SECTION 1

NASAL CAVITY AND PARANASAL SINUSES

Congenital/Genetic/Hereditary

Nasal Glial Heterotopia   Lester D.R. Thompson, MD

1-2

Nasal Dermoid Cyst and Sinus   Bruce M. Wenig, MD

1-4

Primary Ciliary Dyskinesia   Bruce M. Wenig, MD

1-6

Infectious

Allergic Fungal Sinusitis   Lester D.R. Thompson, MD

1-8

Mycetoma   Lester D.R. Thompson, MD

1-12

Invasive Fungal Sinusitis   Bruce M. Wenig, MD

1-14

Rhinoscleroma   Lester D.R. Thompson, MD

1-16

Rhinosporidiosis   Bruce M. Wenig, MD

1-18

Mycobacteria Leprae Infection   Bruce M. Wenig, MD

1-20

Inflammatory-Immune Dysfunction

Chronic Rhinosinusitis   Bruce M. Wenig, MD

1-22

Wegener Granulomatosis   Bruce M. Wenig, MD

1-26

Eosinophilic Angiocentric Fibrosis   Bruce M. Wenig, MD

1-32

Reactive

Sinonasal Inflammatory Polyp   Bruce M. Wenig, MD

1-34

Antrochoanal Polyp   Bruce M. Wenig, MD

1-38

Sinonasal Hamartoma   Bruce M. Wenig, MD

1-40

Mucocele of Paranasal Sinus   Bruce M. Wenig, MD

1-44

Extranodal Sinus Histiocytosis with Massive Lymphadenopathy Bruce M. Wenig, MD   

1-46

Myospherulosis   Bruce M. Wenig, MD

1-50

Benign Neoplasm

Sinonasal (Schneiderian) Papilloma   Bruce M. Wenig, MD

1-52

Pleomorphic Adenoma   Lester D.R. Thompson, MD

1-58

Ectopic Pituitary Adenoma   Lester D.R. Thompson, MD

1-60

Meningioma   Lester D.R. Thompson, MD

1-66

Ameloblastoma   Lester D.R. Thompson, MD

1-68

Lobular Capillary Hemangioma (Pyogenic Granuloma)   Lester D.R. Thompson, MD

1-70

Schwannoma/Neurofibroma   Lester D.R. Thompson, MD

1-74

Leiomyoma & Smooth Muscle Tumors of Uncertain Malignant Potential    Bruce M. Wenig, MD

1-78

Fibromatosis/Desmoid-Type Fibromatosis   Lester D.R. Thompson, MD

1-82

Solitary Fibrous Tumor Lester D.R. Thompson, MD

1-84

Myxoma/Fibromyxoma   Bruce M. Wenig, MD

1-88

Borderline Neoplasm

Glomangiopericytoma (Sinonasal-type Hemangiopericytoma)   Lester D.R. Thompson, MD

1-90

Malignant Neoplasm

Squamous Cell Carcinoma   Bruce M. Wenig, MD

1-94

Sinonasal Undifferentiated Carcinoma   Bruce M. Wenig, MD

1-100

Lymphoepithelial Carcinoma   Bruce M. Wenig, MD

1-106

Sinonasal Adenocarcinoma, Intestinal Type   Bruce M. Wenig, MD

1-108

Sinonasal Nonintestinal-Nonsalivary   Adenocarcinoma Bruce M. Wenig, MD

1-114

Olfactory Neuroblastoma   Lester D.R. Thompson, MD

1-118

Malignant Mucosal Melanoma   Lester D.R. Thompson, MD

1-128

Ewing Sarcoma   Lester D.R. Thompson, MD

1-134

Teratocarcinosarcoma   Lester D.R. Thompson, MD

1-140

Fibrosarcoma   Lester D.R. Thompson, MD

1-144

Leiomyosarcoma   Bruce M. Wenig, MD

1-148

Malignant Peripheral Nerve Sheath Tumor   Bruce M. Wenig, MD

1-152

Malignant Fibrous Histiocytoma/ Undifferentiated Pleomorphic Sarcoma   Bruce M. Wenig, MD

