Table
of Contents
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Dedication |
iii |
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Preface for
the Fourth Edition |
v |
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Contributors |
vii |
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Acknowledgments |
xv |
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SECTION I |
APPLIED EPIDEMIOLOGY AND BIOSWISTICS IN HEALTHCARE
EPIDEMIOLOGY AND INFECTION CONTROL |
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Chapter 1 |
Principles
of Infectious Diseases Epidemiology |
1 |
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Chapter 2 |
Modern
Quantitative Epidemiology in the Healthcare Setting Jerome I. Tokars |
20 |
|
Chapter 3 |
Biostatistics
for Healthcare Epidemiology and Infection Control Elizabeth A.
Tolley |
49 |
|
Chapter 4 |
Principles
of Healthcare Epidemiology Mary
D. Nettleman, Robin L. Roach, and Richard P. Wenzel |
82 |
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Chapter 5 |
Data
Collection in Healthcare Epidemiology Stephen
B. Kritchevsky and Ronald I. Shorr |
87 |
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Chapter 6 |
Practical
Application of the Principles of Epidemiology to Study Design and Data
Analysis Joseph H. Abramson |
95 |
|
Chapter 7 |
Meta-Analysis
and Systematic Reviews of the Literature in Healthcare Epidemiology and
Infection Control Nasia Safdar, Sanjay
Saint, and Mary A.M. Rogers |
114 |
|
Chapter 8 |
Investigation
of Outbreaks William R. Jarvis |
126 |
|
Chapter 9 |
Pseudoinfections and
Pseudo-Outbreaks Cheston B. Cunha and Burke A.
Cunha |
142 |
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SECTION II |
HEALTHCARE QUALITY IMPROVEMENT |
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Chapter 10 |
Creating a
Culture of Excellence Ulises Ruiz and
José Simón |
153 |
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Chapter 11 |
Selecting
Improvement Projects David
Birnbaum |
169 |
|
Chapter 12 |
Conducting
Successful Improvement Projects Marisel Segarra-Newnham
and Ronald G. Berglund |
178 |
|
Chapter 13 |
Public
Reporting of Healthcare-Associated Infections Ingi
Lee and Patrick J. Brennan |
185 |
|
Chapter 14 |
Working
with the News Media in Public Communication Marjorie Kruvand |
190 |
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SECTION III |
INFORMATICS IN HEALTHCARE EPIDEMIOLOGY |
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|
Chapter 15 |
Using the
Personal Computer for Healthcare Epidemiology John A. Sellick, Jr.,
Keith F. Woeltje, and Rebecca Wurtz |
211 |
|
Chapter 16 |
The
Electronic Health Record: an Essential Technology for Healthcare Epidemiology Andreas M. Kogelnik, Justin V.
Graham, and David C. Classen |
225 |
|
SECTION IV |
EPIDEMIOLOGY AND PREVENTION OF HEALTHCARE-ASSOCIATED
INFECTIONS OF ORGAN SYSTEMS |
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|
Chapter 17 |
Healthcare-Associated
Infections Related to the Use of Intravascular Devices Inserted for
Short-Term Vascular Access Angela
L Hewlett and Mark E. Rupp |
241 |
|
Chapter 18 |
Healthcare-Associated
Infections Related to Use of Intravascular Devices Inserted for Long-Term
Vascular Access Anne-Marie
Chaftari
and Issam Raad |
248 |
|
Chapter 19 |
Healthcare-Associated
Bloodstream Infections Trevor
C. Vanschooneveld and Mark E. Rupp |
258 |
|
Chapter 20 |
Healthcare-Associated
Urinary Tract Infections John
P. Burke and David J. Pombo |
270 |
|
Chapter 21 |
Surgical
Site Infections Sarah
Y. Won and Edward S. Wong |
286 |
|
Chapter 22 |
Healthcare-Associated
Pneumonia Dennis C.J.J. Bergmans and Marc J.M.
Bonten |
307 |
|
Chapter 23 |
Healthcare-Associated
Sinusitis Marc J.M. Bonten |
321 |
|
Chapter 24 |
Healthcare-Associated
Gastrointestinal Tract Infections Nicolas
A. Melgarejo and Herbert L. Dupont |
330 |
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Chapter 25 |
Healthcare-Associated
Burn Wound Infections C. Glen Mayhall |
338 |
|
Chapter 26 |
Healthcare-Associated
Eye Infections Marlene
L Durand, David J. Weber, and
William A. Rutala |
352 |
|
Chapter 27 |
Healthcare-Associated
Central Nervous System Infections Jeffrey
M. Tessier and W. Michael Scheld |
365 |
|
SECTION V |
EPIDEMIOLOGY AND PREVENTION OF HEALTHCARE-ASSOCIATED INFECTIONS
CAUSED BY SPECIFIC PATHOGENS |
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PART A |
BACTERIAL INFECTIONS |
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|
Chapter 28 |
Staphylococcus Aureus Joseph F. John, Jr. and
Sanjay K. Shukla |
385 |
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Chapter 29 |
Methicillin-Resistant Staphylococcus Aureus Cassandra D. Salgado and David P.
