Book Detail
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Medicine > Nephrology
Polycystic Kidney Disease
Hu, Jinghua
ISBN 13: 
9781138603899
ISBN 10: 
1138603899
Category: 
Nephrology
Edition: 
1
Publisher: 
Taylor & Francis
Publication Date: 
11/2019
Format: 
Cloth
Status: 
Not Yet Published
Imprint: 
CRC Press
Pages: 
360
Weight: 
2
Retail Price: 
129.95 (Tentative Price May Change)
Quantity On Hand: 
0
Quantity On Order: 
0
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Synopsis:

This volume focuses on the investigatory methods applied to autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. ADPKD is caused by mutations in PKD1 and TRPP2, two integral membrane proteins that function as receptor/ion channel in primary cilia of tubular epithelial cells. Thus, ADPKD belongs to ciliopathies, a group of disordered caused by abnormal cilia formation or function. This proposed book will cover the state-of-the-art methods ranging from molecular biology, biochemistry, electrophysiology, to tools in model animal studies.

 

Key selling features:

  • Explores the role of cilia in polycystic kidney disease
  • Focuses on myriad state-of-the-art methods and techniques
  • Reviews specific mutations integral to this autosomal genetic disease
  • Includes discussions of model systems

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