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PART I |
MOLECULAR AND CELLULAR BASIS OF HEMATOLOGY |
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1 |
Anatomy and Pathophysiology of the Gene |
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2 |
Genomic Approaches to Hematology |
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3 |
Regulation of Gene Expression, Transcription, Splicing, and RNA Metabolism |
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4 |
Protein Synthesis, Processing, and Trafficking |
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5 |
Protein Architecture: Relationship of Form and Function |
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6 |
Signaling Transduction and Regulation of Cell Metabolism |
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7 |
Pharmacogenomics and Hematologic Diseases |
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PART II |
CELLULAR BASIS OF HEMATOLOGY |
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8 |
Hematopoietic Stem Cell Biology |
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9 |
Hematopoietic Microenvironment |
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10 |
Cell Adhesion |
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11 |
Hematopoietic Cell Trafficking and Chemokines |
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12 |
Dynamic Interactions between Hematopoietic Stem and Progenitor Cells and the Bone Marrow: Current Biology of Stem Cell Homing and Mobilization |
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13 |
Vascular Growth in Health and Disease |
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14 |
Principles of Cytokine Signaling |
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15 |
Control of Cell Division |
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16 |
Cell Death |
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PART III |
IMMUNOLOGIC BASIS OF HEMATOLOGY |
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17 |
Overview and Compartmentalization of the Immune System |
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18 |
B-Cell Development |
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19 |
T-Cell Immunity |
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20 |
Natural Killer Cell Immunity |
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21 |
Dendritic Cell Biology |
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22 |
Complement and Immunoglobulin Biology |
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23 |
Tolerance and Autoimmunity |
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PART IV |
DISORDERS OF HEMATOPOIETIC CELL DEVELOPMENT |
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24 |
Biology of Erythropoiesis, Erythroid Differentiation, and Maturation |
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25 |
Granulocytopiesis and Monocytopoiesis |
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26 |
Thrombocytopoiesis |
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27 |
Inherited Forms of Bone Marrow Failure |
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28 |
Aplastic Anemia |
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29 |
Paroxysmal Nocturnal Hemoglobinuria |
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30 |
Acquired Disorders of Red Cell, White Cell, and Platelet Production |
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PART V |
RED BLOOD CELLS |
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31 |
Pathobiology of the Human Erythrocyte and Its Hemoglobins |
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32 |
Approach to Anemia in the Adult and Child |
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33 |
Pathophysiology of Iron Homeostasis |
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34 |
Disorders of Iron Homeostasis: Iron Deficiency and Overload |
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35 |
Anemia of Chronic Diseases |
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36 |
Heme Biosynthesis and Its Disorders: Porphyrias and Sideroblastic Anemias |
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37 |
Megaloblastic Anemias |
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38 |
Thalassemia Syndromes |
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39 |
Pathobiology of Sickle Cell Disease |
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40 |
Sickle Cell Disease - Clinical Features and Management |
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41 |
Hemoglobin Variants Associated with Hemolytic Anemia, Altered Oxygen Affinity, and Methemoglobinemias |
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42 |
Red Blood Cell Enzymopathies |
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43 |
Red Blood Cell Membrane Disorders |
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44 |
Autoimmune Hemolytic Anemia |
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45 |
Extrinsic Nonimmune Hemolytic Anemias |
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PART VI |
NON-MALIGNANT LEUKOCYTES |
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46 |
Neutrophilic Leukocytosis, Neutropenia, Monocytosis and Monocytopenia |
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47 |
Lymphocytosis, Lymphocytopenia, Hypergammaglobulinemia and Hypogammaglobulinemia |
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48 |
Disorders of Phagocyte Function |
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49 |
Congenital Disorders of Lymphocyte Function |
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50 |
Histiocytic Disorders |
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51 |
Lysosomal Storage Diseases: Perspectives and Principles |
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52 |
Infectious Mononucleosis and Other Epstein-Barr Virus-Associated Diseases |
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PART VII |
HEMATOLOGIC MALIGNANCIES |
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53 |
Progress in the Classification of Myeloid Neoplasms: Clinical Implications |
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54 |
