PART I

GENERAL SECTION

1

History and Phylogeography of Leprosy   Stewart T. Cole and Pushpendra Singh

3

2

Microbiology   Andrea Clapasson and Silvia Canata

15

3

Genetics of Leprosy   Vinicius Medeiros Fava and Marcelo Tavora Mira

19

4

Host Response to M. leprae   Rodrigo Ribeiro-Rodrigues

27

5

Pathogenesis   Cesare Massone and Enrico Nunzi

39

6

Classification   Cesare Massone and Alexandra M. G. Brunasso

43

PART II

PATIENT’S EXAMINATION

7

Patient History   Enrico Nunzi, Cesare Massone and Salvatore Noto

51

8

Laboratory Investigations   Andrea Clapasson and Silvia Canata

55

PART III

SKIN

9

Physical Examination; Skin   Enrico Nunzi, Cesare Massone and Salvatore Noto

65

10

Clinical Features   Enrico Nunzi, Cesare Massone and Salvatore Noto

75

11

Lucio-Latapi Leprosy   Mario Magafia

111

12

Histopathology of the Skin   Cesare Massone

115

13

Differential Diagnosis: Skin   Enrico Nunzi and Salvatore Noto

137

PART IV

NERVES

14

Peripheral Nerves in Leprosy   Bernard Naafs and Jose Antfinio Garbino

153

15

The Leprosy Neuropathy   Lizia Reni, Salvatore Noto and Pieter A. M. Schreuder

163

16

Primary Neural Leprosy   Jose Antonio Garbino and Bernard Naafs

181

17

Chronic Neuropathic Pain in Leprosy   Jose Antonio Garbino, Bernard Naafs and Pedro Schestatsky

185

18

Electrodiagnostic Studies   Lizia Reni

191

19

Imaging   Carlo Martinoli, Leila Oppezzi and Alberto Tagliafico

197

20

Differential Diagnosis: Nerves   Lizia Reni

209

PART V

REACTIONS IN LEPROSY

21

Reactions in Leprosy   Bernard Naafs and Salvatore Noto

219

22

Lucio’s Phenomenon   Mario Magaiia

241

PART VI

SYSTEMIC INVOLVEMENT

23

Ocular Involvement in Leprosy   Susan Lewallen and Paul Courtright

247

24

Otolaryngological Manifestations of Leprosy   Sinesio Talhari, Camila Bandeira de Oliveira and Carolina Talhari

255

25

Other Organs   Enrico Nunzi and Salvatore Noto

261

PART VII

PATIENT’S MANAGEMENT

26

Diagnostic Work-Up   Enrico Nunzi, Cesare Massone and Salvatore Noto

271

27

Drugs in Leprosy   Sinesio Talhari and Mahreen Ameen

281

28

Treatment and Prophylaxis   Pierre Bobin

287

29

Prognosis   Enrico Nunzi

299

30

Neurolysis   Sergio S. G. Gennaro

303

31

Prevention of Disability and Ulcer Care   J. Wim Brandsma and Hugh Cross

309

32

Surgical and Social Rehabilitation   J. Wim Brandsma and Sunil Deepak

321

PART VIII

LEPROSY AND COMMUNITY

33

Leprosy in Pregnancy   Elizabeth Duncan

331

34

Leprosy and HIV/AIDS Co-infection   Sinesio Talhari and Carolina Talhari

341

35

Epidemiology of Leprosy   Salvatore Noto and Pieter A. M. Schreuder

347

36

Leprosy Control   Sunil Deepak and Giovanni Gazzoli

361

37

Teledermatology   Cesare Massone and Antonio Pedro Mendes Schettini

371

38

The Leprosy Mailing List   Salvatore Noto

375

Index

377