1-156

Mesenchymal Chondrosarcoma   Francis H. Gannon, MD

1-160

Angiosarcoma   Lester D.R. Thompson, MD

1-162

Extranodal NK-/T-cell Lymphoma, Nasal Type   Bruce M. Wenig, MD

1-166

Metastatic/Secondary Tumors   Lester D.R. Thompson, MD

1-172

Specimen Examination, Nasal Cavity & Paranasal Sinuses

Protocol for the Examination of Nasal Cavity and Paranasal Sinus Specimens   Lester D.R. Thompson, MD

1-174

SECTION 2

PHARYNX (NASAL, ORO-, HYPO-)

Congenital/Genetic/Hereditary

Dermoid Cyst   Bruce M. Wenig, MD

2-2

Rathke Cleft Cyst   Lester D.R. Thompson, MD

2-4

Tornwaldt Cyst   Lester D.R. Thompson, MD

2-6

Tangier Disease Lester D.R. Thompson, MD

2-8

Infectious

Infectious Mononucleosis   Bruce M. Wenig, MD

2-10

HIV Infection of Tonsils and Adenoids   Bruce M. Wenig, MD

2-14

Reactive

Hairy Polyp   Bruce M. Wenig, MD

2-18

Benign Neoplasm

Nasopharyngeal Angiofibroma   Lester D.R. Thompson, MD

2-20

Malignant Neoplasm

Nasopharyngeal Carcinoma, Nonkeratinizing Types   Bruce M. Wenig, MD

2-24

Nasopharyngeal Carcinoma, Keratinizing Type   Bruce M. Wenig, MD

2-32

Nasopharyngeal Carcinoma, Basaloid Squamous Cell Carcinoma   Bruce M. Wenig, MD

2-34

Nasopharyngeal Papillary Adenocarcinoma   Bruce M. Wenig, MD

2-38

Diffuse Large B-cell Lymphoma   Bruce M. Wenig, MD

2-40

Staging and Grading, Pharynx

Protocol for the Examination of Pharynx Specimens   Lester D.R. Thompson, MD

2-44

SECTION 3

LARYNX AND TRACHEA

Congenital/Genetic/Hereditary

Laryngocele and Laryngeal Cysts   Nina Gale, MD, PhD and Lester D.R. Thompson, MD