Conventional and Molecular Cytogenetic Basis of Hematologic Malignancies |
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55 |
Pharmacology and Molecular Mechanisms of Antineoplastic Agents for Hematologic Malignancies |
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56 |
Radiation Therapy in the Treatment of Hematologic Malignancies |
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57 |
Pathobiology of Acute Myeloid Leukemia |
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58 |
Clinical Manifestations and Treatment of Acute Myeloid Leukemia |
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59 |
Myelodysplastic Syndromes: Biology and Treatment |
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60 |
Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome in Adults |
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61 |
Acute Myeloid Leukemia in Children |
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62 |
Myelodysplastic and Myeloproliferative Neoplasms in Children |
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63 |
Pathobiology of Acute Lymphoblastic Leukemia |
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64 |
Clinical Manifestations and Treatment of Acute Lymphoblastic Leukemia in Children |
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65 |
Acute Lymphoblastic Leukemia in Adults |
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66 |
Chronic Myeloid Leukemia |
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67 |
The Polycythemias |
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68 |
Essential Thrombocythemia |
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69 |
Primary Myelofibrosis |
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70 |
Eosinophilia, Eosinophil-Associated Diseases, Chronic Eosinophil Leukemia, and the Hypereosinophilic Syndromes |
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71 |
Mast Cells and Systemic Mastocytosis |
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72 |
The Pathologic Basis for the Classification of Non-Hodgkin and Hodgkin Lymphomas |
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73 |
Origins of Hodgkin Lymphoma |
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74 |
Hodgkin Lymphoma: Clinical Manifestations, Staging, and Therapy |
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75 |
Origin of Non-Hodgkin Lymphoma |
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76 |
Chronic Lymphocytic Leukemia |
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77 |
Hairy Cell Leukemia |
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78 |
Clinical Manifestations and Treatment of Marginal Zone Lymphomas (Extranodal/Malt, Splenic, and Nodal) |
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79 |
Clinical Manifestations, Staging, and Treatment of Follicular Lymphoma |
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80 |
Mantle Cell Lymphoma |
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81 |
Diagnosis and Treatment of Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma |
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82 |
Virus-Associated Lymphoma |
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83 |
Malignant Lymphomas in Childhood |
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84 |
T-Cell Lymphomas |
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85 |
Plasma Cell Neoplasms |
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86 |
Waldenstrom Macroglobulinemia and Lymphoplasmacytic Lymphoma |
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87 |
Immunoglobuin Light-Chain Amyloidosis (Primary Amyloidosis) |
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PART VIII |
COMPREHENSIVE CARE OF PATIENTS WITH HEMATOLOGIC MALIGNANCIES |
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Clinical Approach to Infections in the Compromised Host |
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89 |
Indwelling Access Devices |
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90 |
Nutritional Issues in Patients with Hematologic Malignancies |
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91 |
Psychosocial Aspects of Hematologic Disorders |
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92 |
Pain Management and Antiemetic Therapy in Hematologic Disorders |
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93 |
Palliative Care |
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94 |
Late Complications of Hematologic Diseases and Their Therapies |
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PART IX |
CELL-BASED THERAPIES |
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95 |
Overview and Historical Perspective of Cell-Based Therapies |
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96 |
Practical Aspects of Hematologic Stem Cell Harvesting and Mobilization |
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97 |
Preclinical Process of Cell-Based Therapies |
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98 |
Graft Engineering and Cell Processing |
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99 |
Principles of Cell-Based Genetic Therapies |
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100 |
Mesenchymal Stromal Cells |
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101 |
T Cell Therapy of Hematological Diseases |
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102 |
Natural Killer Cell-Based Therapies |
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103 |
Dendritic Cell Therapies |
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PART X |
TRANSPLANTATION |
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104 |
Overview of Hematopoietic Cell Transplantation |
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105 |
Indications and Outcome of Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies in Adults |
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106 |
Unrelated Donor Hematopoietic Cell Transplantation |
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107 |
Haploidentical Hematopoietic Cell Transplantation |
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108 |
Unrelated Donor Cord Blood Transplantation for Hematologic Malignancies |
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109 |
