Table of Contents

 

 

 

 

Preface

vii

 

Acknowledgments

ix

 

Contributors

xi

1

Part 1: Molecular Biology of Cancer   Robert A. Kratzke

1

2

Part 2: Molecular Biology of Cancer   Sunit Srivatsava and George R. Simon

18

3

Part 1: Etiology of Cancer   Shirish M. Gadgeel

33

4

Part 2: Etiology of Cancer   Nikhil I. Khushalani and Kaunteya Reddy

56

5

Epidemiology of Cancer   Thomas E. Stinchcombe

69

6

Principles of Surgical Oncology   Rebecca L. Aft and Jason Keune

76

7

Principles of Radiation Oncology   Hak Choy and L. Chinsoo Cho

81

8

Principles of Medical Oncology   Sujatha Murali and Suresh S. Ramalingam

91

9

Principles of Immunotherapy   Sara K. Butler

100

10

Principles of Health Services Research   Boone W. Goodgame

107

11

Systemic Therapy for Cancer   Richard A. Walgren

114

12

Design and Analysis of Clinical Trials   Feng Goo and Kathryn Trinkaus

128

13

Cancer Prevention   Daniel Morgensztern and Vorachart Auethavekiat

140

14

Genetic Counseling   Jennifer Ivanovich

147

15

Cancer Screening   Megan E. Wren

162

16

Advances in Diagnostics   Sanjeev Bhalla and Cylen Javidan-Nejad

168

17

Cancer of the Head and Neck   David I. Kuperman

190

18

Cancer of the Lung   Janessa J. Laskin

198

19

Neoplasms of the Mediastinum   Gregory P. Kalemkerian

210

20

Cancer of the Gastrointestinal Tract

224

SECTION 1

ESOPHAGUS AND STOMACH   Renuka V. Iyer

224

SECTION 2

PANCREAS   Renuka V. Iyer

236

SECTION 3

HEPATOBILIARY   Renuka V. Iyer

243

SECTION 4

SMALL INTESTINE AND GASTROINTESTINAL STROMAL TUMORS   Benjamin R. Tan, Jr.

249

SECTION 5

COLORECTAL AND ANAL CANCERS   Benjamin R. Tan, Jr.

257

21

Genitourinary Cancer   Walter M. Stadler

265

22

Cancer of the Testis   Daniel Morgensztern

284

23

Gynecologic Cancers

293

SECTION 1

OVARIAN   David G. Mutch

293

SECTION 2

NONOVARIAN   Matthew A. Powell

300

24

Cancer of the Breast   Kathy D. Miller

317

25

Cancer of the Endocrine System   Rami Y. Haddad and Mouhammed Amir Habra

336

26

Sarcomas   Douglas R. Adkins, Becky J. Ganz, and Tani B. Rachocki

350

27

Benign and Malignant Mesothelioma   Maria Q. Baggstrom

359

28

Cancer of the Skin and Melanoma   Gerald P. Linette

364

29

Neoplasms of the Central Nervous System   Janakiraman Subramanian

371

30

Cancers of Childhood   Shalini Shenoy

380

31

Lymphomas   Camille N. Abboud

399

32

Acute Leukemias   John Welch and Amanda F. Cashen

423

33

Chronic Leukemias   James C. Mosley III and Keith Stockerl-Goldstein

435

34

Plasma Cell Neoplasms   Ravi Vij and Giridharan Ramsingh

444

35

Paraneoplastic Syndromes   C. Daniel Kingsley and Michael C. Perry

449

36

Cancer of Unknown Primary Site   Sunny Wang and Sarita Dubey

456

37

Peritoneal Carcinomatosis   Andrea Wang-Gillam, and David D. Tran

465

38

Immunosuppression-Related Maligancies   Lee Ratner

474

39

Oncologic Emergencies   Giridharan Ramsingh and Daniel Morgenszlern

477

40

Treatment of Metastatic Cancer   Arkadiusz Z. Dudek

483

41

Stem Cell Transplantation   Mark A. Schroeder and Peter Westervelt

501

42

Infections in Cancer Patients   Alex E. Denes

514

43

Management of Adverse Effects of Treatment   Maria Q. Baggstrom

524

44

Supportive Care and Quality of Life   Anna Roshal

532

45

Rehabilitation of the Cancer Patient   Janakiraman Subramanian

546

46

Societal Issues in Oncology   Thomas H. Fong

551

47

Information Systems in Oncology   Howard L. West

558

48

Complementary, Alternative, and Integrative Therapies in Cancer Care   Vamsidhar Velcheti

566

49

New Approaches in Cancer Treatment   Nithya Ramnath, Anubha Bharthuar, and Krishnan Raghavendran

572