Table
of Contents
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PART I |
OVERVIEW |
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Chapter 1 |
Neonatal
and Perinatal
Epidemiology Nigel Paneth |
1 |
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Chapter 2 |
Evaluation
of Therapeutic Recommendations, Database Management, and Information
Retrieval Peter Tarczy-Hornoch |
10 |
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Chapter 3 |
Ethics,
Data, and Policy in Newborn Intensive Care William L. Meadow and John D. Lantos |
18 |
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Chapter 4 |
Global Neonatal Health Linda L. Wright |
23 |
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P ART II |
FETAL DEVELOPMENT |
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Chapter 5 |
Immunologic
Basis of Placental Function and Diseases: the Placenta, Fetal Membranes, and
Umbilical Cord Satyan Kalkunte, James F. Padbury
and Surendra
Sharma |
37 |
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Chapter 6 |
Abnormalities
of Fetal Growth Rebecca
Simmons |
51 |
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Chapter 7 |
Multiple Gestations and Assisted Reproductive Technology Kerri Marquard and Kelle Moley |
60 |
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Chapter 8 |
Nonimmune Hydrops Scott A. Lorch and
Thomas J. Mollen |
67 |
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PART III |
MATERNAL HEALTH AFFECTING NEONATAL OUTCOME |
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Chapter 9 |
Endocrine
Disorders in Pregnancy Gladys
A. Ramos and Thomas R. Moore |
75 |
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Chapter 10 |
Maternal Medical Disorders of Fetal Significance: Seizure Disorders, Isoimmun1zation, Cancer, and Mental Health Disorders Thomas F. Kelly and Thomas R. Moore |
92 |
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Chapter 11 |
Hypertensive
Complications of Pregnancy Andrew D. Hull and Thomas R. Moore |
105 |
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Chapter 12 |
Perinatal Substance Abuse Linda D. Wallen and Christine A. Gleason |
111 |
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PART IV |
LABOR AND DELIVERY |
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Chapter 13 |
Antepartum Fetal Assessment Christian M. Pettker and Katherine H. Campbell |
129 |
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Chapter 14 |
Prematurity: Causes and Prevention Tonse N.K. Raju and Caroline Signore |
140 |
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Chapter 15 |
Complicated Deliveries: Overview Sarah A. Waller, Sameer Gopalani and Thomas J. Benedetti |
146 |
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Chapter 16 |
Obstetric Analgesia and Anesthesia Mark D. Rollins and Mark A. Rosen |
159 |
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PART V |
GENETICS |
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Chapter 17 |
Impact of
the Human Genome Project on Neonatal Care Jeffrey C. Murray |
173 |
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Chapter 18 |
Prenatal Genetic Diagnosis Diana W. Bianchi |
180 |
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Chapter 19 |
Evaluation
of the Dysmorphic
Infant |
186 |
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Chapter 20 |
Specific
Chromosome Disorders in Newborns |
196 |
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PART VI |
METABOLIC AND ENDOCRINE DISORDERS OF THE NEWBORN |
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Chapter 21 |
Introduction
to Metabolic and Biochemical Genetic Disease Stephen Cederbaum |
209 |
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Chapter 22 |
Inborn
Errors of Carbohydrate, Ammonia, Amino Acid, and Organic Acid
Metabolism Stephen Cederbaum
and Gerard T. Berry |
215 |
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Chapter 23 |
Lysosomal Storage, Peroxisomal, and Glycosylation Disorders and Sm1th-Lemli-Opitz Syndrome in the Neonate Janet A. Thomas, Carol L. Greene and Gerard T. Berry |
239 |
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Chapter 24 |
Skeletal Dysplasias and Connective Tissue Disorders David L. Rimoin and George E. Tiller |
258 |
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PART VII |
CARE OF THE HEALTHY NEWBORN |
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Chapter 25 |
Initial Evaluation: History and Physical Examination of the Newborn Jeffrey B. Smith |
277 |
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Chapter 26 |
Routine Newborn Care James A. Taylor, Jeffrey A. Wright and David Woodrum |
300 |
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Chapter 27 |
Newborn Screening Inderneel Sahai and Harvey L. Levy |
316 |
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Chapter 28 |
Resuscitation in the Delivery Room Tina A. Leone and Neil N. Finer |
328 |
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PART VIII |
CARE OF THE HIGH-RISK INFANT |
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Chapter 29 |
Stabilization and Transport of the High-Risk Infant George A. Woodward, Roxanne Kirsch, Michael Stone Trautman, Monica E. Kleinman, Gil Wernovsky and Bradley S. Marino |
341 |
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Chapter 30 |
Temperature Regulation of the Premature Neonate Stephen Baumgart and Sudhish Chandra |
357 |
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Chapter 31 |
Acid-Base, Fluid, and Electrolyte Management Michael A. Posencheg and Jacquelyn R. Evans |
367 |
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Chapter 32 |
Care of the
Extremely Low-Birthweight Infant Eric C. Eichenwald |
390 |
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Chapter 33 |
Care of the Late Preterm Infant Sowmya S. Mohan and Lucky Jain |
405 |
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Chapter 34 |
Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics Robert M. Ward, Steven E. Kern and Ralph A. Lugo |
417 |
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Chapter 35 |
Neonatal Pain and Stress: Assessment and Management Dennis E. Mayock and Christine A. Gleason |
429 |
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PART IX |
IMMUNOLOGY AND INFECTIONS |
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Chapter 36 |
Immunology of the Fetus and Newborn Calvin B. Williams, Eli M. Eisenstein and F. Sessions Cole |
445 |
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Chapter 37 |
Viral Infections of the Fetus and Newborn and Human Immunodeficiency Virus Infection during Pregnancy Mark R. Schleiss and Janna C. Patterson |
468 |
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Chapter 38 |
Toxoplasmosis, Syphilis, Malaria, and Tuberculosis Pablo J. Sánchez, Janna C. Patterson and Amina Ahmed |
513 |
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Chapter 39 |
Neonatal Bacterial Sepsis Patricia Ferrieri and Linda D. Waller |
538 |
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Chapter 40 |
Health
Care-Acquired Infections in the Nursery David A. Munson and Jacquelyn R. Evans |
551 |
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Chapter 41 |
Fungal
Infections in the Neonatal Intensive Care Unit Margaret K. Hostetter |
565 |
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PART X |
RESPIRATORY SYSTEM |
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Chapter 42 |
Lung Development: Embryology, Growth, Maturation, and Developmental Biology Maria Victoria Fraga and Susan Guttentag |
571 |
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Chapter 43 |
Control of Breathing Estelle B. Gauda and Richard J. Martin |
584 |
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Chapter 44 |
Pulmonary Physiology of the Newborn Robert M. DiBlasi, C. Peter Richardson and Thomas Hansen |
593 |
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Chapter 45 |
Principles of Respiratory Monitoring and Therapy Eduardo Bancalari and Nelson Claure |
612 |
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Chapter 46 |
Respiratory
Distress in the Preterm Infant J. Craig Jackson |
633 |
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Chapter 47 |
Respiratory Failure in the Term Newborn Thomas A. Parker and John P. Kinsella |
647 |
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Chapter 48 |
Bronchopulmonary Dysplasia Roberta L. Keller and Roberta A. Ballard |
658 |
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Chapter 49 |
Surgical Disorders
of the Chest and Airways Roberta
L. Keller, |
672 |
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PART XI |
CARDIOVASCULAR SYSTEM |
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Chapter 50 |
Embryology and Physiology of the Cardiovascular System H. Scott Baldwin and Ellen Dees |
699 |
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Chapter 51 |
Cardiovascular Compromise in the Newborn Infant Istvan Seri and Barry Markovitz |
714 |
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Chapter 52 |
Persistent Pulmonary Hypertension Robin H. Steinhorn and Steven H. Abman |
732 |
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Chapter 53 |
Fetal and Neonatal Echocardiography Margaret M. Vernon and Mark Lewin |
741 |
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Chapter 54 |
Patent Ductus
Arteriosus
in the Preterm Infant Ronald
I. Clyman |
751 |
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Chapter 55 |
Congenital Heart Disease Thomas D. Scholz and Benjamin E. Beinking |
762 |
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Chapter 56 |
Arrhythmias in the Newborn and Fetus Jeremy P. Moore, Gary M. Satou and Thomas S. Klitzner |
789 |
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Chapter 57 |
Neurodevelopmental Outcomes in Children with Congenital Heart Disease Gil Wernovsky |
801 |
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PART XII |
NEUROLOGIC SYSTEM |
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Chapter 58 |
Developmental Physiology of the Central Nervous System Christine A. Gleason, A. Roger Hotiimer and Stephen A. Back |
811 |
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Chapter 59 |
Neonatal Neuroimaging Sanjay P. Prabhu, P. Ellen Grant, Richard L. Robertson and George A. Taylor |
816 |
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Chapter 60 |
Congenital Malformations of the Central Nervous System Stephen A. Back and Lauren L. Plawner |
844 |
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Chapter 61 |
Central Nervous System Injury and Neuroprotection Sonia L. Bonifacio, Fernando Gonzalez and Donna M. Ferriero |
869 |
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Chapter 62 |
Neonatal Neuromuscular Disorders Eugenio Mercuri and Marika Pane |
892 |
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Chapter 63 |
Neonatal
Seizures Mark S. Scher |
901 |
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Chapter 64 |
Risk Assessment and Neurodevelopmental Outcomes Mary Leppert and Marilee C. Allen |
920 |
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PART XIII |
NUTRITION |
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Chapter 65 |
Breastfeeding |
937 |
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Chapter 66 |
Enteral Nutrition for the Hlgh-Risk Neonate Brenda B. Poindexter and Richard J. Schanler |
952 |
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Chapter 67 |
Parenteral Nutrition Brenda B. Poindexter and Scott C. Denne |
963 |
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PART XIV |
GASTROINTESTINAL SYSTEM |
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Chapter 68 |
Developmental Anatomy and Physiology of the Gastrointestinal Tract Reed A. Dimmitt and Eric Sibley |