Graft-versus-Host Disease and Graft-versus-Leukemia Responses |
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110 |
Complications After Hematopoietic Stem Cell Transplantation |
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PART XI |
TRANSFUSION MEDICINE |
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111 |
Human Blood Group Antigens and Antibodies |
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112 |
Principles of Red Blood Cell Transfusion |
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113 |
Principles of Platelet Transfusion Therapy |
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114 |
Human Leukocyte Antigen and Human Neutrophil Antigen Systems |
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115 |
Principles of Neutrophil (Granulocyte) Transfusions |
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116 |
Principles of Plasma Transfusion: Plasma, Cryoprecipitate, Albumin, and Immunoglobulins |
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117 |
Preparation of Plasma-Derived and Recombinant Human Plasma Proteins |
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118 |
Transfusion Therapy for Coagulation Factor Deficiencies |
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119 |
Hemapheresis |
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120 |
Transfusion Reactions to Blood and Cell Therapy Products |
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121 |
Transfusion-Transmitted Diseases |
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122 |
Transfusion Medicine in Hematopoietic Stem Cell and Solid Organ Transplantation |
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123 |
Pediatric Transfusion Medicine |
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PART XII |
HEMOSTASIS AND THROMBOSIS |
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124 |
Overview of Hemostasis and Thrombosis |
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125 |
The Blood Vessel Wall |
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126 |
Megakaryocyte and Platelet Structure |
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127 |
Molecular Basis for Platelet Function |
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128 |
Molecular Basis of Blood Coagulation |
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129 |
Regulatory Mechansims in Hemostasis |
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130 |
Clinical Approach to the Patient with Bleeding or Bruising |
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131 |
Laboratory Evaluation of Hemostatic and Thrombotic Disorders |
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132 |
Acquired Disorders of Platelet Function |
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133 |
Diseases of Platelet Number: Immune Thrombocytopenia, Neonatal Alloimmune Thrombocytopenia, and Posttransfusion Purpura |
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134 |
Thrombocytopenia Caused by Platelet Destruction, Hypersplenism, or Hemodilution |
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135 |
Heparin-Induced Thrombocytopenia |
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136 |
Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic Syndrome |
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137 |
Hemophilia A and B |
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138 |
Inhibitors in Hemophilia A and B |
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139 |
Rare Coagulation Factor Deficiencies |
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140 |
Structure, Biology, and Genetics of von Willebrand Factor |
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141 |
Disseminated Intravascular Coagulation |
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142 |
Hypercoagulable States |
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143 |
Antiphospholipid Syndrome |
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144 |
Venous Thromboembolism |
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145 |
Mechanical Interventions in Arterial and Venous Thrombosis |
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146 |
Atherothrombosis |
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147 |
Stroke |
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148 |
Acute Coronary Syndromes |
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149 |
Atrial Fibrillation |
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150 |
Peripheral Artery Disease |
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151 |
Antithrombotic Drugs |
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152 |
Disorders of Coagulation in the Neonate |
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PART XIII |
CONSULTATIVE HEMATOLOGY |
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153 |
Hematologic Changes in Pregnancy |
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154 |
Hematologic Manifestations of Childhood Illness |
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155 |
Hematologic Manifestations of Liver Disease |
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156 |
Hematologic Manifestations of Systemic Disease: Renal Disease |
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157 |
Hematologic Manifestations of Cancer |
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158 |
Integrative Therapies in Patients with Hematologic Diseases |
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159 |
Hematologic Manifestations of HIV/AIDS |
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160 |
Hematologic Aspects of Parasitic Diseases |
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161 |
Hematologic Problems in the Surgical Patient: Bleeding and Thrombosis |
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162 |
The Spleen and Its Disorders |
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163 |
Hematology in Aging |
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164 |
(Online Only) Resources For The Hematologist: Interpretive Comments and Selected Reference Values for Neonatal, Pediatric, and Adult Populations |
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