Calfee |
410 |
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Chapter 30 |
Coagulase-Negative Staphylococci Wilma Ziebuhr and
Ursula Flückiger |
443 |
|
Chapter 31 |
Mechanisms
of Biofilm
Formation in the Staphylococci Paul
D. Fey |
463 |
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Chapter 32 |
Streptococci Kent B. Crossley |
468 |
|
Chapter 33 |
Enterococcus Species Emily K. Shuman and Carol E. Chenoweth |
478 |
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Chapter 34 |
Enterobacteriaceae Stephanie R. Black, Marc J.M. Bonten, and
Robert A. Weinstein |
489 |
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Chapter 35 |
Nonfermentative Gram-Negative
Bacilli Valentina Stosor, Alan R. Hauser, and John P. Flaherty |
520 |
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Chapter 36 |
Legionella Janet E. Stout, Angella M. Goetz, and Victor L. Yu |
535 |
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Chapter 37 |
Clostridium Difficile Stuart Johnson and Dale N. Gerding |
551 |
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PART B |
MYCOBACTERIAL INFECTIONS |
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Chapter 38 |
Mycobacterium Tuberculosis William R. Jarvis |
562 |
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Chapter 39 |
Nontuberculous Mycobacteria Barbara A. Brown-Elliott and Richard J. Wallace, Jr. |
593 |
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PART C |
FUNGAL INFECTIONS |
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Chapter 40 |
Candida Michael M. Mcneil and Tom M. Chiller |
609 |
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Chapter 41 |
Filamentous
Fungi Luis Ostrosky-Zeichner
and John H. Rex |
628 |
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PART D |
VIRAL INFECTIONS |
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Chapter 42 |
Influenza
Viruses William M. Valenti |
632 |
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Chapter 43 |
Varicella-Zoster Virus John A. Zaia |
643 |
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Chapter 44 |
Herpes
Simplex Virus Stuart P. Adler |
653 |
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Chapter 45 |
Cytomegalovirus Stuart P.
Adler |
657. |
|
Chapter 46 |
Hepatitis
Viruses Adelisa L Panlilio,
Melissa K. Schaefer, and Nicola
D. Thompson |
662 |
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PART E |
OTHER PATHOGENS |
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|
Chapter 47 |
Uncommon
Causes of Healthcare-Associated Infections Michael
S. Gelfand and Kerry O. Cleveland |
675 |
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SECTION VI |
EPIDEMIOLOGY AND PREVENTION OF HEALTHCARE-ASSOCIATED
INFECTIONS IN PEDIATRIC PATIENTS |
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Chapter 48 |
Healthcare-Associated
Viral Respiratory Infections in Pediatric Patients Ronald B. Turner |
685 |
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Chapter 49 |
Healthcare-Associated
Bacterial Infections of the Central Nervous System, Upper and Lower
Respiratory Tracts, and Skin in Pediatric Patients W. Matthew
Linam and
Terry Yamauchi |
692 |
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Chapter 50 |
Healthcare-Associated
Gastrointestinal Tract Infections in Pediatric Patients Douglas K. Mitchell |
706 |
|
Chapter 51 |
Healthcare-Associated
Measles, Mumps, Rubella, and Human Parvovirus B19 Kathleen M.
Gallagher, Preeta
K. Kutty, Eileen Schneider, and Jane F. Seward |
722 |
|
Chapter 52 |
Healthcare-Associated
Infections in Newborn Nurseries and Neonatal Intensive Care Units Kristina Bryant |
737 |
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Chapter 53 |
Healthcare-Associated
Infections Acquired in Childcare Facilities Andi
L. Shane and Larry K. Pickering |
758 |
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SECTION VII |
EPIDEMIOLOGY AND PREVENTION OF HEALTHCARE-ASSOCIATED
INFECTIONS IN SPECIAL PATIENT POPULATIONS |
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Chapter 54 |
Healthcare-Associated
Infections in Dental, Oral, and Maxillofacial Surgery Cynthia J. Whitener |
775 |
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Chapter 55 |
Healthcare-Associated
Infections in Obstetric Patients Amy
Beth Kressel
and Suzanne P. Goodrich |
787 |
|
Chapter 56 |
Healthcare-Associated
Infections in Patients with Spinal Cord Injury Rabih
O. Darouiche |
795 |
|
Chapter 57 |
Healthcare-Associated
Infections in Patients with Neoplastic
Diseases Aditya H. Gaur and Patricia M. Flynn |
802 |
|
Chapter 58 |
Healthcare-Associated
Infections in Solid Organ Transplant Recipients Ryosuke
Osawa and
Nina Singh |
815 |
|
Chapter 59 |
Infection Prevention
and Control in Hematopoietic
Stem Cell Transplant Patients Leilani Paitoonpong, Dionissios Neofytos, Sara E. Cosgrove, and Trish M. Perl |
836 |
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SECTION VIII |
EPIDEMIOLOGY AND PREVENTION OF HEALTHCARE-ASSOCIATED J
INFECTIONS RELATED TO DIAGNOSTIC AND THERAPEUTIC PROCEDURES |
|
|
Chapter 60 |
Healthcare-Associated
Infections in Anesthesia Loreen A. Herwaldt, Matthew D.
