

79

10

Is there a Role for Incierin-Based Therapy in Combination with Insulin?   Matheni Sathananthan and Adrian Vella

91

11

Hba1c: is it the Most Important Therapeutic Target in Outpatient Management of Diabetes?   Steven A. Smith

96

PART III

MANAGEMENT OF ASSOCIATED RISK FACTORS AND DISEASE

12

Primary Therapy for Obesity as the Treatment of Type 2 Diabetes   Manpreet S. Mundi and Michael D. Jensen

107

13

Are Statins the Optimal Therapy for Cardiovascular Risk in Patients with Diabetes? Are Triglycerides an Important Independent Risk Factor for Diabetes?   Michael O’Reilly and Timothy O’Brien

116

14

The Role of Bariatric Surgery in Obese Patients with Diabetes: Primary or Rescue Therapy?   Praveena Gandikota and Blandine Laferrère

127

15

Hyperglycemia should be Avoided in Critical Illness and the Postoperative Period   Kalpana Muthusamy and John M. Miles

134

16

Is there an Optimal Revascularization Strategy in Diabetic Patients with Ischemic Heart Disease?   Stephen H. McKellar, Morgan L. Brown, and Robert L. Frye

145

Index

153