973 |
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Chapter 69 |
Structural Anomalies of the Gastrointestinal Tract Clara Song, Jeffrey S. Upperman and Victoria Niklas |
979 |
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Chapter 70 |
Innate and Mucosal Immunity in the Developing Gastrointestinal Tract: Relationship to Early and Later Disease Camilia R. Martin and W. Allan Walker |
994 |
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Chapter 71 |
Abdominal
Wall Problems Dan Poenaru |
1007 |
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Chapter 72 |
The Developing Intestinal Microbiome: Implications for the Neonate Josef Neu, Christopher M. Young and Volker Mai |
1016 |
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Chapter 73 |
Necrotizing Enterocolitis
and Short Bowel Syndrome Michael
Caplan |
1022 |
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Chapter 74 |
Disorders of the Liver Frederick J. Suchy and Nanda Kerkar |
1030 |
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PART XV |
HEMATOLOGIC SYSTEM AND DISORDERS OF BILIRUBIN METABOLISM |
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Chapter 75 |
Developmental Biology of the Hematologic System Annie Nguyen-Vermillion and Sandra E. Juul |
1047 |
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Chapter 76 |
Hemostatic Disorders of the Newborn Guy Young |
1056 |
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Chapter 77 |
Erythrocyte Disorders in Infancy Dana C. Matthews and Bertil Glader |
1080 |
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Chapter 78 |
Neonatal Leukocyte Physiology and Disorders Evan B. Shereck, Carmella van de Ven and Mitchell S. Cairo |
1108 |
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Chapter 79 |
Neonatal Indirect Hyperbilirubinemia and Kernicterus Jon F. Watchko |
1123 |
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PART XVI |
NEOPLASIA |
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Chapter 80 |
Congenital Malignant Disorders Elizabeth Robbins, Mignon L Loh and Katherine K. Matthay |
1143 |
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PART XVII |
RENAL AND GENITOURINARY SYSTEMS |
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Chapter 81 |
Renal Morphogenesis and Development of Renal Function Jean-Pierre Guignard and Endre Sulyok |
1165 |
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Chapter 82 |
Clinical
Evaluation of Renal and Urinary Tract
Disease |
1176 |
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Chapter 83 |
Developmental
Abnormalities of the Kidneys |
1182 |
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Chapter 84 |
Developmental Abnormalities of the Genitourinary System Stephen A. Zderic and Sarah M. Lambert |
1191 |
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Chapter 85 |
Acute Kidney Injury and Chronic Kidney Disease David Askenazi, Lorie B. Smith, Susan Furth and Bradley A. Warady |
1205 |
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Chapter 86 |
Glomerulonephropathies and Disorders of Tubular Function |
1222 |
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Chapter 87 |
Urinarytract Infections and Vesicoureteral
Reflux Stephen A. Zderic |
1228 |
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Chapter 88 |
Renal Vascular Disease in the Newborn Halima Saadia Janjua and Donald L. Batisky |
1235 |
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PART XVIII |
ENDOCRINE DISORDERS |
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Chapter 89 |
Embryology,
Developmental Biology, and Anatomy of the Endocrine System Lewis P. Rubin |
1245 |
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Chapter 90 |
Disorders of
Calcium and Phosphorus Metabolism Lewis P. Rubin |
1255 |
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Chapter 91 |
Disorders of the Adrenal Gland Saroj Nimkarn and Maria I. New |
1274 |
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Chapter 92 |
Ambiguous Genitalia in the Newborn Karen Lin-Su and Maria I. New |
1286 |
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Chapter 93 |
Disorders of the Thyroid Gland Sureka Bollepalli and Susan R. Rose |
1307 |
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Chapter 94 |
Disorders of Carbohydrate Metabolism Vandana Jain, Ming Chen and Ram K. Menon |
1320 |
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PART XIX |
CRANIOFACIAL AND ORTHOPEDIC CONDITIONS |
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Chapter 95 |
Craniofacial Malformations Kelly Evans, Anne V. Hing and Michael Cunningham |
1331 |
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Chapter 96 |
Common Neonatal Orthopedic Ailments Klane K. White and Michael J. Goldberg |
1351 |
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PART XX |
DERMATOLOGIC CONDITIONS |
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Chapter 97 |
Newborn Skin: Development and Basic Concepts Bernard A. Cohen and Katherine B. Püttgen |
1363 |
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Chapter 98 |
Congenital and Hereditary Disorders of the Skin Mark M. Tran and Bernard A. Cohen |
1373 |
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Chapter 99 |
Infections of the Skin Dakara Rucker Wright and Bernard A. Cohen |
1390 |
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Chapter 100 |
Common Newborn Dermatoses Dakara Rucker Wright and Bernard A. Cohen |
1397 |
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Chapter 101 |
Cutaneous Congenital Defects Katherine B. Piittgen and Bernard A. Cohen |
1406 |
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PART XXI |
THE EYE |
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Chapter 102 |
Disorders of the Eye Alejandra G. De Alba Campomanes, Gil Binenbaum and Graham E. Quinn |
1423 |
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