The recent development of hypofractionated stereotactic radiation therapy (SRT), which calls for one to five fractions of high-dose radiation to be delivered using special equipment, has resulted in the need for education on practice guidelines. This comprehensive book provides how-to guidance on hypofractionated SRT for brain and spine metastases, glioma, benign tumors, and other tumor types. It outlines the current standards for safe practice as well as includes checklists for implementation. It also discusses the pros and cons of hypofractionated SRT compared to single-fraction radiosurgery.