Koff, Randy W. Loftus, and Jean M. Pottinger |
873 |
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Chapter 61 |
Healthcare-Associated
Infections that Complicate Invasive Procedures in Cardiology Winfried Ebner and Markus Dettenkofer |
913 |
|
Chapter 62 |
Infection
Risks of Endoscopy John Holton |
922 |
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Chapter 63 |
Control of Infections
Associated with Hemodialysis Pritl R. Patel, Nicola D. Thompson,
and Matthew J. Arduino |
936 |
|
Chapter 64 |
Infections
Associated with Peritoneal Dialysis John
J. Szela and Jeffrey D. Band |
957 |
|
Chapter 65 |
Infections
that Complicate the Insertion of Prosthetic Devices Ilker
Uçkay,
Daniel P. Lew, and Didier Pittet |
967 |
|
Chapter 66 |
Healthcare-Associated
Infections Related to Respiratory Therapy Keith
S. Kaye, Dror Marchaim, David J. Weber, and William A. Rutala |
978 |
|
Chapter 67 |
Healthcare-Associated
Infections Following Transfusion of Blood and Blood Products Charles J. Schleupner and Eyad Cheikh |
990 |
|
Chapter 68 |
Healthcare-Associated
Infections Related to Procedures Performed in Radiology Bruce S. Ribner |
1018 |
|
Chapter 69 |
Infection
Control in Gene Therapy Martin
E. Evans, David J. Weber, and William A. Rutala |
1026 |
|
SECTION IX |
PREVENTION OF HEALTHCARE-ASSOCIATED INFECTIONS RELATED
TO THE HOSPITAL ENVIRONMENT |
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|
Chapter 70 |
Central
Sterile Supply Lynne M. Sehulster |
1035 |
|
Chapter 71 |
Healthcare-Associated
Infections and the Environment Andrew
J. 5treifel |
1051 |
|
Chapter 72 |
Microbiologic
Sampling of the Environment in Healthcare Facilities Lynne M. 5ehulster, Laura J. Rose, and Judith Noble-Wang |
1059 |
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SECTION X |
EPIDEMIOLOGY AND PREVENTION OF HEALTHCARE-ASSOCIATED
INFECTIONS IN HEALTHCARE WORKERS |
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Chapter 73 |
Prevention
of Occupationally Acquired Viral Hepatitis in Healthcare Workers David K. Henderson and Susan E. Beekmann |
1076 |
|
Chapter 74 |
Prevention
of Occupationally Acquired Human Immunodeficiency Virus Infection in
Healthcare Workers Susan
E. Beekmann and David K. Henderson |
1096 |
|
Chapter 75 |
Vaccination
of Healthcare Workers Michael
D. Decker, David J. Weber, and William A. Schaffner |
1112 |
|
Chapter 76 |
Prevention
of Occupationally Acquired Diseases of Healthcare Workers Spread by Contact,
Droplet, or Airborne Routes (Other Than Tuberculosis) Titus L. Daniels,
Michael D. Decker, and William
A. Schaffner |
1128 |
|
Chapter 77 |
Prevention
of Occupationally-Acquired Healthcare-Associated Infections in Diagnostic
Laboratories Thomas J. Kirn, Susan E. Boruchoff, and
Melvin P. Weinstein |
1148 |
|
Chapter 78 |
Prevention
of Occupationally Acquired Infections in Prehospital Healthcare Workers James M. Melius |
1158 |
|
Chapter 79 |
Prevention
of Occupationally-Acquired Infections in Posthospital Healthcare Workers Charles W. Stratton IV |
1163 |
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SECTION XI |
DISINFECTION AND STERILIZATION |
|
|
Chapter 80 |
Selection
and Use of Disinfectants in Healthcare William
A. Rutala and David J. Weber |
1180 |
|
Chapter 81 |
Sterilization
and Pasteurization in Healthcare Facilities Lynne M. Sehulster and
Walter W. Bond |
1213 |
|
SECTION XII |
PREVENTION OF INFECTIONS ACQUIRED BY PATIENTS IN
HEALTHCARE FACILITIES RELATED TO DESIGN, CONSTRUCTION, RENOVATION,
DEMOLITION, AND VENTILATION SYSTEMS |
