Table of Contents

 

 

 

SECTION I

CHRONIC KIDNEY DISEASE

 

Chapter 1

Chronic Kidney Disease: Definition, Epidemiology, Cost, and Outcomes   Tariq Shafi, M.B.B.S., M.H.S., F.A.C.P. and Josef Coresh, M.D., M.H.S., Ph.D.

3

Chapter 2

Measurement and Estimation of Kidney Function   Lesley A. Stevens, M.D., M.S., Cindy Huang, M.D., Ph.D. and Andrew S. Levey, M.D.

22

Chapter 3

Diabetic Kidney Disease: Current Challenges   Mark E. Williams, M.D., F.A.C.P., F.A.S.N. and Robert C. Stanton, M.D.

39

Chapter 4

Hypertensive Kidney Disease   Nitin Khosla, M.D., Rigas Kalaitzidis, M.D. and George L. Bakris, M.D.

57

Chapter 5

Chronic Kidney Disease in the Elderly   Ann M. O’Hare, M.A., M.D.

68

SECTION II

COMPLICATIONS AND MANAGEMENT OF CHRONIC KIDNEY DISEASE

 

Chapter 6

The Role of the Chronic Kidney Disease Clinic   Monica C. Beaulieu, M.D., F.R.C.P.C, M.H.A., Bryan M. Curtis, M.D., F.R.C.P.C. and Adeera Levin, M.D., F.R.C.P.C.

75

Chapter 7

Anemia in Chronic Kidney Disease   Steven M. Brunelli, M.D., M.S.C.E. and Jeffreys. Berns, M.D.

87

Chapter 8

Chronic Kidney Disease-Mineral Bone Disorder   Sharon M. Moe, M.D.

98

Chapter 9

Vitamin D Deficiency   Ian H. de Boer, M.D., M.S.

115

Chapter 10

Cardiovascular Disease in Patients with Chronic Kidney Disease   Daniel E. Weiner, M.D., M.S. and Mark J. Sarnak, M.D., M.S.

128

Chapter 11

Complications and Management of Chronic Kidney Disease: Diabetes   Katherine R. Tuttle, M.D., F.A.S.N., F.A.C.P.

145

Chapter 12

Nutrition and Metabolism in Kidney Disease   Alp Ikizler, M.D. and Lara B. Pupim, M.D., M.S.C.I.

164

Chapter 13

Inflammation in Chronic Kidney Disease   Csaba P. Kovesdy, M.D. and Kamyar Kalantar-Zadeh, M.D., M.P.H., Ph.D.

183

Chapter 14

Sleep Disorders in Chronic Kidney Disease   Maria-Eleni Roumelioti, M.D., Patrick J. Strollo Jr., M.D., F.C.C.P., F.A.A.S.M. and Mark Unruh, M.D., M.Sc.

198

Chapter 15

Kidney Disease and Medications   Wolfgang C. Winkelmayer, M.D., Sc.D.

208

Chapter 16

Depression and Neurocognitive Function in Chronic Kidney Disease   Daniel Cukor, Ph.D., Deborah S. Rosenthal, M.A., and Paul L. Kimmel, M.D.

218

Chapter 17

The Pediatric Patient with Chronic Kidney Disease   Bradley A. Warady, M.D. and Vimal Chadha, M.D.

231

Chapter 18

The Pathophysiology of Uremia   Matthew K. Abramowitz, M.D., M.S., Timothy W. Meyer, M.D., and Thomas H. Hostetter, M.D.

251

Chapter 19

Timing and Initiation and Modality Options for Renal Replacement Therapy   Bessie Ann Young, M.D., M.P.H.

265

SECTION III

HEMODIALYSIS

 

Chapter 20

Principles of Hemodialysis   Jane Y. Yeun, M.D., and Thomas A. Depner, M.D.

277

Chapter 21

Vascular Access   Bradley S. Dixon, M.D. and Laura M. Dember, M.D.

303

Chapter 22

Hemodialysis Adequacy   John K. Leypoldt, Ph.D., Bruce F. Culleton, M.D., F.R.C P.C. and Alfred K. Cheung, M.D.

320

Chapter 23

Hemodialysis-Associated Infections   Matthew J. Arduino, M.S., Dr.P.H., Priti R. Patel, M.D., M.P.H., Nicola D. Thompson, Ph.D. and Martin S. Favero, Ph.D.

335

Chapter 24

Acute Complications Associated with Hemodialysis   Orfeas Liangos, M.D., F.A.C.P., F.A.S.N., and Betrand L. Jaber, M.D., M.S., F.A.S.N.

354

Chapter 25

Frequent Hemodialysis: Physiological, Epidemiological, and Practical Aspects   Rita S. Suri, M.D. and Alan S. Kliger, M.D.