3-2

Tracheopathia Osteoplastica   Lester D.R. Thompson, MD

3-4

Infectious

Laryngitis: Viral, Bacterial, Fungal   Lester D.R. Thompson, MD

3-6

Reactive

Vocal Cord Nodules and Polyps   Lester D.R. Thompson, MD

3-10

Reactive Epithelial Changes   Nina Gale, MD, PhD and Lester D.R. Thompson, MD

3-14

Contact Ulcer   Lester D.R. Thompson, MD

3-18

Benign Neoplasm

Squamous Papilloma   Nina Gale, MD, PhD and Lester D.R. Thompson, MD

3-20

Granular Cell Tumor   Nina Gale, MD, PhD and Lester D.R. Thompson, MD

3-24

Amyloid (Amyloidoma)   Lester D.R. Thompson, MD

3-26

Adult Rhabdomyoma   Nina Gale, MD, PhD and Lester D.R. Thompson, MD

3-28

Chondroma   Lester D.R. Thompson, MD

3-30

Inflammatory Myofibroblastic Tumor   Bruce M. Wenig, MD

3-32

Paraganglioma   Nina Gale, MD, PhD and Lester D.R. Thompson, MD

3-36

Malignant Neoplasm

Keratinizing Dysplasia and Carcinoma in Situ   Bruce M. Wenig, MD

3-38

Conventional Squamous Cell Carcinoma   Lester D.R. Thompson, MD

3-46

Vertucous Squamous Cell Carcinoma   Lester D.R. Thompson, MD

3-54

Spindle Cell “Sarcomatoid” Squamous Cell Carcinoma   Lester D.R. Thompson, MD

3-58

Basaloid Squamous Cell Carcinoma   Lester D.R. Thompson, MD

3-64

Exophytic and Papillary Squamous Cell   Carcinoma Lester D.R. Thompson, MD

3-66

Adenosquamous Carcinoma   Lester D.R. Thompson, MD

3-70

Neuroendocrine Carcinoma   Bruce M. Wenig, MD

3-74

Chondrosarcoma   Lester D.R. Thompson, MD

3-82

Metastatic/Secondary Tumors   Lester D.R. Thompson, MD

3-86

Specimen Examination, Larynx

Protocol for the Examination of Larynx Specimens   Lester D.R. Thompson, MD

3-88

SECTION 4

ORAL CAVITY

Congenital/Genetic/Hereditary

Ectopic (Lingual) Thyroid   Susan Müller, DMD, MS

4-2

White Sponge Nevus   Susan Müller, DMD, MS

4-4

Infectious

Hairy Leukoplakia   Susan Müller, DMD, MS

4-6

Oral Infections   Susan Müller, DMD, MS

4-8

Focal Epithelial Hyperplasia (Heck Disease)   Susan Muller, DMD, MS

4-14

Inflammatory-Immune Dysfunction

Aphthous Stomatitis   Susan Müller, DMD, MS

4-16

Pemphigus Vulgaris   Susan Müller, DMD, MS

4-20

Mucous Membrane Pemphigoid (Cicatricial Pemphigoid)   Susan Müller, DMD, MS

4-22

Lichen Planus   Susan Müller, DMD, MS

4-24

Erythema Multiforme   Susan Müller, DMD, MS

4-28

Lupus Erythematosus   Susan Müller, DMD, MS

4-30

Reactive

Traumatic Ulcer   Susan Müller, DMD, MS

4-34

Frictional Hyperkeratosis   Susan Müller, DMD, MS

4-36

Pseudoepitheliomatous Hyperplasia   Susan Müller, DMD, MS

4-37

Necrotizing Sialometaplasia   Kevin R. Torske, DDS, MS

4-38

Lymphangiomatous Polyp   Lester D.R. Thompson, MD

4-40

Amalgam Tattoo   Susan Müller, DMD, MS

4-42

Nonneoplastic Lesions

Fordyce Granules   Susan Müller, DMD, MS

4-43

Geographic Tongue   Brenda L. Nelson, DDS, MS

4-44

Juxtaoral Organ of Chievitz   Susan Müller, DMD, MS

4-46

Heterotopic Salivary Glands   Kevin R. Torske, DDS, MS

4-47

Mucocele and Ranula   Susan Müller, DMD, MS

4-48

Benign Neoplasm

Squamous Papilloma (Including Verruca and Condyloma)   Susan Müller, DMD, MS

4-50

Granular Cell Tumor   Lester D.R. Thompson, MD

4-54

Congenital Epulis of the Newborn   Susan Müller, DMD, MS

4-58

Pyogenic Granuloma   Susan Müller, DMD, MS

4-60

Peripheral Giant Cell Granuloma   Brenda L. Nelson, DDS, MS

4-62

Fibroma   Brenda L. Nelson, DDS, MS

4-64

Peripheral Ossifying Fibroma   Brenda L. Nelson, DDS, MS

4-66

Mucosal Neuroma   Brenda L. Nelson, DDS, MS

4-68

Acquired Melanocytic Nevus   Susan Müller, DUD, MS

4-70

Teratoma   Brenda L. Nelson, DDS, MS

4-74

Ectomesenchymal Chondromyxoid Tumor   Brenda L. Nelson, DDS, MS and Bruce M. Wenig, MD

4-76

Malignant Neoplasm

Dysplasia and Carcinoma in Situ   Susan Mailer, DMD, MS

4-80

Squampus Cell Carcinoma   Susan Müller, DMD, MS

4-86

Orcjpharyngeal Carcinoma   Susan Müller, DMD, MS

4-92

Melanoma   Susan Müller, DMD, MS & Lester D.R. Thompson, MD

4-96

Angiosarcoma   Brenda L. Nelson, DDS, MS

4-100

Kaposi Sarcoma   Susan Müller, DMD, MS

4-102

Metastatic/Secondary Tumors   Susan Müller, DMD, MS

4-104

Staging and Grading, Lip and Oral Cavity

Protocol for the Examination of Lip and Oral Cavity Specimens    Lester D.R. Thompson, MD

