Table of Contents

 

 

 

 

Preface

xi

 

Dedication

xii

 

Abbreviations

xiii

PART 1

GENERAL DERMATOLOGY

 

 

Work-up Quick Reference

3

 

Direct Immunofluorescence - Where to Biopsy?

3

 

False Positive/Negative Difs

4

 

Biopsy for GVHD

4

 

The Dermatologic Differential Algorithm

4

 

Alopecia Work-Up

5

 

Associations

5

 

Cicatricial or Non-Cicatricial?

5

 

Aphthosis Classification and Workup

9

 

Morphologic Classification

9

 

Classification By Cause

9

 

Work-Up for Complex Apthae

9

 

Treatment

9

 

Amyloidoses

10

 

Xanthomas

11

 

Hyperlipoproteinemias: Fredrickson Classification

12

 

Histiocytosis

13

 

Lupus Erythematosus

17

 

Systemic Lupus Erythematosus Criteria (4 of 11)

17

 

Acute Cutaneous Lupus Erythematosus

17

 

Subacute Cutaneous Lupus Erythematosus

17

 

Chronic Cutaneous Lupus Erythematosus

17

 

Autoantibody Sensitivities and Specificities

18

 

Antinuclear Antibodies

20

 

Autoantibodies in Connective Tissue Diseases

21

 

Vasculitis

22

 

Treatment of ANCA-Associated Vasculitis

22

 

Anti-Neutrophil Cytoplasmic Antibody

23

 

Small Vessel Vasculitis

24

 

Medium (± Small) Vessel Vasculitis

26

 

Large Vessel Vasculitis

27

 

Cryoglobulinemia

28

 

CTCL Classification

29

 

Mycosis Fungoides Variants

29

 

MF (TNMB) Staging

31

 

MF Treatment Algorithm

32

 

Cutaneous B-Cell Lymphoma

33

 

Leukemia Cutis

33

 

Monoclonal Gammopathies

34

 

Melanoma – Classification

35

 

Breslow Depth

36

 

Melanoma – Staging and Survival

36

 

Melanoma – Treatment Guidelines

37

 

Infectious Disease

39

 

Viruses and Diseases

39

 

Human Papiliomavirus

41

 

Other Viral Diseases

42

 

Mycoses

45

 

Vector-Borne Diseases

52

 

Creatures in Dermatology

58

 

Immunology

63

 

Complement

63

 

Complement Deficiencies

64

 

Angioedema and Complement Levels

64

 

Th Profiles

65

 

Bullous Disorders

65

 

Intracorneal/Subcorneal

65

 

Intraepidermal Blisters

66

 

Suprabasilar Blisters

66

 

Subepidermal with Little Inflammation

66

 

Subepidermal with Lymphocytes

67

 

Subepidermal with Eosinophils

67

 

Subepidermal with Neutrophils

67

 

Subepidermal with Mast Cells

68

 

Epidermolysis Bullosa

68

 

Major Bullous Diseases - Clinicopathologic Findings

71

 

Glands

75

 

Disorders or Drugs Associated with Skeletal, Ocular, and/or Nail Findings

77

 

Dermatoses of Pregnancy

88

 

Neonatal Vesiculopustular Eruptions

90

 

Genital Ulcers

95

 

Common Contact Allergens

96

 

Features Suggestive of Specific Irritant/Toxin

100

 

Plants and Dermatoses

100

 

Vitamin Deficiencies/Hypervitaminoses

103

 

Genodermatoses

107

 

Gene List

107

 

Chromosome Abnormalities

133

 

Tumors

134

 

Disorders of Cornification

136

 

Disorders of Hair, Nail, Ectoderm

139

 

Tumor Syndromes

144

 

Disorders of Connective Tissue

146

 

Disorders of Metabolism

149

 

Disorders of Pigmentation

154

 

Disorders of Vascularization

156

 

Immunodeficiency Syndromes

159

 

Miscellaneous

162

 

Dermoscopy

163

 

Pathology

165

 

Histochemical Staining

165

 

Immunohistochemical Staining

167

 

Pathologic Bodies

170

 

Other Derm Path Buzzwords, Patterns, DDx

175

PART 2

SURGERY

 

 

Surgical Margins Guidelines

183

 

Indications for Mohs Micrographic Surgery

183

 

Guideline for Prophylactic Antibiotics

184

 

Algorithm for Antibiotic Prophylaxis

185

 

Guideline for Prophylactic Antivirals

186

 

Anesthetics

186

 

Dose Calculation

186

 

Tumescent Anesthesia

186

 

Topical Anesthetic

187

 

Adverse Reaction to Local Anesthetics

187

 

Local Anesthetic

188

 

Nerve Blocks

189

 

Surgical Anatomy

189

 

Anatomy of the Face

189

 

Anatomy of the Nail

193

 

Danger Zones in Surgery

194

 

