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Book Detail
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Computational and Experimental Design of Biopharmaceutical Formulations
Razinkov, Vladimir I.
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Publication Date: 04/2024 Status: Not Yet Published Audience: Professional and scholarly Retail Price: 150.00 (Tentative Price May Change)
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Synopsis:
Computational and Experimental Design of Biopharmaceutical Formulations outlines available experimental and computational tools. It describes a rational approach to formulation design not limited by experimental design that extends to modern methods of computational modeling. These methods include the modeling of protein structure and dynamics, and of solution properties in the presence of proteins and excipients. The chapters in this book consider computational modeling of protein-solution interactions, the design of early-stage formulation studies, the design of late-stage formulation studies, automation, high-throughput and control, design of lyophilized formulations, and emerging technologies in the future formulation development.
- Reviews methods for the design of biopharmaceutical formulations
- Considers both experimental and computational methods in concert
- Details design techniques specific to each step in protein formulation development
- Discusses the predictive power of methods used in formulation stability studies
- Describes and considers the potential of emerging models and experimental technologies
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