4-106

SECTION 5

SALIVARV GLANDS

Congenital/Genetic/Hereditary

Polycystic Disease of the Parotid   Kevin R. Torske, DDS, MS

5-2

Infectious

HIV Salivary Gland Disease   Bruce M. Wenig, MD

5-4

Inflammatory-Immune Dysfunction

Chronic Sclerosing Sialadenitis   Bruce M. Wenig, MD

5-8

Benign Lymphoepithelial Cyst   Kevin R. Torske, DDS, MS

5-12

Benign Lymphoepithelial Lesion   Kevin R, Torske, DDS, MS and Lester D.R. Thompson, MD

5-14

Sjogren Syndrome   Kevin R. Torske, DDS, MS and Lester D.R. Thompson, MD

5-16

Reactive

Oncocytosis (Oncocytic Hyperplasia)   Kevin R. Torske, DDS, MS

5-22

Sclerosing Polycystic Adenosis   Kevin R. Torske, DDS, MS

5-24

Sialolithiasis   Kevin R. Torske, DDS, MS

5-26

Benign Neoplasm

Pleomorphic Adenoma   Brenda L. Nelson, DDS, MS

5-28

Myoepithelioma   Kevin R. Torske, DDS, MS

5-36

Basal Cell Adenoma   Kevin R. Torske, DDS, MS

5-38

Warthin Tumor (Papillary Cystadenoma Lymphomatosum)   Bruce M. Wenig, MD

5-40

Oncocytoma   Lester D.R. Thompson, MD

5-44

Canalicular Adenoma   LesterD.R. Thompson, MD

5-50

Lymphadenoma and Sebaceous Lymphadenoma   Kevin R. Torske, DDS, MS

5-52

Sebaceous Adenoma   Kevin R. Torske, DDS, MS

5-54

Ductal Papillomas   Bruce M. Wenig, MD

5-56

Cystadenoma   Kevin R. Torske, DDS, MS

5-60

Hemangioma   Lester D.R. Thompson, MD

5-62

Malignant Neoplasm

Mucoepidermoid Carcinoma   Brenda L. Nelson, DDS, MS

5-66

Adenoid Cystic Carcinoma   Brenda L. Nelson, DDS, MS and Lester D.R. Thompson, MD

5-74

Acinic Cell Carcinoma   Lester D.R. Thompson, MD

5-82

Polymorphous Low-Grade Adenocarcinoma   Lester D.R. Thompson, MD

5-90

Carcinoma Ex-Pleomorphic Adenoma   Lester D.R. Thompson, MD

5-96

Salivary Duct Carcinoma   Lester D.R. Thompson, MD

5-104

Epithelial-Myoepithelial Carcinoma   Lester D.R. Thompson, MD

5-112

Adenocarcinoma, Not Otherwise Specified   Brenda L. Nelson, DDS, MS

5-118

Clear Cell Carcinoma (Hyalinizing/Sclerosing)   Kevin R. Torske, DDS, MS

5-120

Cystadenocarcinoma (Papillary)   Lester D.R. Thompson, MD

5-122

Myoepithelial Carcinoma   Brenda L. Nelson, DDS, MS

5-126

Small Cell Undifferentiated Carcinoma   Lester D.R. Thompson, MD

5-130

Lymphoepithelial Carcinoma   Bruce M. Wenig, MD

5-134

Basal Cell Adenocarcinoma   Lester D.R. Thompson, MD

5-138

Oncocytic Carcinoma   Bruce M. Wenig, MD

5-144

Sebaceous Carcinoma and Sebaceous Lymphadenocarcinoma   Lester D.R. Thompson, MD

5-148

Sialoblastoma   Lester D. K. Thompson, MD

5-152

Staging and Grading, Salivary Glands

Protocol for the Examination of Salivary Gland Specimens   Lester D.R. Thompson, MD

