Book Detail
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Undergraduate Titles > Biochemistry
GPCRs as Therapeutic Targets, 2 Volume Set
Gilchrist, Annette
ISBN 13: 
9781119564744
ISBN 10: 
1119564743
Category: 
Biochemistry
Edition: 
1
Publisher: 
Wiley
Publication Date: 
06/2022
Format: 
Cloth
Status: 
Not Yet Published
Imprint: 
Wiley
Audience: 
Professional and scholarly
Pages: 
800
Weight: 
2
Retail Price: 
395.00 (Tentative Price May Change)
Quantity On Hand: 
0
Quantity On Order: 
0
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Synopsis:
The book provides a general overview of GPCRs in terms of their biology and pharmacology, how they react, and mutations relevant to disease development. In addition, it presents detailed methods on how to express, manipulate, and measure GPCRs. The new edition reviews current X-ray structures and offers insights into how the structures have expanded the understanding of allosteric and orthosteric binding sites, as well as GPCR activation through interactions with β-arrestin and heterotrimeric G proteins. This book on the shifting paradigms to GPCR pharmacology is an essential resource for drug discovery scientists working to identify compounds that selectively target members of this diverse family.

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