Table of Contents

 

 

 

PART I

NEONATAL HEMODYNAMICS

 

SECTION A

PRINCIPLES OF DEVELOPMENTAL CARDIOVASCULAR PHYSIOLOGY AND PATHOPHYSIOLOGY

 

Chapter 1

Principles of Developmental Cardiovascular Physiology and Pathophysiology   Shahab Noori MD, RDCS; Theodora A. Stavroudis, MD; and Istvan Seri, MD, PhD, HonD

3

Chapter 2

Autoregulation of Vital and Nonvital Organ Blood Flow in the Preterm and Term Neonate   Gorm Greisen, MD, PhD

29

Chapter 3

Definition of Normal Blood Pressure Range: The Elusive Target   William D, Engle, MD

49

SECTION B

DIAGNOSIS OF NEONATAL SHOCK: METHODS AND THEIR CLINICAL APPLICATIONS

 

Chapter 4

Methods to Assess Systemic and Organ Blood Flow in the Neonate   Gorm Greisen, MD, PhD

81

Chapter 5

Functional Echocardiography in the Neonatal Intensive Care Unit   Nicholas J. Evans, DM, MRCPCH

95

Chapter 6

Assessment of Cardiac Output in Neonates: Techniques Using the Fick Principle, Pulse Wave Form Analysis, and Electrical Impedance   Markus Qsyoka, PhD; Sadaf Soleymani, MS; Istvan Seri, MD, PhD, HonD; and Shahab Noori, MD RDCS

125

Chapter 7

Near-Infrared Spectroscopy and Its Use for the Assessment of Tissue Perfusion in the Neonate   Suresh Victor, PhD, MRCPCH, and Michael Weindling, MD, FRCP, FRCPCH, Hon FRCA

151

Chapter 8

Clinical Applications of Near-Infrared Spectroscopy in Neonates   Petra Lemmers, MD, PhD; Gunnar Naulaers, MD, PhD; and Frank van Bell, MD, PhD

173

Chapter 9

Advanced Magnetic Resonance Neuroimaging Techniques in the Neonate with a Focus on Hemodynamic-Related Brain Injury   Matthew Borzage, MS; Ashok Panigrahy, MD; and Stefan Blüml, PhD

187

Chapter 10

Cardiovascular Magnetic Resonance in the Study of Neonatal Hemodynamics   Anthony N. Price, PhD, and Alan M. Groves, MD, FRCPCH

199

Chapter 11

Assessment of the Microcirculation in the Neonate   Ian M. R. Wright, MBBS, DCH, MRCP(Paeds)UK, FRACP; Michael J. Stark PhD, MRCP; and Vicki L Clifton, PhD

215

SECTION C

CLINICAL PRESENTATIONS AND RELEVANCE OF NEONATAL SHOCK

 

Chapter 12

Clinical Presentations of Neonatal Shock: The Very Low Birth Weight Neonate during the First Postnatal Day   Martin Kluckow, PhD, MBBS, FRACP, and Istvan Seri, MD, PhD, HonD

237

Chapter 13

The Very Low Birth Weight Neonate with Hemodynamically Significant Ductus Arteriosus During the First Postnatal Week   Ronald Clyman, MD, and Shahab Noori, MD, RDCS

269

Chapter 14

The Preterm Neonate with Cardiovascular and Adrenal Insufficiency   Erika F. Fernandez, MD, and Cynthia H. Cole, MD, MPH

293

Chapter 15

Shock in the Surgical Neonate   Philippe S. Friedlich, MD, MS Epi, MBA; Cathy Shin, MD, FACS, FAAP; James Stein, MD, FACS, FAAP; and Istvan Seri, MD, PhD, HonD

311

Chapter 16

Hemodynamics and Brain Injury in the Preterm Neonate   Adré J. du Plessis, MBChB, MPH

321

PART II

FETAL AND NEONATAL CARDIOLOGY

 

SECTION D

EMBRYONIC AND FETAL DEVELOPMENT

 

Chapter 17

The Genetics of Fetal and Neonatal Cardiovascular Disease   Wendy Chung, MD, PhD; Marko T. Boskovski, MD; Martina Brueckner, MD; Kwame Anyane-Yeboa, MD; and Punita Gupta, MD

343

Chapter 18

Human Cardiac Development in the First Trimester   Preeta Dhanantwari, MD; Linda Leatherbury, MD; Cecilia W. Lo, PhD; and Mary T, Donofrio, MD, FAAP, FACC, FASE

377

Chapter 19

The Reappraisal of Normal and Abnormal Cardiac Development   Robert H. Anderson, MD, FRCPath; Nigel A. Brown, PhD; Bill Chaudhry, MB, ChB, PhD; Deborah J. Henderson, PhD; Simon D. Bamforth, PhD; Timothy J. Mohun, PhD; and Antoon F. M. Moorman, PhD

391

SECTION E

FETAL AND NEONATAL CARDIOLOGY

 

Chapter 20

New Concepts for Training the Pediatric Cardiology Workforce of the Future   Arthur Garson, Jr., MD, MPH

417

Chapter 21

The Current Role of Fetal Echocardiography   1Charles S. Kleinman, MD; Julie S. Glickstein, MD; Ganga Krishnamurthy, MD; and Jodie K. Votava-Smith, MD

431

Chapter 22

Clinical Evaluation of Cardiovascular Function in the Human Fetus   James Huhta, MD

443

Chapter 23

Cardiac Surgery in the Neonate with Congenital Heart Disease   Emile Bacha, MD, FACS; Jonathan M. Chen, MD; and Jan M. Quaegebeur, MD, PhD

453

Chapter 24

Regional Blood Flow Monitoring in the Perioperative Period   George M. Hoffman, MD FACS, and James S. Tweddell, MD

473

Chapter 25

Mechanical Pump Support and Cardiac Transplant in the Neonate   Marc E. Richmond, MD

489

Chapter 26

Catheter-Based Therapy in the Neonate with Congenital Heart Disease   Shabana Shahanavaz, MD; Ziyad M. Hijazi, MD, MPH; William E. Hellenbrand, MD; and Julie Anne Vincent, MD, FACC, FAAP

503

Chapter 27

Hybrid Management Techniques in the Treatment of the Neonate with Congenital Heart Disease   Damien Kenny, MD; Mark Galantowicz, MD; John P. Cheatham, MD; and Ziyad M. Hijazi, MD, MPH

521