370

SECTION IV

PERITONEAL DIALYSIS

 

Chapter 26

Peritoneal Physiology   Olof Heimbürger, M.D., Ph.D

387

Chapter 27

The Utilization and Outcome of Peritoneal Dialysis   Yi-Wen Chiu, M.D. and Rajnish Mehrotra, M.D

405

Chapter 28

Peritoneal Dialysis Solutions   Simonj. Davies, M.D.

417

Chapter 29

Peritoneal Dialysis Prescription and Adequacy   Peter G. Blake, M.B., F.R.C P.C. F.R.C.P.I. and Rita S. Suri, M.D.

432

Chapter 30

Peritoneal Dialysis-Related Infections   Szeco Cheuk Chun, M.D., F.R.C.P. and Philip Kam-Tao Li, M.D., F.R.C.P, F.A.C.P.

446

Chapter 31

Noninfectious Complications of Peritoneal Dialysis   Ziv Harel, M.D., F.R.C.P.C and Joanne M. Bargman, M.D., F.R.C.P.C

459

SECTION V

TRANSPLANTATION

 

Chapter 32

Transplantation Immunobiology   Nader Najafian, M.D., and Mohamed H. Sayegh, M.D.

477

Chapter 33

Evaluation of Donors and Recipients   Colm C. Magee, M.D., M.P.H., F.R.C.P.I.

491

Chapter 34

Surgical Management of the Renal Transplant Recipient   Sayeed K. Malek, M.D., F.A.C.S. and Stefan G. Tullius, M.D., Ph.D., F.A.C.S.

502

Chapter 35

Biological Agents in Kidney Transplantation   Edmund Huang, M.D., Karl L. Womer, M.D., and Flavio Vincenti, M.D.

509

Chapter 36

Current and Emerging Maintenance Immunosuppressive Therapy   Simin Goral, M.D., and J. Harold Helderman, M.D.

516

Chapter 37

Diagnosis and Therapy of Graft Dysfunction   Phuong-Thu T. Pham, M.D., Cynthia C. Nasc, M.D., Phuong-Chi T. Pham, M.D. and Gabriel Danovitch, M.D.

526

Chapter 38

Infection in Renal Transplant Recipients   Camile Nelson Kotton, M.D., and Emilio Ramos, M.D.

553

Chapter 39

Noninfectious Complications After Kidney Transplantation   Monica Grafals, M.D. John P. Vella, M.D., F.R.C.P., F.A.C.P., F.A.S.N. and Anil Chandraker, M.D., F.R.C.P.

568

Chapter 40

Recurrent and De Novo Renal Diseases After Kidney Transplantation   Denise M. Sadlier, M.B., Ph.D., F.R.C.P.I., and Yvonne M. O’Meara, M.D., F.R.C.P.I.

580

Chapter 41

Pediatric Renal Transplantation   William E. Harmon, M.D.

591

Chapter 42

Novel Diagnostics in Transplantation   M. Javeed Ansari, M.D., and Terry B. Strom, M.D.

609

Chapter 43

Chronic Kidney Disease in Nonkidney Transplant Recipients: Hematopoietic Cell and Solid Organ Transplantation   Akinlolu O. Ojo, M.D., Ph.D.

620

Chapter 44

Emerging Strategies in Kidney Transplantation   Marilia Cascalho, M.D., Ph.D., and Jeffrey L. Platt, M.D.

628

Chapter 45

Chronic Kidney Disease and the Kidney Transplant Recipient   John S. Gill, M.D., F.R.C.P.C., M.S., and Olwyn Johnston, M.B., M.R.C.P.I., M.D., M.H.Sc.

636

SECTION VI

ACUTE KIDNEY INJURY

 

Chapter 46

The Epidemiology of Acute Kidney Injury   Sushrut S. Waikar, M.D., M.P.H., and Jonathan Himmelfarb, M.D.

643

Chapter 47

Metabolic and Nutritional Complications of Acute Kidney Injury   Edward D. Siew, M.D., M.S.C.I., and Jonathan Himmelfarb, M.D.

654

Chapter 48

Acute Kidney Injury: Biomarkers from Bench to Bedside   Joseph V. Bonventre, M.D., Ph.D., and Venkata Sabbisetti, Ph.D.

668

Chapter 49

Pharmacological Interventions in Acute Kidney Injury   Mark Douglas Okusa, M.D., and Rasheed Abiodun Balogun, M.D.

677

Chapter 50

Dialytic Management for Acute Renal Failure   Etienne Macedo, M.D., Glenn M. Chertow, M.D., M.P.H. and Ravindra L. Mehta, M.D.

687

Chapter 51

Extracorporeal Treatment of Poisonings   Stuart Abramson, M.D., M.P.H

700

 

Index

721