5-156

SECTION 6

JAW

Congenital/Genetic/Hereditary

Cherubism   Francis H. Gannon, MD and Lester D.R. Thompson, MD

6-2

Infectious

Osteomyelitis   Francis H. Gannon, MD and Lester D.R. Thompson, MD

6-6

Reactive

Tori   Susan Müller, DMD, MS

6-10

Fibrous Dysplasia   Francis H. Gannon, MD and Lester D.R. Thompson, MD

6-12

Osteoradionecrosis   Francis H. Gannon, MD and Lester D.R. Thompson, MD

6-16

Paget Disease of Bone   Francis H. Gannon, MD

6-20

Cysts

Central Giant Cell Lesion   Brenda L. Nelson, DDS, MS

6-24

Simple Bone Cyst   Brenda L. Nelson, DDS, MS

6-26

Dentigerous Cyst   Brmda L. Nelson, DDS, MS

6-28

Periapical Cyst/Granuloma   Brenda L. Nelson, DDS, MS

6-30

Benign Neoplasm

Ameloblastoma   Brenda L. Nelson, DDS, MS

6-32

Squamous Odontogenic Tumor   Brenda L. Nelson, DDS, MS

6-38

Calcifying Epithelial Odontogenic Tumor   Brenda L. Nelson, DDS, MS

6-40

Adenomatoid Odontogenic Tumor   Brenda L. Nelson, DDS, MS

6-42

Keratocystic Odontogenic Tumor (Odontogenic Keratocyst)   Brenda L. Nelson, DDS, MS

6-44

Ameloblastic Fibroma/Fibro-odontoma   Brenda L. Nelson, DDS, MS

6-48

Odontoma (Complex and Compound)   Brenda L. Nelson, DDS, MS

6-50

Central Odontogenic Fibroma   Brenda L. Nelson, DDS, MS

6-52

Calcifying Cystic Odontogenic Tumor   Brenda L. Nelson, DDS, MS

6-54

Cementoblastoma   Brenda L. Nelson, DDS, MS

6-56

Ossifying Fibroma   Francis H. Gannon, MD

6-58

Juvenile Active Ossifying Fibroma   Francis H. Gannon, MD and Lester D.R. Thompson, MD

