Table of Contents

 

 

 

SECTION I

INTRODUCTION TO IMMUNOLOGY

 

1

The Immune System   William E. Paul

 

2

History of Immunology   Steven Greenberg Ii

 

SECTION II

ORGANIZATION AND EVOLUTION OF THE IMMUNE SYSTEM

 

3

Lymphoid Tissues and Organs   Eitan M. Akirav, Noelia Alonso-Gonzalez, Lucy A. Truman, and Nancy H. Ruddle

 

4

Evolution of the Immune System   Martin F. Flajnik

 

SECTION III

IMMUNOGLOBULINS AND B LYMPHOCYTES

 

5

Immunoglobulins: Structure and Function   Harry W. Schroeder

 

 

Immunoglobulins: Molecular Genetics   Edward E. Max and Sebastian Fugmann

 

7

Antigen-Antibody Reactions   Jay A. Berzofsky and Ira Berkower

 

8

B Lymphocyte Development   Richard R. Hardy

 

9

B Lymphocyte Receptors, Signaling Mechanisms, and Activation   Akanksha Chaturvedi, Angel Davey, Wanli Liu, Hae Won Sohn, and Susan K. Pierce

 

10

B Lymphocyte Responses   Michael McHeyzer-Williams

 

SECTION IV

T LYMPHOCYTES

 

11

T Lymphocyte Receptors   Mark M. Davis

 

12

T Lymphocyte Signaling Mechanisms   Takashi Saito

 

13T

Lymphocyte Developmental Biology   Ellen V. Rothenberg and Ameya Champhekar

 

14

Peripheral T Lymphocyte Responses and Function   Marc K. Jenkins

 

SECTION V

THE INTERSECTION OF INNATE AND ADAPTIVE IMMUNITY

 

15

The Innate Immune System   Luke A. J. O’Neill

 

16

Dendritic Cells   Michel C. Nussenzweig

 

17

Natural Killer Cells   Wayne M. Yokoyama

 

18

CD1d-restricted NKT Cells   Albert S. Bendelac

 

19

Macrophages and Phagocytosis   Siamon Gordon

 

20

Granulocytes and Mast Cells   Patrizia Scapini, Nicola Tamassia, Carlo Pucillo, and Marco A. Cassatella

 

21

The Major Histocompatibility Complex and its Proteins   David H. Margulies

 

22

Antigen Processing and Presentation   Ted H. Hansen and Paul A. Roche

 

SECTION VI

INDUCTION, REGULATION, AND EFFECTOR FUNCTIONS OF THE IMMUNE RESPONSE

 

23

Immunogenicity and Antigen Structure   Jay A. Berzofsky

 

24

Fc Receptors and Their Role in Immune Regulation and Inflammation   Jeffrey V. Ravetch and Falk Nimmerjahn

 

25

Type I Cytokines and Interferons   Warren J. Leonard

 

26

Interleukin-1 Family Cytokines   Charles A. Dinarello and Mihai G. Netea

 

27

TNF-related Cytokines in Immunity   Carl F. Ware

 

28

Chemokines   Philip M. Murphy

 

29

Helper T Cell Differentiation and Plasticity   John J. O’Shea

 

30

Programmed Cell Death   Andrew L. Snow and Michael J. Lenardo

 

31

Immunological Memory   Shane Crotty, Susan M. Kaech, and Stephen P. Schoenberger

 

32

Immunological Tolerance   Pamela S. Ohashi

 

33

Regulatory/Suppressor T Cells   Ethan M. Shevach

 

34

Mucosal Immunity and Microbiome   Yasmine Belkaid

 

35

Neurophysiological Reflex Mechanisms in Immunology   Chavan and Kevin J. Tracey

 

36

Complement   

 

37

Cell-mediated Cytotoxicity   Judy Lieberman

 

SECTION VII

IMMUNITY TO INFECTIOUS AGENTS

 

38

The Immune Response to Parasites   Thomas A. Wynne, David L. Sacks, Alan Sher, and Eleanor M. Riley

 

39

Immunity to Viruses   Hildegund C.J. Ertl

 

40

Immunity to Intracellular Bacteria   Anca Dorhoi, Stephen T. Reece, and Stefan H. E. Kaufmann

 

41

Immunity to Extracellular Bacteria   Moon H. Nahm and Jannet Katz

 

42

Immunology of HIV Infection   Bruce Walker

 

43

Vaccines   Ennio De Gregorio, Ugo D’Oro, Sylvie Bertholet, and Rino Rappuoli

 

SECTION VIII

IMMUNOLOGIC MECHANISMS IN DISEASE

 

44

Organ-Specific Autoimmunity   Ken T. Coppieters, Matthias G. von Herrath, and Dirk Homann

 

45

Allergy   Marsha Wills-Karp

 

46

Transplantation Immunology   Megan Sykes

 

47

Cancer Immunology   Hans Schreiber

 

48

Inborn Errors of Immunity   Jean-Laurent Casanova, Mary Ellen Conley, and Luigi D. Notarangelo