Table of Contents

 

 

 

UNIT I

SENSE OF BEING: THE CONCEPT OF SELF AND SELF/NONSELF RECOGNITION

 

Chapter 1

The Need for Self-Recognition

1

Chapter 2

Antigens and Receptors

11

UNIT II

THE INNATE IMMUNE SYSTEM

 

Chapter 3

Barriers to Infection

25

Chapter 4

Cells of the Innate Immune System

34

Chapter 5

Innate Immune Function

42

UNIT III

THE ADAPTIVE IMMUNE SYSTEM

 

Chapter 6

Molecules of Adaptive Immunity

59

Chapter 7

Cells and Organs

79

Chapter 8

Generation of Immune Diversity: Lymphocyte Antigen Receptors

91

Chapter 9

Lymphocyte Development

113

Chapter 10

Lymphocyte Activation

123

Chapter 11

Lymphocyte Effector Functions

141

Chapter 12

Regulation of Adaptive Responses

158

UNIT IV

CLINICAL ASPECTS OF IMMUNITY

 

Chapter 13

The Well Patient: How Innate and Adaptive Immune Responses Maintain Health

169

Chapter 14

Hypersensitivity Reactions

200

Chapter 15

Immune Deficiency

219

Chapter 16

Autoimmunity

243

Chapter 17

Transplantation

260

Chapter 18

Immune Pharmacotherapy

283

Chapter 19

Tumor Immunity

298

Chapter 20

Measurement of Immune Function

312

 

Review Questions

330

 

Abbreviations

343

 

Glossary

348

 

Index

371