6-60

Osteoma   Francis H. Gannon, MD

6-62

Osteoblastoma   Francis H. Gannon, MD

6-64

Melanotic Neuroectodermal Tumor of Infancy   Lester D.R. Thompson, MD

6-66

Malignant Neoplasm

Ameloblastic Carcinoma   Brenda L. Nelson, DDS, MS

6-68

Clear Cell Odontogenic Carcinoma   Brenda L. Nelson, DDS, MS

6-70

Ameloblastic Fibrosarcoma   Brenda L. Nelson, DDS, MS

6-72

Osteosarcoma   Francis H. Gannon, MD and Lester D.R. Thompson, MD

6-74

Chondrosarcoma   Francis H. Gannon, MD and Lester D.R. Thompson, MD

6-80

Fibrosarcoma   Francis H. Gannon, MD and Lester D.R. Thompson, MD

6-86

Plasma Cell Myeloma   Susan Müller, DMD, MS

6-88

SECTION 7

EAR AND TEMPORAL BONE

Congenital/Genetic/Hereditary

Accessory Tragus   Bruce M. Wenlg, MD

7-2

Encephalocele   Lester D.R. Thompson, MD

7-4

First Branchial Cleft Anomaly   Lester D.R. Thompson, MD

7-6

Infectious

Otitis Media   Francis H. Gannon, MD and Lester D.R. Thompson, MD

7-10

Necrotizing Otitis Externa   Bruce M. Wenig, MD

7-12

Inflammatory-Immune Dysfunction

Chondrodermatitis Nodularis Helicis   Lester D.R. Thompson, MD

7-14

Otic Polyp   Lester D.R. Thompson, MD

7-16

Relapsing Polychondritis   Lester D.R. Thompson, MD

7-18

Degenerative

Cystic Chondromalacia (Auricular Pseudocyst)   Lester D.R. Thompson, MD

7-20

Otosclerosis   Francis H. Gannon, MD

7-22

Metabolic

Gout   Francis H. Gannon, MD and Lester D.R. Thompson, MD

7-24

Reactive

Cholesteatoma   Lester D.R. Thompson, MD

7-26

Exostosis   Francis H. Gannon, MD

7-30

Keloid   David S. Cassarino, MD, PhD

7-32

Langerhans Cell Histiocytosis   Bruce M. Wenig, MD

7-34

Angiolymphoid Hyperplasia with Eosinophilia   Lester D.R. Thompson, MD

7-36

Malakoplakia   Lester D.R. Thompson, MD

7-38

Synovial Chondromatosis (Temporomandibular Joint)   Francis H. Gannon, MD and Lester D.R. Thompson, MD

7-40

Benign Neoplasm

Ceruminous Adenoma   Lester D.R. Thompson, MD

7-42

Middle Ear Adenoma   Lester D.R. Thompson, MD

7-46

Paraganglioma (Glomusjugulare/Tympanicum)   Lester D.R. Thompson, MD

7-52

Schwannoma (Acoustic Neuroma)   Lester D.R. Thompson, MD

7-58

Meningioma   Lester D.R. Thompson, MD

7-62

Endolymphatic Sac Tumor   Lester D.R. Thompson, MD

7-64

Malignant Neoplasm

Atypical Fibroxanthoma   David S. Cassarino, MD, PhD

7-68

Squamous Cell Carcinoma   David S. Cassarino, MD, PhD

7-72

Basal Cell Carcinoma   David S. Cassarino, MD, PhD

7-78

Merkel Cell Carcinoma   David S. Cassarino, MD, PhD

7-82

Dermatofibrosarcoma Protuberans   David S. Cassarino, MD, PhD

7-86

Ceruminous Adenocarcinoma   Lester D.R. Thompson, MD

7-90

Rhabdomyosarcoma   Lester D.R. Thompson, MD

7-94

Metastatic/Secondary Tumors   Lester D.R. Thompson, MD

7-100

SECTION 8

NECK (SOFT TISSUE AND LYMPH NODES)

Congenital/Genetic/Hereditary

Branchial Cleft Cyst   Lester D.R. Thompson, MD

8-2

Cervical Thymic Cyst   Brenda L. Nelson, DDS, MS and Bruce M. Wenig, MD

8-8

Bronchogenic Cyst   Brenda L. Nelson, DDS, MS

8-10

Infectious

Cat Scratch Disease   Lester D.R. Thompson, MD

8-12

Bacillary Angiomatosis   Bruce M. Wenig, MD

8-16

Mycobacterial Spindle Cell Pseudotumor   Bruce M. Wenig, MD

8-18

Inflammatory-Immune Dysfunction

Sarcoidosis   Bruce M. Wenig, MD

8-20

Reactive

Nodular Fasciitis   Lester D.R. Thompson, MD

8-22

Benign Neoplasm

Carotid Body Paraganglioma   Lester D.R. Thompson, MD

8-24

Elastofibroma   Lester D.R. Thompson, MD

8-30

Perineurioma   Lester D.R. Thompson, MD

8-32

Lipoma   Brenda L. Nelson, DDS, MS and Lester D.R. Thompson, MD

8-36

Spindle Cell Lipoma   Lester D.R. Thompson, MD

8-38

Lipoblastoma   Brenda L. Nelson, DDS, MS

8-40

Hibernoma   Lester D.R. Thompson, MD

8-42

Nuchal-type Fibroma   Brenda L. Nelson, DDS, MS and Lester D.R. Thompson, MD

8-44

Lymphangioma   Brenda L. Nelson, DDS, MS and Lester D.R. Thompson, MD

8-46

Malignant Neoplasm

Metastatic Cystic Squamous Cell Carcinoma   Lester D.R. Thompson, MD and Bruce M. Wenig, MD

8-48

Synovial Sarcoma   Lester D.R. Thompson, MD

8-56

Chordoma   Francis H. Gannon, MD and Lester D.R. Thompson, MD

8-62

Liposarcoma   Bruce M. Wenig, MD

8-68

SECTION 9

THYROID GLAND

Congenital/Genetic/Hereditary