Dermatomal Distribution of Sensory Nerves

196

 

Anatomy of the Lower Extremity Venous System

197

 

Cutaneous Reconstruction

198

 

Undermining Depths in Reconstruction

199

 

Dangerzone of the Neck: Erbs Point

196

 

Second Intention

199

 

Simple Linear Closure

200

 

Transposition Flap

201

 

Advancement Flap

204

 

Interpolation Flap

206

 

Rotation Flap

207

 

Skin Graft

208

 

Sutures

210

 

Absorbable

210

 

Non-Absorbable

211

 

Suture Removal Time

212

 

Electrosurgery

212

 

Wound Healing

212

 

Wound Dressing

213

 

Antiseptic Scrubs

214

 

Lasers

216

 

Laser Principles

217

 

Thermal Relaxation Time

217

 

Laser Treatment of Tattoo Pigment

218

 

Photoinduced Eye Injury

218

 

Photodynamic Therapy

220

 

Basic Principles

220

 

Applications

220

 

Photosensitizer Properties and Options

220

 

UV Spectrum

222

 

UV Protection Measurements

223

 

UV Associations/Specificities

223

 

Glogau Wrinkle Scale

224

 

Fitzpatrick Skin Type

224

 

Peeling Agents

224

 

TCA Peel

225

 

TCA Peel Frost Level

225

 

Jessner Solution

225

 

Baker-Gordon Phenol

226

 

Cook Total Body Peel

226

 

Pre-Peel Prep

226

 

Post-Peel Wound Care

226

 

Botulinum Toxin

226

 

Botox Injection Sites

227

 

Fillers

229

 

Sclerotherapy

234

 

Determine Vessel Size Using Needle Gauge

236

 

Recommended Maximum Effective Concentration of Sclerosant to Minimize Side Effects

236

PART 3

DRUGS AND THERAPIES

 

 

Medication Quick Reference

239

 

Topical Steroids

239

 

Non-Steroidals

240

 

Commonly Used Drugs in Dermatology

240

 

Systemic Medications

243

 

Antimalarials

243

 

Immunosuppressive Agents

244

 

Systemic Retinoids

246

 

Biologics

247

 

General Reference

249

 

Metric Measurements

249

 

Dosage Calculation

249

 

Drug Dispensing and Absorption

249

 

Corticosteroid

249

 

Acne – Topical

250

 

Antibiotics

250

 

Keratolytics

250

 

Acne – Systemic

251

 

Antibiotics

251

 

Retinoids

252

 

Others

252

 

Alopecia

252

 

Analgesics

252

 

Anesthetics–Topical

253

 

Antibiotics

253

 

Topical/Antiseptic

253

 

Systemic

254

 

Antibiotic Preoperative Prophylaxis, See p. 184

 

 

Antibiotic Regimens

255

 

STDs

257

 

Antifungals

257

 

Topical

257

 

Systemic

258

 

Antifungal Regimens

260

 

Antiparasitics

261

 

Antivirals

262

 

For HSV Labialis – Topical Agents

262

 

For HSV 1 or 2 – Oral Agents

262

 

For HSV Disseminated Disease

262

 

For Herpes Zoster/VZV

262

 

For Genital Warts

263

 

For Verruca Vulgaris

263

 

For Molluscum

263

 

Antihistamines

263

 

Sedating

263

 

Non-Sedating

264

 

H2-Blockers

264

 

Antipruritic

264

 

Topical

264

 

Oral

264

 

Bleaching Agents/Depigmenting Agents

265

 

Topical Chemotherapy

266

 

Actinic Keratoses (AK)

266

 

Basal Cell Carcinoma (BCC) - Superficial BCC

266

 

CTCL

266

 

Topical Agents

266

 

Oral Agent

266

 

Other Agent

267

 

Psoriasis

267

 

Topical Agents

267

 

Tar

267

 

Systemic Agents

267

 

Seborrheic Dermatitis

268

 

Hypertrichosis

268

 

Hyperhidrosis

268

 

Wound Care

269

 

Vitamins/Nutritional Supplements

269

 

Miscellaneous Meds

269

 

Cytochrome P-450 Interactions

270

 

Pregnancy Categories of Commonly Used Dermatologic Agents

272

 

Common Dermatologic Drugs and Teratogenic Effects

273

 

Dermatologic Drugs Reportedly Associated with Contraceptive Failure

273

 

Drug Eruptions

274

 

Chemotherapeutic Agents and Skin Changes

277

 

Antidote to Extravasation of Chemotherapeutic Agents

279

 

UV Light Treatment

279

 

UVA/UVB Dosing

279

 

NBUVB Dosing

280

 

PUVA

280

 

Washington University Dermatology Toxic Epidermal Necrolysis (TEN) Protocol

282

 

Diagnosis of TEN

282

 

Triage Algorithm for TEN Patients

283

 

Treatment for All TEN Patients

283

 

Index

287