|
|
Chapter 82 |
Elements of
Design Aimed at Infection Prevention and Patient Safety in The Built
Environment of the Healthcare Facility Judene M. Bartley and Russell N. Olmsted |
1230 |
|
Chapter 83 |
Prevention
of Infections Related to Construction, Renovation, and Demolition in
Healthcare Facilities Iudene M. Bartley and Russell N. Olmsted |
1241 |
|
Chapter 84 |
Design and
Maintenance of Hospital Ventilation Systems and the Prevention of Airborne
Healthcare-Associated Infections Andrew
J.Stre1fel |
1268 |
|
SECTION XIII |
ANTIMICROBIAL AGENTS IN HEALTHCARE EPIDEMIOLOGY AND
INFECTION CONTROL |
|
|
Chapter 85 |
Mechanisms
of Bacterial Resistance to Antimicrobial Agents Usha
Stiefel
and Louis B. Rice |
1281 |
|
Chapter 86 |
Antimicrobial
Resistance and Healthcare-Associated Infections Gary L. French |
1297 |
|
Chapter 87 |
Antimicrobial
Stewardship Dilip Nathwani |
1311 |
|
SECTION XIV |
THE LITERATURE IN HEALTHCARE EPIDEMIOLOGY AND INFECTION
CONTROL |
|
|
Chapter 88 |
A Methodologically
Focused Review of the Literature in Healthcare Epidemiology and Infection
Control Matthew Samore and
Stephan I. Harbarth |
1319 |
|
SECTION XV |
ORGANIZATION AND IMPLEMENTATION OF INFECTION CONTROL
PROGRAMS |
|
|
Chapter 89 |
Surveillance
of Healthcare-Associated Infections Katherine
Allen-Bridson,
Gloria C. Morrell, and Teresa C. Horan |
1329 |
|
Chapter 90 |
Isolation
of Patients with Communicable Diseases Jason
E. Bowling, Jose Cadena, and Jan
Evans Patterson |
1344 |
|
Chapter 91 |
Hand
Washing and Hand Disinfection Manfred
L. Rotter |
1365 |
|
Chapter 92 |
Education
of Healthcare Workers in the Prevention of Healthcare-Associated Infections Karen K. Hoffmann and Eva P. Clontz |
1384 |
|
Chapter 93 |
Infection
Control and the Employee Health Service Pamela
S. Falk |
1393 |
|
Chapter 94 |
Epidemiology
and Prevention of Healthcare-Associated Infections Related to Animals in the
Hospital David J. Weber and William A. Rutala |
1401 |
|
Chapter 95 |
Role of the
Microbiology Laboratory and Molecular Epidemiology in Healthcare Epidemiology
and Infection Control Charles
W. Stratton Iv and John N. Greene |
1418 |
|
Chapter 96 |
Economic
Analysis in Healthcare Epidemiology Linda
M. Mundy and Anucha Apisarnthanarak |
1432 |
|
Chapter 97 |
Legal
Issues in Healthcare Epidemiology and Infection Control Mary Anne Bobinski |
1441 |
|
SECTION XVI |
HEALTHCARE EPIDEMIOLOGY AND INFECTION CONTROL IN SPECIAL
SETTINGS FOR HEALTHCARE DELIVERY |
|
|
Chapter 98 |
Epidemiology
and Prevention of Infections in Residents of Long-Term Care Facilities Jennie Johnstone and
Mark Loeb |
1451 |
|
Chapter 99 |
Epidemiology
and Prevention of Infections in Home Healthcare Philip W. Smith
and Angela L. Hewlett |
1462 |
|
Chapter 100 |
Infection
Control in Countries with Limited Resources Paul A. Tambyah, Nordiah A. Jal1l, and Jennifer Ho |
1470 |
|
SECTION XVII |
BIOTERRORISM |
|
|
Chapter 101 |
Biological
Terrorism: an Overview Margaret
A. Hamburg and C. J. Peters |
1487 |
|
Chapter 102 |
the State
and Local Response to Bioterrorism Ann
I. Winters, Joel Ackelsberg, Marcelle Layton,
Marc Paladini,
Debra Berg, and Sara T. Beatrice |
1494 |
|
Chapter 103 |
Agents of
Bioterrorism Michael Osterholm,
Elizabeth Linner
Mcclure,
and C. J. Peters |
1511 |
|
Chapter 104 |
Preparedness
for a Bioterrorist Attack with Smallpox Whitni B. Davidson, Andrea M. Mccollum, and Inger K. Damon |
1526 |
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Index |
1541 |
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